Global Visibility of Open Access Institutional Repositories of SAARC Countries: An Explorative Study

The concept of open access extends perceived advantages to its stakeholders, especially in the preservation of scholarly publications through digital repositories. Open Access (OA) improves collaboration among the authors with the support of global networks. There has been remarkable progress worldwide in creating institutional repositories to provide open access to resources. Open access institutional repositories (OAIR) provide a stable platform to showcase an individual\u27s intellectual works without a hitch. This study explores the visibility of open access institutional repositories of SAARC countries that are reflected in the Directory of Open Access Institutional Repository (DOAR). Collected data has been analyzed and represented in tabular and graphical formats to understand the variables\u27 relationship. The authors also assessed the contribution of SAARC countries concerning repository type, disciplines, languages covered, and software used for building them. The study\u27s finding revealed that out of 128 institutional repositories, the highest number of (14.06%) institutional repositories are registered in 2013 and 2019 and belong to the institutional category. DSpace is the software used for creating the majority of the repositories (60.94%), followed by E-Prints (25%). Three-fourths of the repositories are represented in the English language having its contents in journal articles. Among the SAARC countries, India contributes the highest number of institutional repositories (72.66%). The discipline-wise distribution of institutional repositories shows that the majority (18.40%) of the collection is represented under the category Science in general followed by multidisciplinary (15.74%) and technology in general 51 (12.35%) respectively as a concluding remark, authors elucidated the opportunities and threats associated with the development of OAIR to meet the educational requirements of the academic community

Research Performance of National Institute of Technology Rourkela: A Scientometric Analysis

This paper\u27s main objective is to perform a scientometric study on the National Institute of Technology, Rourkela, research publications, as reflected in the Scopus Database. The study evaluated the quantitative growth, author and Institute collaborations, using different scientometric dimensions. Appropriate keywords were used to cover the entire spectrum of research publications that yield 9233 results from the database. To make the analysis concise to get better outcomes, authors have limited the study period to the publications produced from 2000 to 2019. This study analyzed different aspects of research productivity, such as year-wise growth of publications, most preferred sources for the publications, authorship pattern, subject-wise distribution of papers, etc. Furthermore, the study also explored the international research collaboration patterns of the authors. The analysis identified 2018 as the most productive year with a publication of 1339 research papers and 102692 citations for all publications during the selected period, with an average of 11.12 citations per paper. The majority of the papers have double authorship patterns, and the degree of collaboration and collaborative co-efficient is apparent with a total of 0.97 and 0.61, respectively. The study further identified that Mahapatra, S. S was the most productive author with 295 articles and 5650 citations and the Core/shell nanoparticles: classes, properties, synthesis mechanisms, characterization, and applications by Ghosh Chaudhuri R Paria S. published in Chemical Reviews of 2012 is the most highly cited (2045) paper and \u27IOP Conference Series Material Science and Engineering\u27 is the topmost preferred source of publication. Scientometric studies are useful tools for measuring the scientific and technological progress that cannot be directly measured. Various scientometric indicators are used as analytical tools to perform such assessments

Research Productivity and Visualization of the All India Institute of Medical Sciences (AIIMS) Bhubaneswar during 2012-2019: A Scientometric Approach

The purpose of the present study is to evaluate the productivity of research at the Indian Institute of Medical Sciences (AIIMS), Bhubaneswar, in the first eight years (2012-2019) of its establishment. In this study, the authors used a number of Scientometric indices to assess research productivity. The results of the study showed that in the selected period of 2019, most research publications appear with an average growth rate of 46.43%. Most of the comments were written by five or more authors. In addition, R.R. Das is recognized as the most prolific author, and the Journal of Clinical and Diagnostic Research is one of the most popular sources of publications, with the largest number of publications with the help of scientists from AIIMS. The UK and AIIMS New Delhi are the countries and institutions that work best together. In addition, the study also found that the Indian Medical Research Council is the leading research institution with AIIMS Bhubaneswar. The title of Maiti R Metronomic Chemotherapy , published in the Journal of Pharmacology and Pharmacotherapeutics, received the most citations. this sentence is long and somewhat complicated. This study is useful for policymakers and stakeholders in medical institutions to improve their research prospects

Research Performance of National Institute of Technology Rourkela: A Scientometric Analysis

