Characterization of Hypertension Risk Factors at the Committee on Temporary Shelter

Introduction: The health of homeless populations is at risk due to a high prevalence of undiagnosed hypertension (HTN) and cardiovascular disease (CVD). The interaction of housing and socioeconomic status with the risk factors for HTN and CVD remains unclear. Prevention of HTN through a healthy diet, exercise, adequate sleep, and avoidance of tobacco has been well described, but financial limitations and competing priorities for shelter and food make blood pressure (BP) control difficult for this population. By characterizing the risk factors and awareness of hypertension within the homeless population at the Committee on Temporary Shelter Daystation (COTS) in Burlington, Vermont, we may be able to identify promising avenues for therapeutic intervention.https://scholarworks.uvm.edu/comphp_gallery/1226/thumbnail.jp

Interaction between barium oxide and barium containing chloride melt

Thermal analysis was applied to determine the liquidus temperatures in the NaCl-KCl-BaCl2-BaO system, with BaO concentration varied from 0 to 6 mole%. The temperature dependence of the BaO solubility in the NaCl-KCl-BaCl2 eutectic melt was investigated; the thermodynamic parameters of BaO dissolution were calculated. The caloric effects of melting of the NaCl-KCl- BaCl2 eutectic with barium oxide and barium oxychloride additions were studied. The type, morphology, and composition of oxychloride ionic groupings in the melt were determined in situ using Raman spectroscopy

SNP-АНАЛИЗ ГЕНЕТИЧЕСКОГО РАЗНООБРАЗИЯ ПШЕНИЦЫ БЕЛАРУСИ

We used a high-throughput array to evaluate the diversity of hexaploid wheat growing in Belarus under the breeding program through 384 gene-associated SNPs. The gene pool of winter and spring varieties are significantly different in frequency of 248 variants from 174 SNPs. The genetic structure of the Belarusian population of wheat has appeared similar to the Russian and Ukrainian varieties and is essentially different from west-European varieties. But it has a high variability and, consequently, a good genetic potential for the improvement through breeding.Проведено изучение генетического разнообразия пшеницы Беларуси на основе высокопропускного SNP маркирования. В целом из 384 использованных маркеров в исследуемой коллекции типирован 331 локус. Генофонды озимых и яровых сортов достоверно различаются по частотам 248 вариантов 174 SNP. Генетическая структура белорусских сортов обнаруживает значительное сходство с образцами российской и украинской селекции, но при этом обладает значительным запасом разнообразия, которое представляет хороший потенциал для создания новых высокопродуктивных адаптированных форм

Структурно-параметрическая оптимизация систем автоматического регулирования с дифференцированием промежуточного сигнала

The paper proposes to improve a standard automatic control double-circuit system while changing a differentiator by difference of complete and incomplete inertial area models of the regulated object and also by using a PID-regulator instead of a PI-regulator and a device for internal disturbance compensations. Methods for structural and parametric optimization of the main regulator and device for internal disturbance compensations that allow to improve the regulation process have been proposed in the paper.Предлагается совершенствовать типовую двухконтурную систему автоматического регулирования путем замены дифференциатора на разность полной и неполной моделей инерционного участка объекта регулирования, а также использования ПИД-регулятора вместо ПИ-регулятора и устройства компенсации внутреннего возмущения. Предложены методы структурно-параметрической оптимизации основного регулятора и устройства компенсации внутреннего возмущения, позволяющие повысить качество регулирования

ВЛИЯНИЕ ПОВЕРХНОСТНОЙ ОБРАБОТКИ ЗАГОТОВОК РАСПИЛОВОЧНЫХ ДИСКОВ НА АБРАЗИВНУЮ СПОСОБНОСТЬ И ИЗНОСОСТОЙКОСТЬ ФОРМИРУЕМОГО АЛМАЗОСОДЕРЖАЩЕГО ПОКРЫТИЯ

The paper proposes methods for preliminary machining of sawing disk lateral surfaces before their charging that  provide formation of micro-relief grains on them which are favorable for introduction. The experimental data reflect influence of accepted methods for machining initial disk blanks on abrasive ability and wear resistance of diamond-containing coatings which are obtained on them with the help of charging.Предложены способы предварительной обработки боковых поверхностей распиловочного диска перед операцией их шаржирования, обеспечивающие формирование на них благоприятного для внедрения зерен микрорельефа. Получены экспериментальные данные, отражающие влияние принятых способов обработки исходных заготовок дисков на абразивную способность и износостойкость получаемых на них методом шаржирования алмазосодержащих покрытий

