Coherent and Differential Downlink Space-Time Steering Aided Generalised Multicarrier DS-CDMA

This paper presents a generalised MultiCarrier Direct Sequence Code Division Multiple Access (MC DS-CDMA) system invoking smart antennas for improving the achievable performance in the downlink. In this contribution, the MC DSCDMA transmitter employs an Antenna Array (AA) and Steered Space-Time Spreading (SSTS). Furthermore, the proposed system employs both Time and Frequency (TF) domain spreading for extending the capacity of the system, which is combined with a user-grouping technique for reducing the effects of Multi-User Interference (MUI). Moreover, to eliminate the high complexity Multiple Input Multiple Output (MIMO) channel estimation required for coherent detection, we also propose a Differential SSTS (DSSTS) scheme. More explicitly, for coherent SSTS detection MVNr number of channel estimates have to be generated, where M is the number of transmit AAs, V is the number of subcarriers and Nr is the number of receive antennas. This is a challenging task, which renders the low-complexity DSSTS scheme attractive. Index Terms—MIMO, MC DS-CDMA, beamforming, spacetime spreading, differential space-time spreading

An empirical analysis of competing explanations of urban primacy: Evidence from Asia and the Americas

This paper tests the relationship between primacy and economic development for countries in Asia and the Americas. It tests explanations for primacy drawn from several social-science disciplines--demography, economics, geography, political science, and sociology. The study is one of the first to use panel-data estimators for the tests. Economic and domestic political variables are found to be important determinants of primacy. In particular, rent-seeking and dictatorial governments are associated with primacy, but the association exists independent of the level of economic development. The implication from dependency and world-system theories that current international economic interactions promote primacy is not supported. It also examines the hypothesis that primacy first increases and then decreases with GDP per capita. --

Urban primacy, gigantism, and international trade: Evidence from Asia and the Americas

Gustavsson [1999] finds that policies that promote international trade increase the size of a country’s largest city relative to the country’s total population, which is defined here as an increase in urban gigantism. In contrast, Ades and Glaeser [1995] report urban gigantism is reduced by freer political institutions and, with less confidence, more open trade. In light of Henderson’s (2000) findings that excessive urban concentration inhibits economic growth, these conflicting results for the relationship between openness and urban gigantism (concentration), which are of great interest for the new economic geography, call for additional study. This study uses two measures of urban concentration and finds that lower international-trade costs are associated with lower primacy, but not with lower gigantism. Unlike Gustavsson, however, we find no evidence that lower trade costs increase gigantism. --

Mass-Galaxy offsets in Abell 3827, 2218 and 1689: intrinsic properties or line-of-sight substructures?

We have made mass maps of three strong-lensing clusters, Abell 3827, Abell 2218 and Abell 1689, in order to test for mass-light offsets. The technique used is GRALE, which enables lens reconstruction with minimal assumptions, and specifically with no information about the cluster light being given. In the first two of these clusters, we find local mass peaks in the central regions that are displaced from the nearby galaxies by a few to several kpc. These offsets {\em could\/} be due to line of sight structure unrelated to the clusters, but that is very unlikely, given the typical levels of chance line-of-sight coincidences in $\Lambda CDM$ simulations --- for Abell 3827 and Abell 2218 the offsets appear to be intrinsic. In the case of Abell 1689, we see no significant offsets in the central region, but we do detect a possible line of sight structure: it appears only when sources at z\ga 3 are used for reconstructing the mass. We discuss possible origins of the mass-galaxy offsets in Abell 3827 and Abell 2218: these include pure gravitational effects like dynamical friction, but also non-standard mechanisms like self-interacting dark-matter.Comment: 14 pages, 9 figures; Accepted for publication in MNRA

Association of inferior vena cava filter placement for venous thromboembolic disease and a contraindication to anticoagulation with 30-day mortality

