Conformation of surface exposed N-terminus part of bacteriorhodopsin studied by transferred NOE technique

AbstractInteraction of the monoclonal antibody A5 raised against native bacteriorhodopsin (BR) with the synthetic peptide pGlu1-Ala-Gln-Ile-Thr-Gly-Arg7-NH2, corresponding to the amino acid sequence 1–7 was studied by transferred nuclear Overhauser effect (TRNOE) spectroscopy. The denaturing reagents and the specially designed pulse sequences which eliminate broad signals from the TRNOE spectra were used to favour evaluation of the TRNOE peaks. On the basis of the data obtained, the conformation of peptide bound with A5 was calculated. A model of the mutual arrangement of bacteriorhodopsin N-terminus and the first transmembrane α-helical segment 8–32 was proposed

Abstracts from the 20th International Symposium on Signal Transduction at the Blood-Brain Barriers

https://deepblue.lib.umich.edu/bitstream/2027.42/138963/1/12987_2017_Article_71.pd

Whispering-gallery modes in shielded hemispherical dielectric resonators

The results of the numerical and experimental investigations of whispering-gallery (WG) modes in shielded hemispherical dielectric resonators are presented in this paper. It is shown that the Q factor of WG modes in the shielded resonator can be ten times much higher than the Q factor of the similar open hemispherical dielectric-resonator modes. Shielding the resonator can decrease the dimensions of both the dielectric hemisphere and resonator as a whole, saving the high-Q factor of WG modes. The usage of a cylindrical shield and local flat reflectors in the experiment provides the investigation of the high-Q factor of WG modes in the resonator

Analysis of Images, Social Networks and Texts

International audienc

Hyperon signatures in the PANDA experiment at FAIR

We present a detailed simulation study of the signatures from the sequential decays of the triple-strange pbar p -> Ω+Ω- -> K+ΛbarK- Λ -> K+pbarπ+K-pπ- process in the PANDA central tracking system with focus on hit patterns and precise time measurement. We present a systematic approach for studying physics channels at the detector level and develop input criteria for tracking algorithms and trigger lines. Finally, we study the beam momentum dependence on the reconstruction efficiency for the PANDA detector