91 research outputs found

    Компьютерная система диагностирования трансмиссий мобильных машин

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    A new method for diagnostics of mechanical transmissions of mobile machinery is proposed in the paper. The method presupposes an application of computing equipment and its purpose is to decrease labor-consumption of diagnostics procedure and increase diagnostics efficiency.The method is based on comparison of duration of impulse periods picked up at primary transducers which are installed at transmission input and output. A signal picked up at a flywheel ring gear is taken as a reference signal.While selecting clearances of one and then the direction in speed-up - braking transmission regime changes in number of reference impulses at output provide data on angular clearance value in every gearing. As data are supplied registration and processing of results and forecasting of residual resource are to be done with the help of a program on the basis of realized algorithms for every gearing.Предложен способ диагностирования механических трансмиссий мобильных машин с применением вычислительной техники в целях снижения трудоемкости постановки диагноза, а также повышения оперативности.Способ основан на сопоставлении длительности периодов импульсов, снимаемых с первичных преобразователей, установленных на входе и выходе трансмиссии. В качестве опорного сигнала принимается сигнал, снимаемый с зубчатого венца маховика.В режиме «разгон - торможение» трансмиссии при выборе зазоров сначала одного, а затем другого направления изменение количества опорных импульсов в выходном дает информацию о величине углового зазора по каждому зубчатому зацеплению. Фиксирование и обработка результатов, а также прогнозирование остаточного ресурса по мере поступления информации происходят программно на основе реализованных алгоритмов для каждого зубчатого зацепления

    ВЛИЯНИЕ ПРОДОЛЖИТЕЛЬНОСТИ ХРАНЕНИЯ НА ОРГАНОЛЕПТИЧЕСКИЕ ПОКАЗАТЕЛИ КОНСЕРВИРОВАННЫХ ПЛОДОВ ТОМАТА

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    Preservation of tomatoes takes place by appropriate preparation of raw materials, packing in a container and sealing it with subsequent heat treatment. In the course of our studies on the suitability  of new varieties  for canning, we noted that all varieties  reacted differently  to heat treatment. For example, the forward variety, which has high taste qualities, had a sugar-acid index of 8,44,  compared to 7,04-7,51  in other varieties,  the tasting commission was estimated at 3,1-4,6 points, which is lower than other varieties, due to cracking of the skin of the fetus. After a year of storage, the sugar and acid index, depending on the variant, was 9,18-9,93, which indicates high taste qualities of the fruit. It was noted that the higher flavor qualities, regardless of the storage time, were in option 2.  For the varieties  Festive, Carat and Forward, the best was option 3. By the end of storage, it was 11,82 for the Festive variety, 10,51  for the variety Karat and 11,98  from Forward. According to the sugar-acid index of all the varieties studied, we distinguished Forward. We found that the sugar-acid index was higher than the taste, both before and after canning, in all varieties,  indicating  their high taste qualities. A higher score was given to variants 1 (control), 3 and 4. In variant 5, a sharper smell of garlic was noted.Консервирование плодов  томата   происходит путем  соответствующей подготовки сырья, закладки  в тару и ее герметизации с последующей тепловой  обработкой.  В процессе проведенных исследований на пригодность новых сортов для консервирования нами отмечено,  что все сорта по-разному реагировали на тепловую обработку. Так, сорт Форвард, отличающийся высокими вкусовыми качествами, имел сахаро-кислотный индекс 8,44, против 7,04-7,51 у других сортов, дегустационной комиссией был оценен в 3,1-4,6 балла, что ниже других сортов, из-за растрескивания кожицы плода. После года хранения сахаро-кислотный индекс в зависимости от варианта  составил   9,18-9,93, что указывает  на высокие  вкусовые  качества плодов.  Отмечено, что более высокие вкусовые качества независимо от продолжительности хранения были в варианте 2. Для сортов Праздничный,  Карат и Форвард лучшим оказался вариант 3. К концу хранения он составлял 11,82 у сорта Праздничный, 10,51 – у сорта Карат и 11,98 – у сорта Форвард. По сахарно-кислотному  показателю из всех изучаемых сортов выделился  сорт Форвард. Нами было установлено, что по вкусовым  качествам, как до консервирования, так и после у всех сортов сахаро-кислотный индекс был выше 7, что указывает на их высокие вкусовые качества. Более высокая оценка была дана вариантам 1 (контроль), 3 и 4. В варианте 5 отмечен более резкий запах чеснока

    Secreted Human Amyloid Precursor Protein Binds Semaphorin 3a and Prevents Semaphorin-Induced Growth Cone Collapse

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    The amyloid precursor protein (APP) is well known for giving rise to the amyloid-β peptide and for its role in Alzheimer's disease. Much less is known, however, on the physiological roles of APP in the development and plasticity of the central nervous system. We have used phage display of a peptide library to identify high-affinity ligands of purified recombinant human sAPPα695 (the soluble, secreted ectodomain from the main neuronal APP isoform). Two peptides thus selected exhibited significant homologies with the conserved extracellular domain of several members of the semaphorin (Sema) family of axon guidance proteins. We show that sAPPα695 binds both purified recombinant Sema3A and Sema3A secreted by transfected HEK293 cells. Interestingly, sAPPα695 inhibited the collapse of embryonic chicken (Gallus gallus domesticus) dorsal root ganglia growth cones promoted by Sema3A (Kd≤8·10−9 M). Two Sema3A-derived peptides homologous to the peptides isolated by phage display blocked sAPPα binding and its inhibitory action on Sema3A function. These two peptides are comprised within a domain previously shown to be involved in binding of Sema3A to its cellular receptor, suggesting a competitive mechanism by which sAPPα modulates the biological action of semaphorins