Scientometric studies are useful tools for measuring the scientific and technological progress that cannot be directly measured. Various scientometric indicators are used as analytical tools to perform such assessments. This study performed a scientometric analysis on the research publications of National Institute of Technology, Rourkela from 2000 to 2019 as reflected in the Scopus Database. The study analyzed different aspects of research productivity for 9233 publications and identified 2018 as the most productive year with a publication of 1339 research papers and 102692 citations for all publications with an average of 11.12 citations per paper. The majority of the papers have double authorship patterns, and the degree of collaboration and collaborative co-efficient is apparent with a total of 0.97 and 0.61, respectively. Study identified Mahapatra, S. S as the most productive author with 295 articles and 5650 citations and the "Core/shell nanoparticles: classes, properties, synthesis mechanisms, characterization, and applications" by Ghosh Chaudhuri R Paria S. published in Chemical Reviews of 2012 is the most highly cited (2045) paper and 'IOP Conference Series Material Science and Engineering' is the topmost preferred source of publication

Research Productivity and Visualization of the All India Institute of Medical Sciences (AIIMS) Bhubaneswar during 2012-2019: A Scientometric Approach

Scientometric analysis of research results enable individuals and institutions to understand their current status and improve their performance. The present study evaluate the productivity of research at the Indian Institute of Medical Sciences (AIIMS), Bhubaneswar using scientometric parameters. Study revealed that most research publications appeared with an average growth rate of 46.43%. and R.R. Das was the most prolific author. Journal of Clinical and Diagnostic Research was found to be the most popular source of publications and AIIMS Bhubaneswar the leading research institution. The title of Maiti R 'Metronomic Chemotherapy' published in the Journal of Pharmacology and Pharmacotherapeutics, received the highest citations. The findings of the study will be of use to the policy makers to improve research in the the area

CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells

The persistence of HIV reservoirs, including latently infected, resting CD4+ T cells, is the major obstacle to cure HIV infection. CD32a expression was recently reported to mark CD4+ T cells harboring a replication-competent HIV reservoir during antiretroviral therapy (ART) suppression. We aimed to determine whether CD32 expression marks HIV latently or transcriptionally active infected CD4+ T cells. Using peripheral blood and lymphoid tissue of ART-treated HIV+ or SIV+ subjects, we found that most of the circulating memory CD32+ CD4+ T cells expressed markers of activation, including CD69, HLA-DR, CD25, CD38, and Ki67, and bore a TH2 phenotype as defined by CXCR3, CCR4, and CCR6. CD32 expression did not selectively enrich for HIV- or SIV-infected CD4+ T cells in peripheral blood or lymphoid tissue; isolated CD32+ resting CD4+ T cells accounted for less than 3% of the total HIV DNA in CD4+ T cells. Cell-associated HIV DNA and RNA loads in CD4+ T cells positively correlated with the frequency of CD32+ CD69+ CD4+ T cells but not with CD32 expression on resting CD4+ T cells. Using RNA fluorescence in situ hybridization, CD32 coexpression with HIV RNA or p24 was detected after in vitro HIV infection (peripheral blood mononuclear cell and tissue) and in vivo within lymph node tissue from HIV-infected individuals. Together, these results indicate that CD32 is not a marker of resting CD4+ T cells or of enriched HIV DNA–positive cells after ART; rather, CD32 is predominately expressed on a subset of activated CD4+ T cells enriched for transcriptionally active HIV after long-term ART

Shape Transition in the Epitaxial Growth of Gold Silicide in Au Thin Films on Si(111)

Growth of epitaxial gold silicide islands on bromine-passivated Si(111) substrates has been studied by optical and electron microscopy, electron probe micro analysis and helium ion backscattering. The islands grow in the shape of equilateral triangles up to a critical size beyond which the symmetry of the structure is broken, resulting in a shape transition from triangle to trapezoid. The island edges are aligned along $Si[110]$ directions. We have observed elongated islands with aspect ratios as large as 8:1. These islands, instead of growing along three equivalent [110] directions on the Si(111) substrate, grow only along one preferential direction. This has been attributed to the vicinality of the substrate surface.Comment: revtex version 3.0, 11 pages 4 figures available on request from [email protected] - IP/BBSR/93-6

