Association of endometrioid ovarian carcinoma arising from endometriosis, endometrioid endometrial carcinoma, and high-grade undifferentiated endometrial sarcoma. a case report

Endometriosis is a chronic disease that affects women of reproductive age. Malignant transformation in endometriosis is considered to be an unusual event, only occurring in 0.7-0.1% of cases. However the association between endometriosis and endometrial cancer is not well defined. Also in literature, rare cases of uterine sarcoma, about 3% of all uterine malignancies, associated with endometriosis have been reported. The authors report a case of a 47-years-old Italian woman with histologic diagnosis of endometrioid ovarian carcinoma arising from endometriosis, endometrioid endometrial carcinoma, and undifferentiated endometrial sarcoma. Therefore there have been few studies addressing the relationship between endometrial stromal sarcomas (ESS), and endometriosis. Novel scientific findings are necessary to investigate a possible common pathway and an effective treatment, although complete tumor resection can reduce the recurrence rate

Ovarian endometrioid adenocarcinoma diagnosed in pregnancy. a case report

The prevalence of adnexal masses pregnancy is about 0.19-8.8%. The malignancy rate is around 1-6%, and indeed most cases are benign masses. During pregnancy adnexal masses should be accurately evaluated to identify the patients who need surgery from those who need a 'wait-and-see' strategy. The authors report a case of 36-year-old woman (gravida 2, para 2, two vaginal deliveries) referred to the Gynecologic Department with diagnosis of endometrioid ovarian adenocarcinoma. The patient underwent laparotomic surgery with left salpingo-oophorectomy, total hysterectomy, pelvic and para-aortic lymphadenectomy, and peritoneal washing for optimal surgery staging. No ascites or residual tumour in the abdominal cavity were found macroscopically. Histopathology was negative for residual ovarian cancer. Currently the treatment and the management of ovarian cancer are not well established because scientific evidence is limited

Precise determination of muon and electromagnetic shower contents from shower universality property

We consider two new aspects of Extensive Air Shower development universality allowing to make accurate estimation of muon and electromagnetic (EM) shower contents in two independent ways. In the first case, to get muon (or EM) signal in water Cherenkov tanks or in scintillator detectors it is enough to know the vertical depth of shower maximum and the total signal in the ground detector. In the second case, the EM signal can be calculated from the primary particle energy and the zenith angle. In both cases the parametrizations of muon and EM signals are almost independent on primary particle nature, energy and zenith angle. Implications of the considered properties for mass composition and hadronic interaction studies are briefly discussed. The present study is performed on 28000 of proton, oxygen and iron showers, generated with CORSIKA 6.735 for $E^{-1}$ spectrum in the energy range log(E/eV)=18.5-20.0 and uniformly distributed in cos^2(theta) in zenith angle interval theta=0-65 degrees for QGSJET II/Fluka interaction models.Comment: Submitted to Phys. Rev.

Fluorescence and Hybrid Detection Aperture of the Pierre Auger Observatory

The aperture of the Fluorescence Detector (FD) of the Pierre Auger Observatory is evaluated from simulated events using different detector configurations: mono, stereo, 3-FD and 4-FD. The trigger efficiency has been modeled using shower profiles with ground impacts in the field of view of a single telescope and studying the trigger response (at the different levels) by that telescope and by its neighbours. In addition, analysis cuts imposed by event reconstruction have been applied. The hybrid aperture is then derived for the Auger final extension. Taking into account the actual Surface Detector (SD) array configuration and its trigger response, the aperture is also calculated for a typical configuration of the present phase.Comment: contribution to the 29th International Cosmic Ray Conference, Pune, India, 3-10 August 200

Protection of vaccine preventable diseases in a population of hiv-infected children: A 3 years prospective study

Human Immunodeficiency Virus (HIV) infected children have a 30–70% chance of being incompletely immunized and may not respond serologically with the same magnitude or durability as uninfected children. The aim of the study was to describe the rate of protective antibodies titre and the persistence of the response against four recommended vaccinations in HIV infected children and adolescents. A two-phase observational study was performed in which protective IgG antibodies to measles, mumps, rubella and hepatitis B were determined and monitored for 12 and 24 months, in 26 perinatally HIV-infected children. The rate of protection for rubella and hepatitis B was significantly lower in the HIV group compared to the control group (92% vs. 65% for rubella and 78.4% vs. 45.4% for hepatitis B; p < 0.05). Children who received primary vaccination after initiating combination antiretroviral therapy (cART) had a higher rate of response. Seronegative patients who received a booster dose of vaccine had a good immunological response. HIV infection is associated with a lower response to vaccines against rubella and hepatitis. The beginning of cART before vaccination may be associated with a better response. The evaluation of the serological response is crucial in children with HIV infection in order to evaluate the protection of vaccine preventable diseases

Gelatin tannate and tyndallized probiotics: a novel approach for treatment of diarrhea

Intestinal permeability impairment is implicated in many gastrointestinal (GI) diseases. Chronic diarrhea, defined as the presence of diarrhea for more than 3 weeks in adults and 2 weeks in children, requires a different diagnostic and therapeutic work-up than acute diarrhea. Gelatin tannate, by reducing the clinical activity of acute colitis and the proinflammatory effects of lipopolysaccharide (LPS), is emerging as a mucosal barrier protector

Ocorrencia e abundância de espécies de plantas ameaçadas de extinção no entorno do reservatório da UHE Barra Grande.

Modelos de ocorrência e abundância de espécies são ferramentas atuais que devem ser incorporadas na conservação da biodiversidade no entorno de reservatórios de usinas hidroelétricas, prevendo ou planejando ações necessárias para mitigar os impactos ambientais destes empreendimentos. Neste estudo, nossos objetivos foram: modelar a ocorrência e abundância de espécies de plantas ameaçadas de extinção, verificar a relação entre a ocorrência prevista e a abundância observada e avaliar se os modelos baseados em abundância são mais eficientes em predizer a ocorrência do que aqueles baseados em dados de ocorrência (0/1). Representantes individuais de nove espécies (Araucaria angustifolia (Bertol.) Kuntze (Araucariaceae), Butia eriospatha (Mart. ex Drude) Becc. (Arecaceae), Clethra scabra Pers. (Clethraceae), Dicksonia sellowiana (Presl.) Hook. (Dicksoniaceae), Erythrina falcata Benth. (Fabaceae), Maytenus ilicifolia (Schrad.) Planch. (Celastraceae), Myrocarpus frondosus Allemão (Fabaceae), Podocarpus lambertii Klotzsch ex Endl. (Podocarpaceae) e Trithrinax brasiliensis Mart (Arecaceae)) foram contados em 388 parcelas (10x50m) aleatoriamente alocadas e georreferenciadas no entorno do reservatório da UHE Barra Grande (SC/RS). Modelamos sua relação com 15 variáveis ambientais utilizando dados de ocorrência (GLM) e abundância (Modelos Hurdle e Zero-inflado). Em geral, os modelos de ocorrência foram mais precisos do que os modelos de abundância. Para todas as espécies, a abundância observada foi correlacionada com a probabilidade de ocorrência, sugerindo que estudos futuros poderiam utilizar esta informação, em vez da abundância. Reconstruir padrões de abundância e de ocorrência é uma importante ferramenta para o planejamento de ações de conservação e manejo de espécies ameaçadas, permitindo que sejam indicadas as melhores áreas para a coleta e reintrodução de germoplasma vegetal ou mesmo a escolha de áreas de conservação com maior probabilidade de manter populações viáveis