125 research outputs found
QGP fireball explosion
We identify the major physics milestones in the development of strange
hadrons as an observable for both the formation of quark-gluon plasma, and of
the ensuing explosive disintegration of deconfined matter fireball formed in
relativistic heavy ion collisions at 160--20A GeV. We describe the physical
properties of QGP phase and show agreement with the expectations based on an
analysis of hadron abundances. We than also demonstrate that the m_t shape of
hadron spectra is in qualitative agreement with the sudden breakup of a
supercooled QGP fireball.Comment: 10 pages, incl. 4 figures J. Phys. G in press; presented at
STRANGENESS2000 International Conference, Berkeley July 200
Extracting Classical Correlations from a Bipartite Quantum System
In this paper we discuss the problem of splitting the total correlations for
a bipartite quantum state described by the Von Neumann mutual information into
classical and quantum parts. We propose a measure of the classical correlations
as the difference between the Von Neumann mutual information and the relative
entropy of entanglement. We compare this measure with different measures
proposed in the literature.Comment: 5 pages, 1 figur
The efficacy of lenvatinib plus everolimus in patients with metastatic renal cell carcinoma exhibiting primary resistance to front-line targeted therapy or immunotherapy
BACKGROUND: Patients with primary refractory metastatic renal cell carcinoma (mRCC) have a dismal prognosis and poor response to subsequent treatments. While there are several approved second-line therapies, it remains critical to choose the most effective treatment regimen.
PATIENTS AND METHODS: We identified 7 patients with clear cell mRCC who had primary resistance to vascular endothelial growth factor (VEGF)-targeted tyrosine kinase inhibitors (TKIs) or immune checkpoint inhibitor (ICI) combination therapy. The patients were treated with lenvatinib (a multitargeted TKI) plus everolimus (a mammalian target of rapamycin inhibitor). Among these 7 patients, 2 had prior TKI therapy, 3 had prior ICI therapy, and 2 had prior TKI and ICI therapy. We collected the patients\u27 clinical characteristics, molecular profiles, treatment durations, and toxicity outcomes.
RESULTS: The median time to progression on prior therapies was 1.5 months. Lenvatinib plus everolimus was used either as a second-line (n = 4) or third-line (n = 3) therapy. As best responses, 3 patients had partial responses and 3 achieved stable disease. Patients were followed for ≥17 months; progression-free survival ranged from 3 to 15 months, and overall survival ranged from 4 to 17 months.
CONCLUSION: These 7 cases provide real-world data for the use of lenvatinib plus everolimus in patients with mRCC with primary resistance to first-line VEGF-targeted TKIs or ICI combination therapy
Lower bounds for heights in relative Galois extensions
The goal of this paper is to obtain lower bounds on the height of an algebraic number in a relative setting, extending previous work of Amoroso and Masser. Specifically, in our first theorem, we obtain an effective bound for the height of an algebraic number when the base field is a number field and is Galois. Our second result establishes an explicit height bound for any nonzero element which is not a root of unity in a Galois extension , depending on the degree of and the number of conjugates of which are multiplicatively independent over . As a consequence, we obtain a height bound for such that is independent of the multiplicative independence condition
Strangeness Content in the Nucleon
I review recent studies of strangeness content in the nucleon pertaining to
the flavor-singlet , the matrix element and the strangeness
electric and magnetic form factors and , based on
lattice QCD calculations. I shall also discuss the relevance of incorporating
the strangeness content in nuclei in regard to strange baryon-antibaryon
productions from proton-nucleus and nucleus-nucleus collisions at SPS and RHIC
energies.Comment: 11 pages, 4 figures, Invited talk at V Int. Conf. on Strangeness in
Quark Matter, Berkeley, CA, July 20--25, 200
Strange Particle Production at RHIC
We report STAR measurements of mid-rapidity yields for the ,
, , , , , and
particles in Cu+Cu and Au+Au GeV
collisions. We show that at a given number of participating nucleons, bulk
strangeness production is higher in Cu+Cu collisions compared to Au+Au
collisions at the same center of mass energy, counter to predictions from the
Canonical formalism. We compare both the Cu+Cu and Au+Au yields to AMPT and
EPOS predictions, and find they reproduce key qualitative aspects of the data.
Finally, we investigate other scaling parameters and find bulk strangeness
production for both the measured data and theoretical predictions, scales
better with the number participants that undergo more than one collision.Comment: Conference proceedings for Hot Quarks 2008, 5 pages and 4 figure
System Size Dependence of Particle Production at the SPS
Recent results on the system size dependence of net-baryon and hyperon
production as measured at the CERN SPS are discussed. The observed Npart
dependences of yields, but also of dynamical properties, such as average
transverse momenta, can be described in the context of the core corona
approach. Other observables, such as antiproton yields and net-protons at
forward rapidities, do not follow the predictions of this model. Possible
implications for a search for a critical point in the QCD phase diagram are
discussed. Event-by-event fluctuations of the relative core to corona source
contributions might influence fluctuation observables (e.g. multiplicity
fluctuations). The magnitude of this effect is investigated.Comment: 10 pages, 4 figurs. Proceedings of the 6th International Workshop on
Critical Point and Onset of Deconfinement in Dubna, Aug. 201
Entropy Production in Relativistic Hydrodynamics
The entropy production occurring in relativistic hydrodynamical systems such
as the quark-gluon plasma (QGP) formed in high-energy nuclear collisions is
explored. We study mechanisms which change the composition of the fluid, i.e.
particle production and/or chemical reactions, along with chemo- and
thermo-diffusion. These effects complement the conventional dissipative effects
of shear viscosity, bulk viscosity, and heat conductivity.Comment: 15 pages; LaTex. Accepted for publication in Physics Letters B. - Two
typos corrected and one reference adde
Resonances and fluctuations in the statistical model
We describe how the study of resonances and fluctuations can help constrain
the thermal and chemical freezeout properties of the fireball created in heavy
ion collisions. This review is based on [1-5].Comment: Proceedings,"Hadronic resonance production in heavy ion and
elementary collisions" UT Austin, March 5-7 201
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