17 research outputs found
MHC-IIB Filament Assembly and Cellular Localization Are Governed by the Rod Net Charge
Get PDFActin-dependent myosin II molecular motors form an integral part of the cell cytoskeleton. Myosin II molecules contain a long coiled-coil rod that mediates filament assembly required for myosin II to exert its full activity. The exact mechanisms orchestrating filament assembly are not fully understood., negatively-charged regions of the coiled-coil were found to play an important role by controlling the intracellular localization of native MHC-IIB. The entire positively-charged region is also important for intracellular localization of native MHC-IIB.A correct distribution of positive and negative charges along myosin II rod is a necessary component in proper filament assembly and intracellular localization of MHC-IIB
The histone chaperone DAXX maintains the structural organization of heterochromatin domains
Full text linkNon-Muscle Myosin II Regulates Neuronal Actin Dynamics by Interacting with Guanine Nucleotide Exchange Factors
No full textPAK1 and aPKCζ Regulate Myosin II-B Phosphorylation: A Novel Signaling Pathway Regulating Filament Assembly
No full textMyosin II regulates actin rearrangement-related structural synaptic plasticity during conditioned taste aversion memory extinction
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STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap
No full textModulation of Higher Order Chromatin Conformation in Mammalian Cell Nuclei Can Be Mediated by Polyamines and Divalent Cations
No full textEpigenetic Alterations at Genomic Loci Modified by Gene Targeting in Arabidopsis thaliana
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