2,953 research outputs found
Better Synchronizability Predicted by Crossed Double Cycle
In this brief report, we propose a network model named crossed double cycles,
which are completely symmetrical and can be considered as the extensions of
nearest-neighboring lattices. The synchronizability, measured by eigenratio
, can be sharply enhanced by adjusting the only parameter, crossed length
. The eigenratio is shown very sensitive to the average distance ,
and the smaller average distance will lead to better synchronizability.
Furthermore, we find that, in a wide interval, the eigenratio approximately
obeys a power-law form as .Comment: 4 pages, 5 figure
Class of exactly solvable SO(n) symmetric spin chains with matrix product ground states
We introduce a class of exactly solvable SO(n) symmetric Hamiltonians with
matrix product ground states. For an odd case, the ground state is a
translational invariant Haldane gap spin liquid state; while for an even case, the ground state is a spontaneously dimerized state with twofold
degeneracy. In the matrix product ground states for both cases, we identify a
hidden antiferromagnetic order, which is characterized by nonlocal string order
parameters. The ground-state phase diagram of a generalized SO(n) symmetric
bilinear-biquadratic model is discussed.Comment: 11 pages, 5 figure
Multi-phase SPH modelling of air effect on the dynamic flooding of a damaged cabin
The air flow may take effects on the responses of the damaged ship in the dynamic flooding process. It not only relates to the amount of inflow but also the stability of the ship. In order to accurately predict the responses of a damaged ship, it is essential to take the air into account. In this study, a multi-phase SPH model combined with a dummy boundary method is proposed. One of the advantages of the new SPH model in solving this nonlinear problem is that, it does not rely on other algorithms to track the interface of different phases but can easily deal with breaking, splashing and mixing. The stability and accuracy of the numerical model are verified by comparing with experimental and published numerical results. The air captured in the flooding process is further studied with focus on the exchange of air and water near the opening. Finally, the effects of the sizes and number of the deck openings on the air flow are analyzed. It is found that the air flow can reduce the kinematic energy of inflow water, leading to decreases in the dynamic moment formed by the flooding water and sinking rate of damaged cabin
Hybrid type-I InAs/GaAs and type-II GaSb/GaAs quantum dot structure with enhanced photoluminescence
We investigate the photoluminescence (PL) properties of a hybrid type-I InAs/GaAs and type-II GaSb/GaAs quantum dot (QD) structure grown in a GaAs matrix by molecular beam epitaxy. This hybrid QD structure exhibits more intense PL with a broader spectral range, compared with control samples that contain only InAs or GaSb QDs. This enhanced PL performance is attributed to additional electron and hole injection from the type-I InAs QDs into the adjacent type-II GaSb QDs. We confirm this mechanism using time-resolved and power-dependent PL. These hybrid QD structures show potential for high efficiency QD solar cell applications
Furanodiene alters mitochondrial function in doxorubicin-resistant MCF-7 human breast cancer cells in an AMPK-dependent manner
Furanodiene is a bioactive sesquiterpene isolated from the spice-producing Curcuma wenyujin plant (Y. H. Chen and C. Ling) (C. wenyujin), which is a commonly prescribed herb used in clinical cancer therapy by modern practitioners of traditional Chinese medicine. Previously, we have shown that furanodiene inhibits breast cancer cell growth both in vitro and in vivo, however, the mechanism for this effect is not yet known. In this study, therefore, we asked (1) whether cultured breast cancer cells made resistant to the chemotherapeutic agent doxorubicin (DOX) via serial selection protocols are susceptible to furanodiene\u27s anticancer effect, and (2) whether AMP-activated protein kinase (AMPK), which is a regulator of cellular energy homeostasis in eukaryotic cells, participates in this effect. We show here (1) that doxorubicin-resistant MCF-7 (MCF-7/DOXR) cells treated with furanodiene exhibit altered mitochondrial function and reduced levels of ATP, resulting in apoptotic cell death, and (2) that AMPK is central to this effect. In these cells, furanodiene (as opposed to doxorubicin) noticeably affects the phosphorylation of AMPK and AMPK pathway intermediates, ACLY and GSK-3β, suggesting that furanodiene reduces mitochondrial function and cellular ATP levels by way of AMPK activation. Finally, we find that the cell permeable agent and AMPK inhibitor compound C (CC), abolishes furanodiene-induced anticancer activity in these MCF-7/DOXR cells, with regard to cell growth inhibition and AMPK activation; in contrast, AICAR (5-aminoimidazole-4-carboxamide-1-β-4-ribofuranoside, acadesine), an AMPK activator, augments furanodiene-induced anticancer activity. Furthermore, specific knockdown of AMPK in MCF-7/DOXR cells protects these cells from furanodiene-induced cell death. Taken together, these findings suggest that AMPK and its pathway intermediates are promising therapeutic targets for treating chemoresistant breast cancer, and that furanodiene may be an important chemical agent incorporated in next-generation chemotherapy protocols
