20,020 research outputs found

    The Dynamics of Charges Induced by a Charged Particle Traversing a Dielectric Slab

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    We studied the dynamics of surfacea and wake charges induced by a charged particle traversing a dielectric slab. It is shown that after the crossing of the slab first boundary, the induced on the slab surface charge (image charge) is transformed into the wake charge, which overflows to the second boundary when the particle crosses it. It is also shown, that the polarization of the slab is of an oscillatory nature, and the net induced charge in a slab remains zero at all stages of the motion.Comment: 12 pages, 1 figur

    Can Foreign Policy Make a Difference to Health?

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    As part of the PLoS Medicine series on Global Health Diplomacy, Sigrun Møgedal and Benedikte Alveberg provide a diplomatic perspective on how foreign policy can make a difference to global health challenges

    Development of equations for converting random-zero to automated oscillometric blood pressure values

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    Abstract Objective This study aimed to collect data to compare blood pressure values between random-zero sphygmomanometers and automated oscillometric devices and generate equations to convert blood pressure values from one device to the other. Methods Omron HEM-907, a widely used automated oscillometric device in many epidemiologic surveys and cohort studies, was compared here with random-zero sphygmomanometers. Two hundred and one participants aged 40-79 years (37% men) were enrolled and randomly assigned to one of two groups with blood pressure measurement first taken by automated oscillometric devices or by random-zero sphygmomanometers. The study design enabled comparisons of blood pressure values between random-zero sphygmomanometers and two modes of this automated oscillometric device – automated and manual, and assessment of effects of measurement order on blood pressure values. Results Among all participants, mean blood pressure levels were lowest when measured with random-zero sphygmomanometers compared with both modes of automated oscillometric devices. Several variables, including age and gender, were found to contribute to the blood pressure differences between random-zero sphygmomanometers and automated oscillometric devices. Equations were developed using multiple linear regression after taking those variables into account to convert blood pressure values by random-zero sphygmomanometers to automated oscillometric devices. Conclusion Equations developed in this study could be used to compare blood pressure values between epidemiologic and clinical studies or identify shift of blood pressure distribution over time using different devices for blood pressure measurements

    Optofluidic microcavities : dye-lasers and biosensors

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    Author name used in this publication: Y. ChenAuthor name used in this publication: L. LeiAuthor name used in this publication: X. M. ZhangAuthor name used in this publication: Y. WangAuthor name used in this publication: H. L. W. Chan2010-2011 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

    Bioelectronic DNA detection of human papillomaviruses using eSensor™: a model system for detection of multiple pathogens

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    BACKGROUND: We used human papillomaviruses (HPV) as a model system to evaluate the utility of a nucleic acid, hybridization-based bioelectronic DNA detection platform (eSensor™) in identifying multiple pathogens. METHODS: Two chips were spotted with capture probes consisting of DNA oligonucleotide sequences specific for HPV types. Electrically conductive signal probes were synthesized to be complementary to a distinct region of the amplified HPV target DNA. A portion of the HPV L1 region that was amplified by using consensus primers served as target DNA. The amplified target was mixed with a cocktail of signal probes and added to a cartridge containing a DNA chip to allow for hybridization with complementary capture probes. RESULTS: Two bioelectric chips were designed and successfully detected 86% of the HPV types contained in clinical samples. CONCLUSIONS: This model system demonstrates the potential of the eSensor platform for rapid and integrated detection of multiple pathogens

    Approximating Weighted Duo-Preservation in Comparative Genomics

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    Motivated by comparative genomics, Chen et al. [9] introduced the Maximum Duo-preservation String Mapping (MDSM) problem in which we are given two strings s1s_1 and s2s_2 from the same alphabet and the goal is to find a mapping π\pi between them so as to maximize the number of duos preserved. A duo is any two consecutive characters in a string and it is preserved in the mapping if its two consecutive characters in s1s_1 are mapped to same two consecutive characters in s2s_2. The MDSM problem is known to be NP-hard and there are approximation algorithms for this problem [3, 5, 13], but all of them consider only the "unweighted" version of the problem in the sense that a duo from s1s_1 is preserved by mapping to any same duo in s2s_2 regardless of their positions in the respective strings. However, it is well-desired in comparative genomics to find mappings that consider preserving duos that are "closer" to each other under some distance measure [19]. In this paper, we introduce a generalized version of the problem, called the Maximum-Weight Duo-preservation String Mapping (MWDSM) problem that captures both duos-preservation and duos-distance measures in the sense that mapping a duo from s1s_1 to each preserved duo in s2s_2 has a weight, indicating the "closeness" of the two duos. The objective of the MWDSM problem is to find a mapping so as to maximize the total weight of preserved duos. In this paper, we give a polynomial-time 6-approximation algorithm for this problem.Comment: Appeared in proceedings of the 23rd International Computing and Combinatorics Conference (COCOON 2017

    Weak in Space, Log in Time Improvement of the Lady{\v{z}}enskaja-Prodi-Serrin Criteria

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    In this article we present a Lady{\v{z}}enskaja-Prodi-Serrin Criteria for regularity of solutions for the Navier-Stokes equation in three dimensions which incorporates weak LpL^p norms in the space variables and log improvement in the time variable.Comment: 14 pages, to appea
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