Evaluation of the efficiency of perioperative chemotherapy in the complex treatment of gastric cancer

The aim of the study is to study the effectiveness of perioperative chemotherapy in the treatment of gastric cancer and its direct effect on the results of surgical treatmentЦелью исследования является изучение эффективности периоперационной химиотерапии при раке желудка и ее непосредственного влияния на результаты хирургического лечени

Social Network-Based Digital Stroke Prevention: Opportunities, Results and Prospects

Aim. To study the possibilities and limitations of the social network as a digital medical tool, which is aimed at improving programs for primary and secondary stroke prevention in young people.Material and methods. The study was carried out in the format of online training for volunteers. At the first stage of the work, the online school “Stroke in Young People” was announced in 8 medical blogs. As part of the school, a special account was created for readers (n=1354). At the second stage, 49 respondents (4% of men, whose average age was 24.4±5.2 years) were selected from 1354 listeners, who were surveyed on “Awareness of risk factors and stroke symptoms among users of social networks” before and after the online school.Results. The online school audience is predominantly female (91%), and 43% of readers were in the 25-34 age group. The total number of people who listened to and read the online school material is 8712 people. 17% worked in the healthcare system, and 22% of respondents had a history of stroke. 38 (78%) people of the 2nd stage among the respondents independently searched for information about stroke earlier, and 30 (61%) received this information passively from medical workers in 2020. Before the online school start, the majority of respondents (over 60%) were aware of 2 out of 7 stroke risk factors (dyslipidemia and arterial hypertension) and 3 out of 6 stroke signs (drooping of the face half, weakness in the limbs and difficulty speaking). Less than 40% of the participants considered the stroke risk factors for diabetes mellitus, other cardiovascular diseases (CVD), obesity, and alcohol use; less than 20% were aware of stroke symptoms such as impaired vision and coordination and very severe headache. After completing online learning, the greatest increase in knowledge was found among the following risk factors – smoking and other CVDs (p<0.05); stroke symptoms - headache and drooping of the face half (p<0.05).Conclusion. The online school aroused interest among healthcare workers and people without medical education, including those with stroke. Most of the respondents believed that they knew how to prevent a stroke (over 80%) and would be able to provide first aid to a person with a stroke (over 90%). At the same time, the awareness of risk factors and stroke symptoms was low prior to the start of learning, even though the study included healthcare workers and stroke survivors. Online learning has led to increased awareness of some risk factors and stroke symptoms. Social media can be one of the tools for medical prevention of stroke in young people, but program planning should take into account the way the material is presented and its readability

PARODONT-PROTECTIVE ACTION OF ORAL GEL "ARGININE" APPLICATIONS IN RATS WITH INTESTINAL DYSBIOSIS WHICH RECEIVED A HIGH-FAT DIET

Borisenko A. V., Levitsky A. P., Kuvaev A. S. Пародонтопротекторное действие оральных аппликаций геля «Аргинин» у крыс с кишечным дисбиозом, получавших высокожировой рацион = Parodont-protective action of oral gel "Arginine" applications in rats with intestinal dysbiosis which received a high-fat diet. Journal of Education, Health and Sport. 2015;5(3):294-302. ISSN 2391-8306. DOI: 10.5281/zenodo.16495 http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%283%29%3A294-302 https://pbn.nauka.gov.pl/works/552270 http://dx.doi.org/10.5281/zenodo.16495 Formerly Journal of Health Sciences. ISSN 1429-9623 / 2300-665X. Archives 2011 – 2014 http://journal.rsw.edu.pl/index.php/JHS/issue/archive   Deklaracja. Specyfika i zawartość merytoryczna czasopisma nie ulega zmianie. Zgodnie z informacją MNiSW z dnia 2 czerwca 2014 r., że w roku 2014 nie będzie przeprowadzana ocena czasopism naukowych; czasopismo o zmienionym tytule otrzymuje tyle samo punktów co na wykazie czasopism naukowych z dnia 31 grudnia 2014 r. The journal has had 5 points in Ministry of Science and Higher Education of Poland parametric evaluation. Part B item 1089. (31.12.2014). © The Author (s) 2015; This article is published with open access at Licensee Open Journal Systems of Kazimierz Wielki University in Bydgoszcz, Poland and Radom University in Radom, Poland Open Access. This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. This is an open access article licensed under the terms of the Creative Commons Attribution Non Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non commercial use, distribution and reproduction in any medium, provided the work is properly cited. The authors declare that there is no conflict of interests regarding the publication of this paper. Received: 20.01.2014. Revised 27.02.2015. Accepted: 12.03.2015.   УДК 616.33+342.092       ПАРОДОНТОПРОТЕКТОРНОЕ ДЕЙСТВИЕ ОРАЛЬНЫХ АППЛИКАЦИЙ ГЕЛЯ «АРГИНИН» У КРЫС С КИШЕЧНЫМ ДИСБИОЗОМ, ПОЛУЧАВШИХ ВЫСОКОЖИРОВОЙ РАЦИОН   Parodont-protective action of oral gel "ARGININE" applications in rats with intestinal dysbiosis which received a high-fat diet   А. В. Борисенко1, А. П. Левицкий2, А. С. Куваев1 A. V. Borisenko, A. P. Levitsky, A. S. Kuvaev   1Киевский национальный медицинский университет им. А. А. Богомольца 2ГУ «Институт стоматологии НАМН» (г. Одесса)   1National Medical University named after А. А. Bogomolets, Kiyv 2SE “The Institute of Stomatology of the NAMS of Ukraine” (Odessa, Ukraine)   Abstract   Aim: To determine the periodontal condition at intestinal dysbiosis and high-fat diet (HFD) and the influence of an oral gel containing arginine. Materials and methods: We used a mucous-adhesive phytogel containing cardioarginin (14% on a 4% CMC). Intestinal dysbiosis was obtained using lincomycin (60 mg/kg). HFD was prepared by addition of palm oil to the feed (final fat content in the diet 25%). Dysbiosis was calculated according to the levels of urease and lysozyme, inflammation was expressed in terms of inflammatory markers (MDA and elastase). In the gums there were determined the content of hyaluronic acid and the degree of atrophy of periodontal by Nikolaeva. Gel applications were performed at the dose 0.3 ml / rat daily. Results: Intestinal dysbiosis on the HFD background causes in the development of periodontal dysbiosis, inflammation and tissue recession. Oral gels containing arginine have parodont-protective action.   Key words: periodontal, dysbiosis, fatty food, inflammation, arginine, oral gels.   Реферат   При воспроизведении кишечного дисбиоза на фоне высокожирового рациона в пародонте крыс развивается дисбиоз, воспаление и рецессия тканей. Оральные аппликации геля, содержащего аргинин, оказывают пародонтопротекторное действие, что свидетельствует о важной защитной роли окиси азота, образующейся из аргинина.   Ключевые слова: пародонт, дисбиоз, жировое питание, воспаление, аргинин, оральные гели. ьные гели

Thrombocytopenia in HIV-infection

Determination of the number of platelets in HIV-infected people who applied in the Samara Regional Center for Prevention and Control of AIDS and infectious diseases. Thrombocytopenia was detected in 79%, severe in 23,1%. It was recorded at any stage of HIV infection and correlated with the level of CD4 lymphocytes. 45 patients was performed sternal puncture. Morphological evaluation of bone marrow showed changes in 87% of HIV-infected The most common violation was the low content or absence of megakaryocytes in bone marrow (72,5%)