Ko-infeksi asimptomatik helminthiasis pada pasien tuberkulosis paru di Surabaya kota: studi pendahuluan

BACKGROUNDPulmonary tuberculosis (TB) is a leading cause of morbidity and mortality, and East Java province is the second largest contributor of co-infection in Indonesia. Asymptomatic helminth infection among pulmonary tuberculosis patients causes another public health problem. Few data relate to helminth infection based on clinical and immunological outcomes of pulmonary TB in highly endemic areas. METHODSThis study was designed as a preliminary study and aimed to determine helminth co-infection among TB patients with a macroscopic assessment. This cross-sectional study was conducted in June-August 2017. RESULTSAmong 16 treated active TB patients from TB cohort data of Tanakali Kedinding health center found that 56% were stool smear-positive for Trichuris trichiura eggs, but had no clinical symptoms. CONCLUSIONWhether or not the helminth infection may have an impact on the diagnosis and treatment of active TB remains to be further investigated. Co-infection could be inhibited by the host immune response and improve the prognosis of TB treatment.LATAR BELAKANGPenyakit tuberculosis paru (TB) hingga saat ini masih menjadi penyebab utama tingginya angka morbiditas dan mortalitas, dan propinsi Jawa Timur termasuk penyumbang penderita kedua terbanyak di Indonesia. Hanya sedikit data informasi diketahui terkait infeksi kecacingan yang terjadi pada penderita TB baik secara klinis dan imunologi pada daerah endemis. METODEStudi ini di desain sebagai studi awal dan bertujuan untuk menilai ko-infeksi kecacingan diantara penderita TB. Studi potong-lintang ini dilakukan pada bulan Juni-Agustus 2017.HASILEnam belas penderita aktif TB berdasarkan data kohort tuberkulosis Puskesmas Tanakali Kedinding, didapatkan 56%-nya positif kecacingan dengan ditemukannya telur Trichuris trichiura.KESIMPULANWalaupun efek dari infeksi kecacingan tidak berdampak terhadap diagnosis dan pengobatan tuberkulosis, akan tetapi sebaiknya penderita yang terdeteksi sebagai tuberkulosis aktif, dilakukan skrining kecacingan terlebih dahulu. Ko-infeksi dapat dihampat oleh respon imun penderita dan meningkatkan prognosis pengobatan tuberkulosis.&nbsp

ANGKA KEJADIAN KO-INFEKSI HELMINTH PADA PASIEN TUBERKULOSIS PARU DI PUSKESMAS TANAKALI KEDINDING SURABAYA

Tuberculosis is still one of the causes of mortality and morbidity in the world, including in Indonesia. East Java is the second largest contributor for TB patient. One of the risk factors of TB is the socioeconomic problems as a result of poverty. Poverty in endemic areas are also associated with an increase incidence of tropical infections such as helminths. The purpose of this study was to determine the prevalence rate of co-infection helminthiasis in patients with pulmonary TB. The research is a descriptive study. The data taken is primary data through interviews with questionnaires and laboratory tests with direct fecal smear. Co-infection is influenced by several internal factors that include the data characteristics, medical history, and behavior, as well as external factors such as environmental sanitation home.The research variables are data characteristics, medical history, behavior, and the environment sanitation. The sample used in study is 17 patients with active tuberculosis treatment in Puskesmas Tanakali Kedinding. The largest age group of TB patients are aged <60 years (75%) with the largest gender is male (56%). 56.3% of patients had health insurance non-BPJS and 56.2% had no history of BCG immunization. 43.75% patients are recurrent TB patients. To score the environment, 62% are still poor and a score of 75% is still bad behavior. Under microscopic examination, sixteen subjects were checked and result was 100% negative. From the results of this study concluded that there is no coinfection of helminth in TB patients from Puskesmas Tanakali Kedinding Surabaya