17 research outputs found
New Efficient Route to Dissymmetric 2,4-Di(het)aryl-pyrido[3,2-d]pyrimidines via Regioselective Cross-Coupling Reactions
No full textA New Catalytic Cross-Coupling Approach for the Synthesis of Protected Aryl and Heteroaryl Amidines
No full text
Pyridines from azabicyclo[3.2.0]hept-2-en-4-ones through a proposed azacyclopentadienone
Get PDFPyridines have been formed by heating azabicyclo[3.2.0]hept-2-en-4-ones in toluene. The generation of a 3-azacyclopentadienone intermediate via a [2+2]-cycloreversion is proposed as the key step. A Diels-Alder reaction of a styrene, extrusion of carbon monoxide and loss of hydrogen then gives the pyridine. The process parallels the well-known synthesis of benzenes from cyclopentadienones. The azabicyclo[3.2.0]hept-2-en-4-ones were synthesized from the reaction between readily available cyclopropenones and 1-azetines, in which the cyclopropenones behave as all-carbon 1,3-dipolar equivalents
Pd-Catalyzed Cross-Coupling of Functionalized Organozinc Reagents with Thiomethyl-Substituted Heterocycles
No full textPalladium-Catalyzed, Copper(I)-Mediated Coupling of Boronic Acids and Benzylthiocyanate. A Cyanide-Free Cyanation of Boronic Acids
No full text
Palladium(0)-Catalyzed, Copper(I)-Mediated Coupling of Boronic Acids with Cyclic Thioamides. Selective Carbon-Carbon Bond Formation for the Functionalization of Heterocycles
No full textAccess and Regioselective Transformations of 6-Substituted 4-Aryl-2,8-dichloropyrido[3,2- d
No full text
