Effectiveness of Simeprevir Plus Sofosbuvir, With or Without Ribavirin, in Real-World Patients With HCV Genotype 1 Infection

The interferon-free regimen of simeprevir plus sofosbuvir was recommended by professional guidelines for certain patients with hepatitis C virus (HCV) genotype 1 infection based on the findings of a phase 2 trial. We aimed to evaluate the safety and efficacy of this regimen in clinical practice settings in North America

Muir String Quartet

This is the concert program of the Muir String Quartet performance on Monday, February 24, 1997 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue. Works performed were Quartet in F major, Op. 18. No. 1 by Ludwig van Beethoven, Quartet NO. 3 Sz. 85 by Bela Bartok, and Piano Quintet in F minor, Op. 34 by Johannes Brahms. Digitization for Boston University Concert Programs was supported by the Boston University Humanities Library Endowed Fund

Muir Quartet, November 9, 1995

This is the concert program of the Muir Quartet performance on Thursday, November 9, 1995 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue, Boston, Massachusetts. Works performed were String Quartet in C major, K. 465 "Dissonant" by Wolfgang Amadeus Mozart, String Quartet No. 1 "Kreutzer Sonata" by Leos Janacek, and Piano Quintet in C minor, Op. 115 by Gabriel Fauré. Digitization for Boston University Concert Programs was supported by the Boston University Humanities Library Endowed Fund

Muir String Quartet

This is the concert program of the Muir String Quartet performance on Sunday, September 29, 1996 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue. Works performed were Quartet Nr.1, Op.7, Sz.40 by Bela Bartok, and Quartet in A minor, Op.29, D 804, "Rosamude" by Franz Schubert. Digitization for Boston University Concert Programs was supported by the Boston University Humanities Library Endowed Fund

MP 2005-07

This article is reprinted from Agroborealis 37.1

The search for an identification of amino acids, nucleobases and nucleosides in samples returned from Mars

The Mars Sample Return mission will provide us with a unique source of material from our solar system; material which could advance our knowledge of the processes of chemical evolution. As has been pointed out, Mars geological investigations based on the Viking datasets have shown that primordial Mars was in many biologically important ways similar to the primordial Earth; the presence of surface liquid water, moderate surface temperatures, and atmosphere of carbon dioxide and nitrogen, and high geothermal heat flow. Indeed, it would seem that conditions on Earth and Mars were fundamentally similar during the first one billion years or so. As has been pointed out, Mars may well contain the best preserved record of the events that transpired on the early planets. Examination of that early record will involve searching for many things, from microfossils to isotopic abundance data. We propose an investigation of the returned Mars samples for biologically important organic compounds, with emphases on amino acids, the purine and pyrimidine bases, and nucleosides

Polyelectrolyte-modified cowpea mosaic virus for the synthesis of gold nanoparticles

Polyelectrolyte surface-modified cowpea mosaic virus (CPMV) can be used for the templated synthesis of narrowly dispersed gold nanoparticles. Cationic polyelectrolyte, poly(allylamine) hydrochloride, is electrostatically bound to the external surface of the virus capsid. The polyelectrolyte-coated CPMV promotes adsorption of aqueous gold hydroxide anionic species, prepared from gold(III) chloride and potassium carbonate, that are easily reduced to form CPMV-templated gold nanoparticles. The process is simple and environmentally benign using only water as solvent at ambient temperature