The Interaction of Age, Gender, and Race/Ethnicity on Juvenile Justice Decision Making in Nebraska: The Comparisons of White, Black, Hispanic, and Native American

Although most research shows that the primary determinants of sentencing outcomes are the legally relevant factors such as the seriousness of the offense and prior criminal record, there is a substantial body of research examining the relationship between extra-legal factors (e.g. race, age, and gender), and sentencing outcomes. Most studies focus on direct effects of extra-legal factors on juvenile justice decision making rather than the interactions among them. The present study pursued two main goals: (1) testing the direct effects of age, gender, and race/ethnicity on juvenile justice decision making across four racial groups, and (2) exploring the interactive effects of three extra-legal variables on juvenile justice decisions. Regarding the direct effects of three extra-legal factors on outcomes, consistent with the previous studies, this study found that non-white youths were treated more harshly than white youths at the detention, petition, and disposition stages of the process. In addition, female youths were treated more leniently than male youths at petition and disposition decisions. On the other hand, the results regarding the effect of age were inconsistent. With regard to the interactive effects of age, and race/ethnicity on juvenile justice decisions using the disaggregated data by gender, older black males were treated more harshly than the other age-race categories at petition and disposition decisions. Moreover, younger white females were treated more leniently than the other age-race categories at the petition decision. Finally, this study reveals that older black males were treated more harshly than the other age-gender-race/ethnicity categories at the petition and disposition decisions

Key Strains, Anger and Delinquency: The General Strain Theory Test on Sourth Korean Youths From Low-Income Households

General Strain Theory: Negative relations of strains create unpleasant emotions (e.g., anger and depression), which lead strained people to commit crimes as their coping methods. Strains are more likely to lead to crimes

A Distributed Inference System for Detecting Task-wise Single Trial Event-Related Potential in Stream of Satellite Images

Brain-computer interface (BCI) has garnered the significant attention for their potential in various applications, with event-related potential (ERP) performing a considerable role in BCI systems. This paper introduces a novel Distributed Inference System tailored for detecting task-wise single-trial ERPs in a stream of satellite images. Unlike traditional methodologies that employ a single model for target detection, our system utilizes multiple models, each optimized for specific tasks, ensuring enhanced performance across varying image transition times and target onset times. Our experiments, conducted on four participants, employed two paradigms: the Normal paradigm and an AI paradigm with bounding boxes. Results indicate that our proposed system outperforms the conventional methods in both paradigms, achieving the highest $F_{\beta}$ scores. Furthermore, including bounding boxes in the AI paradigm significantly improved target recognition. This study underscores the potential of our Distributed Inference System in advancing the field of ERP detection in satellite image streams

Yoga Training Improves Metabolic Parameters in Obese Boys

Yoga has been known to have stimulatory or inhibitory effects on the metabolic parameters and to be uncomplicated therapy for obesity. The purpose of the present study was to test the effect of an 8-week of yoga-asana training on body composition, lipid profile, and insulin resistance (IR) in obese adolescent boys. Twenty volunteers with body mass index (BMI) greater than the 95th percentile were randomly assigned to yoga (age 14.7±0.5 years, n=10) and control groups (age 14.6±1.0 years, n=10). The yoga group performed exercises three times per week at 40~60% of heart-rate reserve (HRR) for 8 weeks. IR was determined with the homeostasis model assessment of insulin resistance (HOMA-IR). After yoga training, body weight, BMI, fat mass (FM), and body fat % (BF %) were significantly decreased, and fat-free mass and basal metabolic rate were significantly increased than baseline values. FM and BF % were significantly improved in the yoga group compared with the control group (p\u3c0.05). Total cholesterol (TC) was significantly decreased in the yoga group (p\u3c0.01). HDL-cholesterol was decreased in both groups (p\u3c0.05). No significant changes were observed between or within groups for triglycerides, LDL-cholesterol, glucose, insulin, and HOMA-IR. Our findings show that an 8-week of yoga training improves body composition and TC levels in obese adolescent boys, suggesting that yoga training may be effective in controlling some metabolic syndrome factors in obese adolescent boys

Mammary gland tumors in a male Cocker Spaniel

Background Mammary gland tumors are the most common tumors in sexually intact female dogs; however, they are rare in male dogs. This study was conducted to investigate the relationship between sexual hormones and mammary gland tumors in a male dog. Case presentation A 13-year-old, intact male Cocker Spaniel presented to the Veterinary Teaching Hospital of Kangwon National University, Republic of Korea, with an acute right ruptured caudal abdominal mass. Physical examination revealed a 14 × 14 cm ruptured mass in the right caudal abdomen, as well as a 1.5 × 1.5 cm mass in the first right mammary gland. The estrogen and progesterone concentrations in serum were within normal levels. Total mastectomy was done on the right side mammary glands. Following surgery, the site was fully recovered; however, a mass that had grown to 2 × 2 cm was found in the left fifth mammary gland and a testis tumor was also found over the period of 4 months. Mastectomy was performed on the left caudal mammary gland and castration was also performed. After the final surgery, the dog fully recovered. Histopathological examination of all three masses revealed high grade mammary adenocarcinoma in the mammary gland and the testis was diagnosed as Leydig cell adenoma. Immunohistochemical analysis revealed that the estrogen and progesterone receptors were expressed on limited cells in mammary and testis tumors. Conclusion The results of this study suggest that mammary tumors and testes tumors can occur in male dogs without relationship to female sexual hormone