Abscisic Acid Flux Alterations Result in Differential Abscisic Acid Signaling Responses and Impact Assimilation Efficiency in Barley under Terminal Drought Stress

Abscisic acid (ABA) is a central player in plant responses to drought stress. How variable levels of ABAabscisic acid under short-term versus long-term drought stress impact assimilation and growth in crops is unclear. We addressed this through comparative analysis, using two elite breeding lines of barley (Hordeum vulgare) that show senescence or stay-green phenotype under terminal drought stress and by making use of transgenic barley lines that express Arabidopsis (Arabidopsis thaliana) 9-cis-epoxycarotenoid dioxygenase (AtNCED6) coding sequence or an RNA interference (RNAi) sequence of ABA 8′-hydroxylase under the control of a drought-inducible barley promoter. The high levels of ABA and its catabolites in the senescing breeding line under long-term stress were detrimental for assimilate productivity, whereas these levels were not perturbed in the stay-green type that performed better. In transgenic barley, drought-inducible AtNCED expression afforded temporal control in ABA levels such that the ABA levels rose sooner than in wild-type plants but also subsided, unlike as in the wild type , to near-basal levels upon prolonged stress treatment due to down-regulation of endogenous HvNCED genes. Suppressing of ABA catabolism with the RNA interference approach of ABA 8′-hydroxylase caused ABA flux during the entire period of stress. These transgenic plants performed better than the wild type under stress to maintain a favorable instantaneous water use efficiency and better assimilation. Gene expression analysis, protein structural modeling, and protein-protein interaction analyses of the members of the PYRABACTIN RESISTANCE1/PYRABACTIN RESISTANCE1-LIKE/REGULATORY COMPONENT OF ABA RECEPTORS, TYPE 2C PROTEIN PHOSPHATASE Sucrose non-fermenting1-related protein kinase2, and ABA-INSENSITIVE5/ABA-responsive element binding factor family identified specific members that could potentially impact ABA metabolism and stress adaptation in barley

Spatial Structure of <i>Yersinia pestis</i> Population Belonging to Altai Biovar, Subspecies central asiatica Acording to Genome-Wide Sequencing Data

The aim of the work was to conduct phylogenetic analysis of Y. pestis strains, biovar altaica ssp. central asiatica, isolated in Gorno-Altai high-mountain and Sailyugem natural plague foci on the territory of Russia and Mongolia in 1965–2020, by full-genome sequencing data.Materials and methods. To determine the population structure of the biovar altaica ssp. central asiatica, 34 whole genome sequences were used (including 20 Y. pestis strains of the biovar altaica, 18 of which were sequenced by us). To isolate DNA from the Y. pestis strains, a PureLink Genomic DNA Mini Kit (Invitrogen, USA) was applied. Sequencing of the nucleotide sequences of Y. pestis strains was carried out in Ion PGM system Lifetechnologies. The analysis and processing of the obtained data were performed with the help of Newblergs Assembler 2.6 and IonTorrent Suite software package, 3.4.2. The search for SNPs was performed using the Wombac 2.0 program. The Maximum Likelihood dendrogram was built in the PhyML 3.1. The dendrogram was visualized using the FigTree 1.4.3 software.Results and discussion. Based on the data of whole genome analysis, taking into account the 1871 revealed polymorphic nucleotides, the spatial structure of the biovar altaica ssp. central asiatica has been determined. It includes several phylogeographic branches: the Kurai-Tarkhatinskaya (cluster 0.PE4a-1) and the Ulandryk-Mongolian (0.PE4a-2), which is in agreement with the geographical regions of the isolation of strains forming these branches in the Altai Mountains. The Kurai-Tarkhatinskaya branch is further divided into the Kurai (sub-cluster 0.PE4a-1-1, formed by the strains of 2009–2018) and Tarkhatinskaya (subcluster 0.PE4a-1-2, formed by the strains of 2012–2020) sub-branches, while the Ulandryk-Mongolian branch of evolution is split into sub-branches represented by strains from the Ulandryk meso focus (sub-cluster 0.PE4a-2-2, strains 1965–2010) and the Sailyugem focus of Mongolia (sub-cluster 0.PE4a-2-1, strains 1964–1990)