Agora Teaching App

Professional development of teachers normally ends after formal collegiate education. Agora desires to help educators continually train, to learn the skills of good teaching in classrooms by using various, non-traditional methodologies. By translating Agoras current platform to an app, Agora can widen their scope and serve Latin American countries outside of Peru, where they are currently based. We will simply take their current business and course platform and provide a mobile user interface for it. By expanding the reach of Agora, Latin American teachers will be well equipped to teach their classes with innovation and effectiveness

tRNA/mRNA Mimicry by tmRNA and SmpB in Trans-Translation

Since accurate translation from mRNA to protein is critical to survival, cells have developed translational quality control systems. Bacterial ribosomes stalled on truncated mRNA are rescued by a system involving tmRNA and SmpB referred to as trans-translation. Here, we review current understanding of the mechanism of trans-translation. Based on results obtained by using directed hydroxyl radical probing, we propose a new type of molecular mimicry during trans-translation. Besides such chemical approaches, biochemical and cryo-EM studies have revealed the structural and functional aspects of multiple stages of trans-translation. These intensive works provide a basis for studying the dynamics of tmRNA/SmpB in the ribosome

Field-orientation dependence of quantum phase transitions in the S=1/2 triangular-lattice antiferromagnet Ba3_3CoSb2_2O9_9

Ba$_3$CoSb$_2$O$_9$ approximates the two-dimensional spin-1/2 triangular-lattice Heisenberg antiferromagnet. This compound displays magnetic-field-induced quantum phase transitions, including the 1/3-magnetization-plateau, but its magnetization processes for the magnetic field $H$ parallel and perpendicular to the $c$ axis are different due to the weak easy-plane anisotropy and the weak interlayer antiferromagnetic exchange interaction. To elucidate how the quantum phase transitions change between these two field directions, we measured the field-angle dependence of the magnetization process in Ba$_3$CoSb$_2$O$_9$ using pulsed high magnetic fields. We compared obtained magnetic field-field angle phase diagram with those obtained by the large-size cluster mean-field method combined with a scaling scheme and the semiclassical theory. We also found a narrow 1/3-magnetization plateau and a high-field transition with a small magnetization jump for $H\,{\parallel}\,c$, not observed in the previous studies.Comment: 8 pages, 7 figures, to appear in Phys. Rev.

Variable Stars in the Magellanic Clouds: Results from OGLE and SIRIUS

We have performed a cross-identification between OGLE-II data and single-epoch SIRIUS JHK survey data in the LMC and SMC. After eliminating obvious spurious variables, we determined the pulsation periods for 9,681 and 2,927 variables in the LMC and SMC, respectively. Based on these homogeneous data, we studied the pulsation properties and metallicity effects on period-K magnitude (PK) relations by comparing the variable stars in the LMC and SMC. The sample analyzed here is much larger, and we found the following new features: (1) variable red giants in the SMC form parallel sequences on the PK plane, just like those found by Wood (2000) in the LMC; (2) both of the sequences A and B of Wood (2000) have discontinuities, and they occur at the K-band luminosity of the TRGB; (3) the sequence B of Wood (2000) separates into three independent sequences B+- and C'; (4) comparison between the theoretical pulsation models (Wood et al. 1996) and observational data suggests that the variable red giants on sequences C and newly discovered C' are pulsating in the fundamental and first overtone mode, respectively; (5) the theory can not explain the pulsation mode of sequences A+- and B+-, and they are unlikely to be the sequences for the first and second overtone pulsators, as was previously suggested; (6) the zero points of PK relations of Cepheids in the metal deficient SMC are fainter than those of LMC ones by ~0.1 mag but those of SMC Miras are brighter than those of LMC ones by ~0.13 mag, which are probably due to metallicity effects.Comment: 9 pages, 10 figures, accepted for publication in MNRAS. High resolution version is available at: http://www.ioa.s.u-tokyo.ac.jp/~yita/scr/astro/papers/RefereedPaper/yitaMD250 .pd

Study on dioxygen reduction by mutational modifications of the hydrogen bond network leading from bulk water to the trinuclear copper center in bilirubin oxidase

The hydrogen bond network leading from bulk water to the trinuclear copper center in bilirubin oxidase is constructed with Glu463 and water molecules to transport protons for the four-electron reduction of dioxygen. Substitutions of Glu463 with Gln or Ala were attributed to virtually complete loss or significant reduction in enzymatic activities due to an inhibition of the proton transfer steps to dioxygen. The single turnover reaction of the Glu463Gln mutant afforded the highly magnetically interacted intermediate II (native intermediate) with a broad g = 1.96 electron paramagnetic resonance signal detectable at cryogenic temperatures. Reactions of the double mutants, Cys457Ser/Glu463Gln and Cys457Ser/Glu463Ala afforded the intermediate I (peroxide intermediate) because the type I copper center to donate the fourth electron to dioxygen was vacant in addition to the interference of proton transport due to the mutation at Glu463. The intermediate I gave no electron paramagnetic resonance signal, but the type II copper signal became detectable with the decay of the intermediate I. Structural and functional similarities between multicopper oxidases are discussed based on the present mutation at Glu463 in bilirubin oxidase. © 2014 Elsevier Inc. All rights reserved

The Infrared Counterpart of the X-Ray Nova XTE J1720-318

We report on the discovery of an infrared counterpart to the X-ray transient XTE J1720-318 on 2003 January 18, nine days after an X-ray outburst, and the infrared light curve during the first 130 days after the outburst. The infrared light curve shows a decline of about 1.2 mag from the peak magnitude of Ks about 15.3 over the observation period, and a secondary maximum, about 40 days after the outburst. Another small increase in the flux was also recorded about 20 days after the outburst. These increases were also detected in the X-ray light curve. The J H Ks colors are consistent with an X-ray irradiated accretion disk suffering an extinction of Av about 8, which is also inferred from its X-ray spectrum and the extinction map constructed from far-infrared dust emission of this line of sight. These J, H, and Ks observations demonstrate that useful data can be obtained even for such an object, which suffers heavy optical extinction, possibly located beyond the Galactic center.Comment: 5 pages, 2 figures, to appear in PAS