6 research outputs found
A Two-Input Fluorescent Logic Gate for Glutamate and Zinc
The direct visualization
of neurotransmitters is a continuing problem in neuroscience; however,
functional fluorescent sensors for organic analytes are still rare.
Herein, we describe a fluorescent sensor for glutamate and zinc ions.
The sensor acts as a fluorescent logic gate, giving a turn-off response
to glutamate or zinc ion alone. The combination of analytes produces
a large increase in fluorescence. This type of sensor will aid in
the study of neurotransmission, in this case, for neurons that copackage
high concentrations of zinc and glutamate