Twist-3 Distribute Amplitude of the Pion in QCD Sum Rules
We apply the background field method to calculate the moments of the pion
two-particles twist-3 distribution amplitude (DA) in QCD sum
rules. In this paper,we do not use the equation of motion for the quarks inside
the pion since they are not on shell and introduce a new parameter to
be determined. We get the parameter in this approach. If
assuming the expansion of in the series in Gegenbauer polynomials
, one can obtain its approximate expression which can be
determined by its first few moments.Comment: 12 pages, 3 figure
Smoothed particle hydrodynamics (SPH) model for coupled analysis of a damaged ship with internal sloshing in beam seas
The flooding of a damaged ship in waves is a complex process, often coupled with the internal and external liquid motion together with the ship hull motion. Paramount to the operation safety, in order to improve the prediction accuracy of ship motion during the flooding process, the strip theory is applied to study the dynamic response of the damaged ship in beam seas; a smoothed particle hydrodynamics (SPH) model is developed to consider the coupling effects of various factors including internal sloshing of intact cabins and damaged cabins and external waves. The numerical wave tank with a perfectly matched layer absorbing boundary condition is established and validated by the experimental results. The detailed sensitivity study is carried out focusing on the effects of damaged opening sizes, the relative position of opening, and the incident wave and the liquid loading conditions on the dynamic response of the damaged ship in regular beam waves. It is observed that the flooding process was slowed down and interrupted by the water exchanges at the damaged opening due to the dynamic motion. Compared with the opening facing the incident wave, the back one endangered the ship pronouncedly with large amplitude and frequency roll motion. It is also revealed that the liquid tank in the damaged ship imposes a significant influence on its rolling response. It is further demonstrated that the present SPH model is capable of handling the nonlinear phenomenon in a flooding process of a damaged ship
A new spectrometer using multiple gratings with a two-dimensional charge-coupled diode array detector
A new spectrometer with no moving parts uses a two-dimensional Si-based charge-coupled diode (CCD) array detector and an integrated grating consisting of three subgratings. The effective spectral range imaged on the detector is magnified threefold. The digitized spectral image in the 200–1000 nm wavelength range can be measured quickly. The nonlinear relationship between CCD pixel position and wavelength is corrected with multiple polynomial functions in the calibration procedure, which fits the data using a mathematical pattern-analysis method. The instrument can be applied for rapid spectroscopicdata analyses in many types of photoelectronic experiments and routine testing
Cardiac CT perfusion imaging of pericoronary adipose tissue (PCAT) highlights potential confounds in coronary CTA
Features of pericoronary adipose tissue (PCAT) assessed from coronary
computed tomography angiography (CCTA) are associated with inflammation and
cardiovascular risk. As PCAT is vascularly connected with coronary vasculature,
the presence of iodine is a potential confounding factor on PCAT HU and
textures that has not been adequately investigated. Use dynamic cardiac CT
perfusion (CCTP) to inform contrast determinants of PCAT assessment. From CCTP,
we analyzed HU dynamics of territory-specific PCAT, myocardium, and other
adipose depots in patients with coronary artery disease. HU, blood flow, and
radiomics were assessed over time. Changes from peak aorta time, Pa, chosen to
model the time of CCTA, were obtained. HU in PCAT increased more than in other
adipose depots. The estimated blood flow in PCAT was ~23% of that in the
contiguous myocardium. Comparing PCAT distal and proximal to a significant
stenosis, we found less enhancement and longer time-to-peak distally.
Two-second offsets [before, after] Pa resulted in [ 4-HU, 3-HU] differences in
PCAT. Due to changes in HU, the apparent PCAT volume reduced ~15% from the
first scan (P1) to Pa using a conventional fat window. Comparing radiomic
features over time, 78% of features changed >10% relative to P1. CCTP
elucidates blood flow in PCAT and enables analysis of PCAT features over time.
PCAT assessments (HU, apparent volume, and radiomics) are sensitive to
acquisition timing and the presence of obstructive stenosis, which may confound
the interpretation of PCAT in CCTA images. Data normalization may be in order.Comment: 13 pages, 8 figure
- …