9,070 research outputs found

    Strategy Selection for Product Service Systems Using Case-based Reasoning

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    A product service system integrates products and services in order to lower environmental impact. It can achieve good eco-efficiency and has received increase in the last decade. This study focuses on strategy selection for product service system design. Case-based reasoning is utilized to provide suggestions for finding an appropriate strategy. To build a case database, successful PSS cases from the literature and websites were collected and formulated. Twelve indices under three categories were analyzed and selected to describe cases. A lot of successful PSS cases and their information were collected. Forty seven cases were used in this study because of the completeness of information. The analytic hierarchic process is used to find the relative weights of the factors that relate to the selection of customers. These weights are used in calculating the similarity in the case-based reasoning process. The successful strategy of the most similar case is extracted and recommended for PSS strategy determination. More than 90% of tested cases obtained an appropriate strategy from the most similar case. Finally, two new products are introduced to find the best strategy for product service system design and development using the proposed case-based reasoning system

    Diagnosis and surgical treatment of multiple endocrine neoplasia type 2A

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    BACKGROUND: This study aims to introduce the diagnosis and surgical treatment of the rare disease multiple endocrine neoplasia type 2A (MEN 2A). METHODS: Thirteen cases of MEN 2A were diagnosed as medullary thyroid carcinoma (MTC) and pheochromocytoma by biochemical tests and imaging examination. They were treated by bilateral adrenal tumor excision or laparoscopic surgery. RESULTS: Nine patients were treated by bilateral adrenal tumor excision and the remaining four were treated by laparoscopic surgery for pheochromocytoma. Ten patients were treated by total thyroidectomy and bilateral lymph nodes dissection and the remaining three were treated by unilateral thyroidectomy for MTC. Up to now, three patients have died of MTC distant metastasis. CONCLUSIONS: We confirmed that MEN 2A can be diagnosed by biochemical tests and imaging examination when genetic testing is not available. Surgical excision is the predominant way to treat MEN 2A; pheochromocytoma should be excised at first when pheochromocytoma and MTC occur simultaneously

    Mechanics of Tunable Helices and Geometric Frustration in Biomimetic Seashells

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    Helical structures are ubiquitous in nature and engineering, ranging from DNA molecules to plant tendrils, from sea snail shells to nanoribbons. While the helical shapes in natural and engineered systems often exhibit nearly uniform radius and pitch, helical shell structures with changing radius and pitch, such as seashells and some plant tendrils, adds to the variety of this family of aesthetic beauty. Here we develop a comprehensive theoretical framework for tunable helical morphologies, and report the first biomimetic seashell-like structure resulting from mechanics of geometric frustration. In previous studies, the total potential energy is everywhere minimized when the system achieves equilibrium. In this work, however, the local energy minimization cannot be realized because of the geometric incompatibility, and hence the whole system deforms into a shape with a global energy minimum whereby the energy in each segment may not necessarily be locally optimized. This novel approach can be applied to develop materials and devices of tunable geometries with a range of applications in nano/biotechnology

    Experimental Observation of Topological Superconductivity and Majorana Zero Modes on beta-Bi2Pd Thin Films

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    Using a cryogenic scanning tunneling microscopy, we report the observation of topologically nontrivial superconductivity on a single material of \beta-Bi2Pd films grown by molecular beam epitaxy. The superconducting gap associated with spinless odd-parity pairing opens on the surface and appears much larger than the bulk one due to the Dirac-fermion enhanced parity mixing of surface pair potential. Majorana zero modes (MZMs), supported by such superconducting states, are identified at magnetic vortices. The superconductivity and MZMs exhibit resistance to nonmagnetic defects, characteristic of time-reversal-invariant topological superconductors. Our results demonstrate a simple platform to generate, manipulate and braid MZMs for quantum computation.Comment: 9 pages, 8 figure

    Segatron: Segment-Aware Transformer for Language Modeling and Understanding

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    Transformers are powerful for sequence modeling. Nearly all state-of-the-art language models and pre-trained language models are based on the Transformer architecture. However, it distinguishes sequential tokens only with the token position index. We hypothesize that better contextual representations can be generated from the Transformer with richer positional information. To verify this, we propose a segment-aware Transformer (Segatron), by replacing the original token position encoding with a combined position encoding of paragraph, sentence, and token. We first introduce the segment-aware mechanism to Transformer-XL, which is a popular Transformer-based language model with memory extension and relative position encoding. We find that our method can further improve the Transformer-XL base model and large model, achieving 17.1 perplexity on the WikiText-103 dataset. We further investigate the pre-training masked language modeling task with Segatron. Experimental results show that BERT pre-trained with Segatron (SegaBERT) can outperform BERT with vanilla Transformer on various NLP tasks, and outperforms RoBERTa on zero-shot sentence representation learning.Comment: Accepted by AAAI 202
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