792 research outputs found

    Aspectos importantes para a obtenção de leite de cabra com qualidade.

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    Prevalence and Utilization of Medical Care Services in Persons with Autism Spectrum Disorder using Medicare Claims

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    Objective: To characterize the prevalence of autism spectrum disorder (ASD) among persons in Medicare claims and contrast with prevalence documented during disability determination in Social Security Administration (SSA) Supplemental Security Income (SSI) files. Poster presented at APHA in Chicago Illinois

    SIMBA: a web tool for managing bacterial genome assembly generated by Ion PGM sequencing technology

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    Background The evolution of Next-Generation Sequencing (NGS) has considerably reduced the cost per sequenced-base, allowing a significant rise of sequencing projects, mainly in prokaryotes. However, the range of available NGS platforms requires different strategies and software to correctly assemble genomes. Different strategies are necessary to properly complete an assembly project, in addition to the installation or modification of various software. This requires users to have significant expertise in these software and command line scripting experience on Unix platforms, besides possessing the basic expertise on methodologies and techniques for genome assembly. These difficulties often delay the complete genome assembly projects. Results In order to overcome this, we developed SIMBA (SImple Manager for Bacterial Assemblies), a freely available web tool that integrates several component tools for assembling and finishing bacterial genomes. SIMBA provides a friendly and intuitive user interface so bioinformaticians, even with low computational expertise, can work under a centralized administrative control system of assemblies managed by the assembly center head. SIMBA guides the users to execute assembly process through simple and interactive pages. SIMBA workflow was divided in three modules: (i) projects: allows a general vision of genome sequencing projects, in addition to data quality analysis and data format conversions; (ii) assemblies: allows de novo assemblies with the software Mira, Minia, Newbler and SPAdes, also assembly quality validations using QUAST software; and (iii) curation: presents methods to finishing assemblies through tools for scaffolding contigs and close gaps. We also presented a case study that validated the efficacy of SIMBA to manage bacterial assemblies projects sequenced using Ion Torrent PGM. Conclusion Besides to be a web tool for genome assembly, SIMBA is a complete genome assemblies project management system, which can be useful for managing of several projects in laboratories. SIMBA source code is available to download and install in local webservers at http://ufmg-simba.sourceforge.net

    Use of Medicare Claims as a Source for Research Prevalence and Utilization of Medical Care Services in Persons with Autism Spectrum Disorder Over and Under Age 65

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    Objective: 1. To evaluate the feasibility of using Medicare claims by determining the number of identifiable persons with autism spectrum disorder (ASD) in a three year limited data set (2008-2010) 2. To describe the structure, types, and limitations of Medicare claims files for ASD researc

    Purificação e caracterização parcial de uma toxina protéica presente na alga Vidalia obtusiloba (Mertens ex C. Agardh) J. Agardh.

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    Coleta e armazenagem de algas ; Preparação do extrato total e da fração 0/60 (F0/60); Determinação de proteínas; Atividade hemaglutinante; Atividade inibidora de tripsina; Atividade tóxica; Termoestabilidade das atividades hemaglutinantes e tóxicas; Cromatografia de troca iônica em coluna de DEAE-Sephacel; Cromatografia de interação hidrofóbica em coluna de Phenyl-Sepharose CL-4B; Cromatografia de exclusão molecular em coluna de superose -1 2 HR acoplada ao sistema de FPLC; Eletroforese em gel de poliacrilamida.bitstream/item/36601/1/Doc72.pd

    Supporting the Occupational Therapy Student in the Production and Dissemination of Systematic Reviews: An Interprofessional Collaboration among Librarians and Occupational Therapy Faculty

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    Objectives This poster describes the outcomes of a curriculum-based collaboration between librarians and OT faculty (‘collaboration’) to enhance graduate student skills for conducting a systematic review (SR); the collaboration included database instruction, bibliographic management software, and culminated in student presentations to healthcare practitioners for continuing education credit. Three outcome areas are discussed: impact of the collaboration on student satisfaction and perceived competence; characteristics of the included literature; and the dissemination of SR findings to healthcare practitioners. Methods Three librarians participated in the instruction and the institutional repository (Jefferson Digital Commons; JDC) deposits. A total of 132 students over a period of two years (2013-2014) completed the curriculum, engaging with librarians and OT faculty to iteratively build on skills. At the conclusion of their curriculum, the capstone presentations were recorded and made freely available through the JDC. Quantitative data were examined with descriptive statistics in SPSS, and qualitative data were thematically coded by hand: course evaluations, practitioner attendance, bibliographic evaluations of the systematic reviews, and download statistics from the institutional repository. Results Students reported on open-ended course evaluation questions that among the top three concepts learned was ‘how to conduct a replicable and effective search.’ On multiple answer questions 83.6% of students selected the ‘collaborative librarian-faculty lecture’ as among the most helpful lectures offered, and 78.2% selected ‘working with librarian staff and course mentors to develop a search strategy’ as highly rated among course activities. Bibliographic data were extracted from 22 of 28 capstone presentations available for analysis (2013-2014) in the institutional repository, which contained 305 citations from 157 journals. The average of age of included articles was 4.8 years (SD=4.2, Range=0-24). Among the top 10 cited journals were 2 occupational therapy, 5 rehabilitation, and 3 specialty. Overall health care practitioner attendance at student capstones from 2012-2014 was 323. JDC recordings (as of 1/6/2015) had been accessed from 25 different countries, and are located most frequently via Google, JDC, and GoogleScholar. The total number of views was 1,446, and the total number of hours viewed was 163 hours. Conclusions Librarian-faculty collaborations resulted in high student perception of competence to conduct systematic reviews, utilization of a broad variety of peer-reviewed journals, and enhanced dissemination of evidence
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