Importance: Despite the absence of data from randomized clinical trials, professional societies recommend inferior vena cava (IVC) filters for patients with venous thromboembolic disease (VTE) and a contraindication to anticoagulation therapy. Prior observational studies of IVC filters have suggested a mortality benefit associated with IVC filter insertion but have often failed to adjust for immortal time bias, which is the time before IVC filter insertion, during which death can only occur in the control group. Objective: To determine the association of IVC filter placement with 30-day mortality after adjustment for immortal time bias. Design, Setting, and Participants: This comparative effectiveness, retrospective cohort study used a population-based sample of hospitalized patients with VTE and a contraindication to anticoagulation using the State Inpatient Database and the State Emergency Department Database, part of the Healthcare Cost and Utilization Project of the Agency for Healthcare Research and Quality, from hospitals in California (January 1, 2005, to December 31, 2011), Florida (January 1, 2005, to December 31, 2013), and New York (January 1, 2005, to December 31, 2012). Data analysis was conducted from September 15, 2015, to March 14, 2018. Exposure: Inferior vena cava filter placement. Main Outcomes and Measures: Multivariable Cox proportional hazard models were constructed with IVC filters as a time-dependent variable that adjusts for immortal time bias. The Cox model was further adjusted using the propensity score as an adjustment variable. Results: Of 126 030 patients with VTE, 61 281 (48.6%) were male and the mean (SD) age was 66.9 (16.6) years. In this cohort, 45 771 (36.3%) were treated with an IVC filter, whereas 80 259 (63.7%) did not receive a filter. In the Cox model with IVC filter status analyzed as a time-dependent variable to account for immortal time bias, IVC filter placement was associated with a significantly increased hazard ratio of 30-day mortality (1.18; 95% CI, 1.13-1.22; P \u3c .001). When the propensity score was included in the Cox model, IVC filter placement remained associated with an increased hazard ratio of 30-day mortality (1.18; 95% CI, 1.13-1.22; P \u3c .001). Conclusions and Relevance: After adjustment for immortal time bias, IVC filter placement was associated with increased 30-day mortality in patients with VTE and a contraindication to anticoagulation. Randomized clinical trials are needed to determine the efficacy of IVC filter placement in patients with VTE and a contraindication to anticoagulation

Adding ROS Scavengers to Cold K\u3csup\u3e+\u3c/sup\u3e Cardioplegia Reduces Superoxide Emission During 2 h Global Cold Cardiac Ischemia

We reported that the combination of reactive oxygen species (ROS) quenchers Mn(III) tetrakis (4-benzoic acid) porphyrin (MnTBAP), catalase, and glutathione (MCG) given before 2 hours cold ischemia better protected cardiac mitochondria against cold ischemia and warm reperfusion (IR)-induced damage than MnTBAP alone. Here, we hypothesize that high K+ cardioplegia (CP) plus MCG would provide added protection of mitochondrial bioenergetics and cardiac function against IR injury. Using fluorescence spectrophotometry, we monitored redox balance, ie reduced nicotinamide adenine dinucleotide and flavin adenine dinucleotide (NADH/FAD), superoxide (O2 •−), and mitochondrial Ca2+ (m[Ca2+]) in the left ventricular free wall. Guinea pig isolated hearts were perfused with either Krebs Ringer’s (KR) solution, CP, or CP + MCG, before and during 27°C perfusion followed immediately by 2 hours of global ischemia at 27°C. Drugs were washed out with KR at the onset of 2 hours 37°C reperfusion. After 120 minutes warm reperfusion, myocardial infarction was lowest in the CP + MCG group and highest in the KR group. Developed left ventricular pressure recovery was similar in CP and CP + MCG and was better than in the KR group. O2 •−, m[Ca2+], and NADH/FAD were significantly different between the treatment and KR groups. O2 •− was lower in CP + MCG than in the CP group. This study suggests that CP and ROS quenchers act in parallel to improve mitochondrial function and to provide protection against IR injury at 27°C