232 research outputs found
Research qPCR Method for Engraftment Monitoring: A 6-Year Review of Proficiency Testing Results
Acceleration of Plasma Flows Due to Reverse Dynamo Mechanism
The "reverse-dynamo" mechanism - the amplification/generation of fast plasma
flows by micro scale (turbulent) magnetic fields via magneto-fluid coupling is
recognized and explored. It is shown that macro-scale magnetic fields and flows
are generated simultaneously and proportionately from micro scale fields and
flows. The stronger the micro-scale driver, the stronger are the macro-scale
products. Stellar and astrophysical applications are suggested.Comment: 16 pages including 3 figures. The Astrophys. J. (accepted);
additional material is given for clarification; terminology is change
Optical and Radio Variability of BL Lacertae
We observed the prototype blazar, BL Lacertae, extensively in optical and
radio bands during an active phase in the period 2010--2013 when the source
showed several prominent outbursts. We searched for possible correlations and
time lags between the optical and radio band flux variations using
multifrequency data to learn about the mechanisms producing variability. During
an active phase of BL Lacertae, we searched for possible correlations and time
lags between multifrequency light curves of several optical and radio bands. We
tried to estimate any possible variability timescales and inter-band lags in
these bands. We performed optical observations in B, V, R and I bands from
seven telescopes in Bulgaria, Georgia, Greece and India and obtained radio data
at 36.8, 22.2, 14.5, 8 and 4.8 GHz frequencies from three telescopes in
Ukraine, Finland and USA. Significant cross-correlations between optical and
radio bands are found in our observations with a delay of cm-fluxes with
respect to optical ones of ~250 days. The optical and radio light curves do not
show any significant timescales of variability. BL Lacertae showed many optical
'mini-flares' on short time-scales. Variations on longer term timescales are
mildly chromatic with superposition of many strong optical outbursts. In radio
bands, the amplitude of variability is frequency dependent. Flux variations at
higher radio frequencies lead the lower frequencies by days or weeks.
The optical variations are consistent with being dominated by a geometric
scenario where a region of emitting plasma moves along a helical path in a
relativistic jet. The frequency dependence of the variability amplitude
supports an origin of the observed variations intrinsic to the source.Comment: 10 pages, 9 figures, Accepted for publication in A&
Psychiatric symptoms and their association with sleep disturbances in intensive care unit survivors
Background:
Sleep disturbances in critically ill patients are associated with poorer long-term clinical outcomes and quality of life. Studies are needed to better characterize associations and risk factors for persistent sleep disturbances after intensive care unit (ICU) discharge. Psychiatric disorders are frequently associated with sleep disturbances, but the role of psychiatric symptoms in sleep disturbances in ICU survivors has not been well-studied.
Objective:
To examine the association between psychiatric symptoms and sleep disturbances in ICU survivors.
Methods:
112 adult ICU survivors seen from July 2011 to August 2016 in the Critical Care Recovery Center, an ICU survivor clinic at the Eskenazi Hospital in Indianapolis, IN, USA, were assessed for sleep disturbances (insomnia, hypersomnia, difficulty with sleep onset, difficulty with sleep maintenance, and excessive daytime sleepiness) and psychiatric symptoms (trauma-related symptoms and moderate to severe depressive symptoms) 3 months after ICU discharge. A multivariate logistic regression model was performed to examine the association between psychiatric symptoms and sleep disturbances. Analyses were controlled for age, hypertension, history of depression, and respiratory failure.
Results:
ICU survivors with both trauma-related and depression symptoms (OR 16.66, 95% CI 2.89-96.00) and trauma-related symptoms alone (OR 4.59, 95% CI 1.11-18.88) had a higher likelihood of sleep disturbances. Depression symptoms alone were no longer significantly associated with sleep disturbances when analysis was controlled for trauma-related symptoms.
Conclusion:
Trauma-related symptoms and trauma-related plus moderate to severe depressive symptoms were associated with a higher likelihood of sleep disturbances. Future studies are needed to determine whether psychiatric symptoms are associated with objective changes on polysomnography and actigraphy and whether adequate treatment of psychiatric symptoms can improve sleep disturbances
Impacts of mixed farms on water quality of Pinhal river sub-basin, Santa Catarina, Brazil.