    Immune plexins and semaphorins: old proteins, new immune functions

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    Plexins and semaphorins are a large family of proteins that are involved in cell movement and response. The importance of plexins and semaphorins has been emphasized by their discovery in many organ systems including the nervous (Nkyimbeng-Takwi and Chapoval, 2011; McCormick and Leipzig, 2012; Yaron and Sprinzak, 2012), epithelial (Miao et al., 1999; Fujii et al., 2002), and immune systems (Takamatsu and Kumanogoh, 2012) as well as diverse cell processes including angiogenesis (Serini et al., 2009; Sakurai et al., 2012), embryogenesis (Perala et al., 2012), and cancer (Potiron et al., 2009; Micucci et al., 2010). Plexins and semaphorins are transmembrane proteins that share a conserved extracellular semaphorin domain (Hota and Buck, 2012). The plexins and semaphorins are divided into four and eight subfamilies respectively based on their structural homology. Semaphorins are relatively small proteins containing the extracellular semaphorin domain and short intra-cellular tails. Plexins contain the semaphorin domain and long intracellular tails (Hota and Buck, 2012). The majority of plexin and semaphorin research has focused on the nervous system, particularly the developing nervous system, where these proteins are found to mediate many common neuronal cell processes including cell movement, cytoskeletal rearrangement, and signal transduction (Choi et al., 2008; Takamatsu et al., 2010). Their roles in the immune system are the focus of this review

    The Unity of Microcosm and Macrocosm. A New Approach to the Solution of the Old World Outlook question

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    The article is dedicated to the examination of an ancient problem concerning the unity of microcosm and macrocosm. There is a new approach to its solution. It is based on the idea complementarity from the quantum physics, Curie principle (the principle of symmetry/dissymmetry) and on issues of the science of cerebral hemispheres («left brain, right brain»)

    Computer System For Diagnostics of Mobile Machinery Transmission

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    A new method for diagnostics of mechanical transmissions of mobile machinery is proposed in the paper. The method presupposes an application of computing equipment and its purpose is to decrease labor-consumption of diagnostics procedure and increase diagnostics efficiency.The method is based on comparison of duration of impulse periods picked up at primary transducers which are installed at transmission input and output. A signal picked up at a flywheel ring gear is taken as a reference signal.While selecting clearances of one and then the direction in speed-up - braking transmission regime changes in number of reference impulses at output provide data on angular clearance value in every gearing. As data are supplied registration and processing of results and forecasting of residual resource are to be done with the help of a program on the basis of realized algorithms for every gearing

    Berries and large fruits of the Samara region harvest 2016 year of the collection of the research institute «Zhigulevsky garden» as a perspective raw material in the food industry

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    One of the most important components of the human diet is the berries and stone fruits. They are rich in sugars, organic acids and biologically active substances - antioxidants. Together, the presented indicators (chemical composition and antioxidant activity) are important for the stable operation of the human body and the technological process when processing plant materials. When analyzing the chemical composition of berries and large fruits from the collection of the Research Institute "Zhigulevskie Gardens", it was revealed that the grade of raw materials influences the determined indexes.The highest value of soluble solids is occupied by the samples of apricot (leading Krugly variety), Black currant (leading Orloviya variety), raspberry (Balzam is leading).The lowest value of soluble solids was observed in strawberry varieties Kama. Analyze berries and fruits differ in the content of organic acids slightly. The maximum content of sugars in apricot, and the minimum for black currant. In the studied fruits, the highest content of phenols was recorded in the black currant. The varieties of flavonoids are different: strawberry Festivalaya, black currant Perun, apricot Khabarovskiy and raspberry Balzam. Low results showed apricot (grade Krugly, Pogremok). The high antioxidant activity was shown by the raspberry varieties Lyubetovskaya and Balzam. The chemical composition and antioxidant activity of fruits and berries play an important role not only for the human body, but also for the technological process during their processing. For this reason, analysis of the feedstock is an important stage in the development and manufacture of food products with a directed antioxidant effect

    EFFECT OF STORAGE DURATION FOR ORGANOLEPTIC INDICATORS OF CANNED TOMATOES

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    Preservation of tomatoes takes place by appropriate preparation of raw materials, packing in a container and sealing it with subsequent heat treatment. In the course of our studies on the suitability  of new varieties  for canning, we noted that all varieties  reacted differently  to heat treatment. For example, the forward variety, which has high taste qualities, had a sugar-acid index of 8,44,  compared to 7,04-7,51  in other varieties,  the tasting commission was estimated at 3,1-4,6 points, which is lower than other varieties, due to cracking of the skin of the fetus. After a year of storage, the sugar and acid index, depending on the variant, was 9,18-9,93, which indicates high taste qualities of the fruit. It was noted that the higher flavor qualities, regardless of the storage time, were in option 2.  For the varieties  Festive, Carat and Forward, the best was option 3. By the end of storage, it was 11,82 for the Festive variety, 10,51  for the variety Karat and 11,98  from Forward. According to the sugar-acid index of all the varieties studied, we distinguished Forward. We found that the sugar-acid index was higher than the taste, both before and after canning, in all varieties,  indicating  their high taste qualities. A higher score was given to variants 1 (control), 3 and 4. In variant 5, a sharper smell of garlic was noted
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