3,202 research outputs found
Action to AcquisitionâBoost Studentsâ English Learning Motivation with Filmmaking Project
In Taiwan, English is more a major subject matter for student to âstudyâ in school rather than a language for people to use in real life situations. Under the situation, students tend to have lower learning motivation when come to English classes, especially in higher academic settings, like universities. In order to boost studentsâ learning motivation as well as to encourage their productivity and creativity at the same time, a preliminary action research was conducted by two researchers collaboratively whereas one researcher is the instructor simultaneously. The major focus of the action research is concerning the application of âfilmmakingâ as a potentially effective tool to attract students into the classroom activities as well as the lesson content. For four semesters successively, a semester project has been assigned to 10 classes. By the end of each semester, reflections from students and the instructor were collected for refining purpose. From the studentsâ reflection and random interviews, an interesting comment appeared repeatedly: although the filmmaking project required them much effort and time, the results brought them the excessive fun and sense of accomplishment
Model Based WSN System Implementations Using PN-WSNA for Aquarium Environment Control in a House
AMPK- mediated formation of stress granules is required for dietary restriction- induced longevity in Caenorhabditis elegans
Stress granules (SGs) are nonmembranous organelles that are dynamically assembled and disassembled in response to various stressors. Under stressed conditions, polyadenylated mRNAs and translation factors are sequestrated in SGs to promote global repression of protein synthesis. It has been previously demonstrated that SG formation enhances cell survival and stress resistance. However, the physiological role of SGs in organismal aging and longevity regulation remains unclear. In this study, we used TIAR- 1::GFP and GTBP- 1::GFP as markers to monitor the formation of SGs in Caenorhabditis elegans. We found that, in addition to acute heat stress, SG formation could also be triggered by dietary changes, such as starvation and dietary restriction (DR). We found that HSF- 1 is required for the SG formation in response to acute heat shock and starvation but not DR, whereas the AMPK- eEF2K signaling is required for starvation and DR- induced SG formation but not heat shock. Moreover, our data suggest that this AMPK- eEF2K pathway- mediated SG formation is required for lifespan extension by DR, but dispensable for the longevity by reduced insulin/IGF- 1 signaling. Collectively, our findings unveil a novel role of SG formation in DR- induced longevity.In addition to heat stress, starvation and dietary restriction (DR) can activate stress granule (SG) formation in Caenorhabditis elegans. HSF- 1 and AMPK are two key regulators for the SG formations. HSF- 1 is required for the SG formation in response to acute heat shock and starvation but not DR, whereas the AMPK- eEF2K pathway is required for starvation and DR- induced SG formation but not heat shock. Furthermore, AMPK- mediated SG formation contributes to DR- induced longevity.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/155936/1/acel13157-sup-0008-Figurelegends.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/155936/2/acel13157-sup-0001-FigS1.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/155936/3/acel13157-sup-0006-TableS1.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/155936/4/acel13157-sup-0007-TableS2.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/155936/5/acel13157-sup-0005-FigS5.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/155936/6/acel13157-sup-0003-FigS3.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/155936/7/acel13157.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/155936/8/acel13157-sup-0002-FigS2.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/155936/9/acel13157-sup-0004-FigS4.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/155936/10/acel13157_am.pd
Pelvic Osteotomies for Developmental Dysplasia of the Hip
Treatment of developmental dysplasia of the hip (DDH) is based on concentric reducibility of the femoral head, patient age and the status of triradiate cartilage. Patients in walking age are indicated for pelvic osteotomy to correct the dysplastic acetabulum. Salter innominate osteotomy and Pemberton osteotomy are the most widely used procedures to treat the developmental dysplasia of the hip in early childhood. Although short-term results of the pelvic osteotomies are reported well, some long-term sequalae such as coxa valga caused by Kalamchi type II osteonecrosis of the femoral head, leg length discrepancy and impingement of hip may occur
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