Medical students’ pattern of self-directed learning prior to and during the coronavirus disease 2019 pandemic period and its implications for Free Open Access Meducation within the United Kingdom

PURPOSE: Self-directed learning (SDL) has been increasingly emphasized within medical education. However, little is known about the SDL resources medical students use. This study aimed to identify patterns in medical students’ SDL behaviors, their SDL resource choices, factors motivating these choices, and the potential impact of the coronavirus disease 2019 (COVID-19) pandemic on these variables. Methods: An online cross-sectional survey comprising multiple-choice, ranked, and free-text response questions were disseminated to medical students across all 41 UK medical schools between April and July 2020. Independent study hours and sources of study materials prior to and during the COVID-19 pandemic were compared. Motivational factors guiding resource choices and awareness of Free Open Access Meducation were also investigated. Results: The target sample was 75 students per medical school across a total of 41 medical schools within the United Kingdom (3,075 total students), and 1,564 responses were analyzed. University-provided information comprised the most commonly used component of independent study time, but a minority of total independent study time. Independent study time increased as a result of the COVID-19 pandemic (P<0.001). All sub-cohorts except males reported a significant increase in the use of resources such as free websites and question banks (P<0.05) and paid websites (P<0.05) as a result of the pandemic. Accessibility was the most influential factor guiding resource choice (Friedman’s μrank=3.97, P<0.001). Conclusion: The use of learning resources independent of university provision is increasing. Educators must ensure equitable access to such materials while supporting students in making informed choices regarding their independent study behaviors

Understanding atrioventricular septal defect: Anatomoechocardiographic correlation

<p>Abstract</p> <p>Objective</p> <p>Correlate the anatomic features of atrioventricular septal defect with echocardiographic images.</p> <p>Materials and methods</p> <p>Sixty specimen hearts were studied by sequential segmental analysis. Echocardiograms were performed on 34 patients. Specimen hearts with findings equivalent to those of echocardiographic images were selected in order to establish an anatomo-echocardiographic correlation.</p> <p>Results</p> <p>Thirty-three specimen hearts were in situs solitus, 19 showed dextroisomerism, 6 were in situs inversus and 2 levoisomerism. Fifty-eight had a common atrioventricular valve and 2 had two atrioventricular valves. Rastelli types were determined in 21 hearts. Nine were type A, 2 intermediate between A and B, 1 mixed between A and B, 4 type B and 5 type C. Associated anomalies included pulmonary stenosis, pulmonary atresia atrial septal defect, patent ductus arteriosus and anomalous connection of pulmonary veins. Echocardiograms revealed dextroisomerism in 12 patients, situs solitus in 11, levoisomerism in 7 and situs inversus in 4. Thirty-one patients had common atrioventricular valves and three two atrioventricular valves. Rastelli types were established in all cases with common atrioventricular valves; 17 had type A canal defects, 10 type B, 3 intermediate between A and B, 1 mixed between A and B and 3 type C. Associated anomalies included regurgitation of the atrioventricular valve, pulmonary stenosis, anomalous connection of pulmonary veins, pulmonary hypertension and pulmonary atresia.</p> <p>Conclusion</p> <p>Anatomo-echocardiographic correlation demonstrated a high degree of diagnostic precision with echocardiography.</p

Srebf1a is a key regulator of transcriptional control for adipogenesis

Adipogenesis is regulated by a complex cascade of transcriptional factors, but little is known about the early events that regulate the adipogenic program. Here, we report the role of the srebf1a gene in the differentiation of fibroblastic 3T3-F442A cells. We found that expression of srebf1a depended on GSK3β activity and that GSK3β activity was necessary for C/EBPβ phosphorylation at Thr188. Knockdown of srebf1a inhibited the adipogenic program because it blocked the expression of genes encoding PPARγ2, C/EBPα, SREBP1c and even FABP4, demonstrating that SREBP1a activation is upstream of these three essential adipogenic transcription factors. Kinetic analysis during differentiation illustrated that the order of expression of adipogenic genes was the following: cebpb, srebf1a, pparg2, cebpa, srebp1c and fabp4. Our data suggest that srebf1a acts as an essential link between the GSK3β-C/EBPβ signaling axis and the beginning of the adipogenic transcriptional cascade