Treatment strategy for papillary renal cell carcinoma type 2: a case series of seven patients treated based on next generation sequencing data

Background: Papillary renal cell carcinoma type 2 (PRCC2) is refractory to systemic treatment and has a dismal prognosis. Previous studies showed that genetic alterations in PRCC2 were heterogeneous regardless of germline or somatic mutations. In this study, we aimed to perform precision treatment of PRCC2 based on genetic information. Methods: We performed exome and genome sequencing of tumor tissues and matched normal samples. Based on sequencing data, we treated patients with metastatic PRCC2 using precision oncology. Results: Four patients underwent curative surgery of PRCC2 and three patients had metastatic PRCC2. All PRCC2 heterogeneously harbored own driver mutations. Two out of the three patients with metastatic disease had fumarate hydratase (FH) germline mutations. One patient with a germline FH mutation was diagnosed with hereditary leiomyomatosis RCC. He was treated with bevacizumab and erlotinib combination and showed a durable response. The other metastatic PRCC2 patient harboring a germline FH mutation had an additional somatic FH mutation and was durably controlled with pazopanib. Other metastatic PRCC2 patient with somatic PBRM1 and SETD2 mutations had over 5 years of overall survival with axitinib treatment. Conclusions: We performed precision systemic treatment based on genetic information. Genome sequencing could help identify candidates for targeted therapy in PRCC2, a genetically heterogeneous disease

Clinical outcomes and prognostic factors in patients with breast diffuse large B cell lymphoma; Consortium for Improving Survival of Lymphoma (CISL) study

<p>Abstract</p> <p>Background</p> <p>The breast is a rare extranodal site of non-Hodgkin lymphoma, and primary breast lymphoma (PBL) has been arbitrarily defined as disease localized to one or both breasts with or without regional lymph nodes involvement. The aim of this study was to evaluate the clinical outcomes in patients with diffuse large B cell lymphoma (DLBCL) and breast involvement, and to find the criteria of PBL reflecting the outcome and prognosis.</p> <p>Methods</p> <p>We retrospectively analyzed data from 68 patients, newly diagnosed with DLBCL and breast involvement at 16 Korean institutions between January 1994 and June 2009.</p> <p>Results</p> <p>Median age at diagnosis was 48 years (range, 20-83 years). Forty-three (63.2%) patients were PBL according to previous arbitrary criteria, sixteen (23.5%) patients were high-intermediate to high risk of international prognostic index. The patients with one extranodal disease in the breast (OED) with or without nodal disease were 49 (72.1%), and those with multiple extranodal disease (MED) were 19 (27.9%). During median follow-up of 41.5 months (range, 2.4-186.0 months), estimated 5-year progression-free survival (PFS) was 53.7 ± 7.6%, and overall survival (OS) was 60.3 ± 7.2%. The 5-year PFS and OS was significantly higher for patients with the OED group than those with the MED group (5-year PFS, 64.9 ± 8.9% vs. 27.5 ± 11.4%, p = 0.001; 5-year OS, 74.3 ± 7.6% vs. 24.5 ± 13.0%, p < 0.001). In multivariate analysis, MED (hazard ratio [HR], 3.61; 95% confidence interval [CI], 1.07-12.2) and fewer than four cycles of systemic chemotherapy with or without local treatments (HR, 4.47; 95% CI, 1.54-12.96) were independent prognostic factors for worse OS. Twenty-five (36.8%) patients experienced progression, and the cumulative incidence of progression in multiple extranodal sites or other than breasts and central nervous system was significantly different between the OED group and the MED group (5-year cumulative incidence, 9.7 ± 5.4% vs. 49.0 ± 15.1%, p = 0.001).</p> <p>Conclusions</p> <p>Our results show that the patients included in OED group, reflecting different treatment outcome, prognosis and pattern of progression, should be considered as PBL in the future trial. Further studies are warranted to validate our suggested criteria.</p

Is fear of crime splitting the sister cities? The case of Los Dos Laredos

This article describes the change in border dynamics of the Laredo-Nuevo Laredo U.S.-Mexican border during the first decade of the 21st century. While the sharing and blending of cultures has long been considered an integral part of the regional identity, publicity related to crime in Mexico and fear of the potential for spillover crime has created a significant degree of separation between the two communities that once lived as one. In terms of social construction of place, the Rio Grande boundary separating the sister cities was relatively meaningless for many years as laborers, shoppers and tourists crossed easily between the two nations. The integrated cultural bond has moved towards a coexistence favoring growth in the Laredo economy while Nuevo Laredo struggles. © 2012 Elsevier Ltd