Brazil is one of the largest producers of food in the world. Agriculture and livestock production are concentrated in certain regions of the country. Livestock has been perceived as a constant threat to the quantity and quality of water resources. The objective of this study was to evaluate the impact of mixed farms on superficial water quality in Pinhal River sub-basin, which is located in Concordia, Santa Catarina State. Eight sampling sites representing different land-uses (LU1: dairy cattle; LU2: without animals; LU3: dairy + pigs + poultry + crops; LU4: pigs + poultry + crops; LU5: dairy + pigs + poultry + crops + human; LU6: dairy + pigs + crops; LU7 and LU8: dairy + pigs) were evaluated. These sampling sites were assessed longitudinally and sampled during the summer, spring, autumn, and winter of 2006 to 2009. LU1 presented the worst water quality with high concentrations of total suspended solids (TSS) and chemical oxygen demand. In this point, cows had access to the river. The highest concentration of nitrate (NO3-N) was found at the estuary of the river. There were higher concentrations of TSS, NO3-N and NO2-N in wet season. At this time, intensive fertilizer application to corn fields is common. Autumn and winter presented the worst water quality with respect to nitrogen concentration. Results showed a strong relationship between the sources of pollution (e.g., cows, pigs and poultries) and water quality. Managing the use of animal manure with optimum chemical fertilizer applications along with riparian fencing may provide important mitigation options for protecting water quality of Pinhal River
Hospital outcomes in non-surgical patients identified at risk for OSA
Background: In-hospital respiratory outcomes of non-surgical patients with undiagnosed obstructive sleep apnea (OSA), particularly those with significant comorbidities are not well defined. Undiagnosed and untreated OSA may be associated with increased cardiopulmonary morbidity.
Study objectives: Evaluate respiratory failure outcomes in patients identified as at-risk for OSA by the Berlin Questionnaire (BQ).
Methods: This was a retrospective study conducted using electronic health records at a large health system. The BQ was administered at admission to screen for OSA to medical-service patients under the age of 80 years old meeting the following health system criteria: (1) BMI greater than 30; (2) any of the following comorbid diagnoses: hypertension, heart failure, acute coronary syndrome, pulmonary hypertension, arrhythmia, cerebrovascular event/stroke, or diabetes. Patients with known OSA or undergoing surgery were excluded. Patients were classified as high-risk or low-risk for OSA based on the BQ score as follows: low-risk (0 or 1 category with a positive score on the BQ); high-risk (2 or more categories with a positive score on BQ). The primary outcome was respiratory failure during index hospital stay defined by any of the following: orders for conventional ventilation or intubation; at least two instances of oxygen saturation less than 88% by pulse oximetry; at least two instances of respiratory rate over 30 breaths per minute; and any orders placed for non-invasive mechanical ventilation without a previous diagnosis of sleep apnea. Propensity scores were used to control for patient characteristics.
Results: Records of 15,253 patients were assessed. There were no significant differences in the composite outcome of respiratory failure by risk of OSA (high risk: 11%, low risk: 10%, p = 0.55). When respiratory failure was defined as need for ventilation, more patients in the low-risk group experienced invasive mechanical ventilation (high-risk: 1.8% vs. low-risk: 2.3%, p = 0.041). Mortality was decreased in patients at high-risk for OSA (0.86%) vs. low risk for OSA (1.53%, p < 0.001).
Conclusions: Further prospective studies are needed to understand the contribution of undiagnosed OSA to in-hospital respiratory outcomes
Multiband optical variability of the blazar OJ 287 during its outbursts in 2015 -- 2016
We present recent optical photometric observations of the blazar OJ 287 taken
during September 2015 -- May 2016. Our intense observations of the blazar
started in November 2015 and continued until May 2016 and included detection of
the large optical outburst in December 2016 that was predicted using the binary
black hole model for OJ 287. For our observing campaign, we used a total of 9
ground based optical telescopes of which one is in Japan, one is in India,
three are in Bulgaria, one is in Serbia, one is in Georgia, and two are in the
USA. These observations were carried out in 102 nights with a total of ~ 1000
image frames in BVRI bands, though the majority were in the R band. We detected
a second comparably strong flare in March 2016. In addition, we investigated
multi-band flux variations, colour variations, and spectral changes in the
blazar on diverse timescales as they are useful in understanding the emission
mechanisms. We briefly discuss the possible physical mechanisms most likely
responsible for the observed flux, colour and spectral variability.Comment: 11 pages, 6 figures, 4 tables; Accepted for publication in MNRA
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