The registration and the processing of signals of geomagnetic pulsations in the system of the geodynamic monitoring

Annotation: In this paper, methods of the implementing filtering are considered for recording of irregular disturbances of the geomagnetic field. The solution of problems of the processing of signals is considered for the system of the geodynamic control. They are based on the detection of the informative area of the registration in real time and the localization of the spatial location of the source of geomagnetic disturbances on the base of the regression analysis. It is noted that methods of simultaneous formation of borders of the bands of HPF and LPF necessary to use with the technical implementation of multi-band filtering. It allows to obtain the absolutely exact conjugation of frequency borders of neighboring subbands of filter, and also to reduce the number of tunable passive elements. Determined that in the technical implementation of the approach, obtaining an arbitrary phase-frequency characteristic that is not related to the amplitude-frequency response, and ensuring the stability of a multi-band filter of high order is important. Application of the regression analysis for selection and an assessment of parameters of distribution of geomagnetic pulsations at magnetotelluric sounding give the chance to consider features of use in system of monitoring of multirange filters and algorithms of spectral timing analysis.Keywords: geomagnetic field, disturbance, registration, processing, signal, geodynamic, monitoring, magnetotelluri

Effects of Primary Stored Energy on Relaxation Behavior of High Entropy Bulk Metallic Glasses Under Compressive Elastostatic Loading

This paper aims to show the effects of primary stored energy in high entropy bulk metallic glasses (HE-BMGs) on their relaxation behavior after elastostatic loading process. For this purpose, three HE-BMGs with different chemical compositions and primary stored energy were fabricated. Differential scanning calorimetry and nanoindentation tests were carried out to evaluate the relaxation enthalpy and microscopic mechanical characterization of alloys. The results showed that increase in the number of element types in the alloying composition leads to the increment of stored energy and structural heterogeneity in the primary alloys. Moreover, the elastostatic loading rejuvenates the primary alloys; however, an optimum heterogeneity is needed for the maximum structural heterogeneity and stored energy in the glassy alloy. The hardness measurements also indicate that the elastostatic loading intensifies the hardness variations in the alloys, which may be due to the increased structural heterogeneity

Anti-inflammatory effect of functionalized sulfasalazine boron nitride nanocages on cardiovascular disease and breast cancer: An in-silico simulation

The objective of this research work is to investigate the ability of sulfasalazine (as an anti-cytokine drug) functionalized B16N16, B15GeN16 and B15SiN16 nanocages to treat inflammatory cardiovascular disease and breast cancer in comparison with the pure sulfasalazine (SSZ). Density functional theory (DFT) calculations at PBE1 functional were used to investigate the structural, electronic and spectral properties of sulfasalazine decorated B16N16, B15GeN16 and B15SiN16 nanocages. The most stable state was obtained on adsorption of SSZ over B16N16, B15GeN16 and B15SiN16 nanocages via its pyridine ring. Also, the adsorption of SSZ through SO2 group over B16N16, B16GeN16 and B16SiN16 nanocages causes the lower binding energy and the increment of dipole moment as both factors can lead to increased sensitivity of the B16GeN16 nanocage to the drug. Molecular docking simulation illustrates that the interaction of SSZ via its pyridine ring with B15GeN16 gives the best binding affinity and inhibition potential of HER2 (human epidermal growth factor receptor 2) and TNF-α (tumor necrosis factor-alpha) whereas interaction of -SO2 group with B16N16 gives the best binding affinity and inhibition potential of COX-2 (cyclooxygenase-2) and IL-1 (Interleukin-1) receptors. The predicted results demonstrated that SSZ/B16N16 and SSZ/B16GeN16 complexes can serve as a promising and preventive agent for inflammatory cardiovascular disease and breast cancer. © 2022 Elsevier B.V