Alat Deteksi Kebocoran Gas Rumah Tangga Berbasis Internet of Things

Teknologi yang berkembang pesat menghasilkan inovasi-inovasi baru yang mampu membantu memudahkan pekerjaan manusia. Dan saat ini semua informasi dapat diakses dengan mudah dan cepat dan menghasilkan data yang akurat. Inilah salh satu konsep dari Internet of thins, yaitu segala hal yang terhubung dengan internet. Dari sinilah ide awal tersebut muncul. Dengan adanya kasus kebakaran rumah yang disebabkan oleh kebocoran gas rumah tangga. Maka terciptalah alat ini, yang bekerja dengan memanfaatkan jaringan dari internet. Alat ini mampu ngirimkan sinyal ke telepon pintar (smartphone) kita, saat terjadi kebocoran gas rumah tangga

UPAYA MENINGKATAN HASIL BELAJAR SISWA MELALUI METODE PEMBELAJARAN JIGSAW DENGAN MATERI BAGIAN-BAGIAN TUMBUHAN MATA PELAJARAN IPA KELAS IV SDN GUNUNGCUPU 2

Tujuan utama penelitian ini adalah untuk mengetahui penerapan model pembelajaran jigsaw terhadap peningkatan hasil belajar IPA pada siswa kelas IV SDN Gunungcupu 2 Kecamatan Cimanuk. Jenis Penelitian ini merupakan penelitian tindakan (action research), penelitian dilakukan untuk memecahkan masalah pembelajaran di kelas. Rancangan penelitian Sesuai dengan jenis penelitian yang dipilih, yaitu penelitian tindakan, Hasil penelitian menunjukkan bahwa pembelajaran IPA dengan metode jigsaw memiliki dampak positif dalam meningkatkan hasil belajar siswa. Hal ini dapat dilihat dari semakin mantapnya pemahaman dan penguasaan siswa   terhadap materi yang telah disampaikan guru. Peningkatan hasil belajar siswa terhadap mata pelajaran IPA tersebut tergambar pada tindakan Siklus I mengalami peningkatan sebesar 5,00% yaitu dari 59,29 pada pra-tindakan menjadi 64,29 pada siklus I, dan pada siklus II mengalami peningkatan sebesar 23,57%, yaitu dari 64,29 dari siklus I menjadi 87,86 pada siklus II. Dengan demikian penerapan metode jigsaw dapat meningkatkan prestasi siswa kelas IV SDN Gunungcupu 2 Kecamatan Cimanuk.

2-(3-(chloromethyl)benzoyloxy)benzoic Acid Increases CD4+ Regulatory T-Cell Population and FoxP3 Expression in Lipopolysaccharide-induced Mice

BACKGROUND: Lipopolysaccharide (LPS) has been reported to increase CD4+ regulatory T-cell (CD4+ Treg) populations. Acetylsalicylic acid (ASA) has been reported to have immunomodulatory activity, but it may induce chronic gastric ulceration. Another salicylic acid-bearing compound, 2-(3-(chloromethyl)benzoyloxy)benzoic acid (3-CH2Cl), has been reported to have less gastric mucosal damage. However, the effect of 3-CH2Cl on CD4+ Tregs in LPS-induced mice is still unknown. Therefore, the present study was conducted to investigate the immunomodulatory effect of 3-CH2Cl on CD4+ T-cell and CD4+ Treg populations as well as FoxP3 expression in LPS-induced mice. METHODS: Synthesis of 3-CH2Cl was performed by mixing salicylic acid and chloromethylbenzoylchloride with the catalyzation of pyridine, acetone and heat. The 3-CH2Cl tablets were prepared using direct compression method. After intraperitoneal injection of 1 mg/kg BW LPS to mice, 60 mg/kg BW ASA or 60 mg/kg BW 3-CH2Cl was given orally for 3 days. The splenocyte was obtained through splenectomy and collagenase digestion. The population of CD4+ T-cells and CD4+ Tregs, as well as the splenic FoxP3 expression were determined using flow cytometry technique. RESULTS: CD4+ T-cell populations in mice treated with LPS and 3-CH2Cl or ASA were lower than those treated with LPS merely. Meanwhile, CD4+ Treg populations and FoxP3 expression levels in mice treated with LPS and 3-CH2Cl or ASA were higher than those treated with LPS merely. CONCLUSION: Since 3-CH2Cl could decrease CD4+ T-cell population and increase CD4+ Treg population mediated by the increase of FoxP3 expression in LPS-induced inflammation, it may act as a potential therapeutic drug to reduce inflammatory conditions. KEYWORDS: 2-(3-(chloromethyl)benzoyloxy)benzoic acid, acetylsalicylic acid, CD4, T-regulatory cells, FoxP3, LP

Proceedings of the 3rd International Conference on Community Engagement and Education for Sustainable Development

This proceeding contains articles on the various ideas of the academic community presented at The 3rd International Conference on Community Engagement and Education for Sustainable Development (ICCEESD 2022) organized by the Universitas Gadjah Mada, Indonesia on 7th-8th December 2022.  ICCEESD is a biannual forum for sharing, benchmarking, and discussing HEI’s activities in developing Education for Sustainable Development towards community engagement. Education for Sustainability as a teaching strategy for resolving community challenges through formal, informal, or non-formal education is expected to benefit from various community service best practices by academics, researchers, and students. The 3rd ICCEESD has “Strengthening Education for Sustainability Towards Better Community Engagement” as its theme this year. It is expected that the 3rd ICCEESD will provide a forum for the presenters and participants to exchange best practices, policies, and conceptual implementation of Education for Sustainability towards better community engagement and explore ideas to address community needs.  Conference Title: 3rd International Conference on Community Engagement and Education for Sustainable DevelopmentConference Theme: Strengthening Education for Sustainability Towards Better Community EngagementConference Acronyms: ICCEESD 2022Conference Date: 7th-8th December 2022Conference Location: Grand Rohan Jogja Yogyakarta, IndonesiaConference Organizer: Universitas Gadjah Mada, Indonesi