Knowledge and awareness among female patients attending cardiac outpatient department in a super speciality hospital

Background: Cardiovascular disease is the leading cause of mortality not only in males but also in females and knowledge about the disease is poor among them. Objective of the study was to assess the knowledge and awareness among female cardiac patients.Methods: This cross-sectional study was conducted in outpatient department of cardiology in a super specialty hospital of government medical college Jammu, Jammu and Kashmir, for a period of three month from 1st March to 31st May 2017. Female patients were given a questionnaire regarding socio demographic profile, knowledge and awareness were recorded and analyzed in percentage.Results: There were 216 female patients, out of which 56.9% were in age group of 41-60 years, 86.1% were housewives, 87.5% were married, 54.1% having education up to 10th standard and maximum were living in joint family and 52.7% having monthly family income above 20,000. 44.4% were suffering from hypertension. Maximum females 59.7% consider themselves as bulky, 83% have changed their eating habits, 66.6% have started work out after the onset of disease, 61%-62% were having awareness about the cardiac symptoms and 97.2% were following allopathic drug therapy.Conclusions: Overall knowledge and awareness about disease and risk factors among these females was good as these patients were already diagnosed patients and were coming for follow up. There is need of educational programme by involving primary health care workers and utilization of CVD guidelines as a better preventive strategy

AWARENESS, STRESS, ANXIETY, AND DEPRESSION AMONG HYPERTENSIVE PATIENTS ATTENDING CARDIAC OUTPATIENT DEPARTMENT IN A SUPER SPECIALTY HOSPITAL

Objective: Hypertension is a major risk factor for cardiovascular disease and its association with negative emotions may increase their risk forthe development of mental health disorders. The main objective of the study was to assess the awareness, stress, anxiety, and depression amonghypertensive patients attending cardiac outpatient department (OPD).Methods: This study was conducted in cardiac OPD of Super Speciality Hospital associated with Government Medical College, Jammu, for a period of1-month commencing from 1st October to 31st October 2015. Hypertensive patients were given a questionnaire regarding socio-demographic profile,risk factors, and awareness for high blood pressure, and prevalence of stress, anxiety, and depression was assessed using a structured validatedquestionnaire DASS-21 [depression, anxiety, and stress scale-21].Results: It was observed that most (72.5%) of the patients were aware of symptoms and its complications and regarding psychological symptomsmild to severe depressive symptoms were present in 10%, anxiety in 70%, and stress in 10% of patients.Conclusion: There is need of psychiatric evaluation and counseling in these patients and support services to be made available to these patients.Keywords: Hypertension, Awareness, Stress, Anxiety, Depression, Depression; anxiety and stress scale-21

Assessment of Knowledge, Attitude and Practice related to Tuberculosis among Rural and Urban Community of North India

Tuberculosis is known as one of the long-standing and dominating health problems affecting people and the extent further escalates in a developing country like India. A pre-evaluated feedback structured questionnaire was validated and adopted to get their quantitative data from 424 respondents. In the present study urban respondents (60.8%) gave affirmative responses regarding awareness of TB, especially with mobile media as their major source of information, followed by information from healthcare workers. Rural respondents were less expressed and deficient on knowledge of TB transmission and preventive methods. Prevention practices toward TB are claimed to be high in urban population because 79.48% believed that early diagnosis, prompt treatment and avoiding poor hygiene and crowded environment are effective strategies to cease the transmission of TB. Effective preventive and informative strategies should be employed in rural border areas to make up for the knowledge gap found among rural and urban populations in this study

How the global airline industry behaved to restrictions on air travel to India? An event study analysis

We examine the impact of the recent restrictions/bans imposed by several nations on air travel to India in the light of the increasing number of infections amid the second wave of covid-19. We employ the standard event study method on a sample of 34 airline stocks across seven nations to find that the recent restrictions/ bans on air travel significantly impact the global airline industry, although the country-specific impacts are not similar. We find that the post-event reaction in all nations has been different from those evidenced during the global pandemic declaration. We are the first to examine these impacts during the current wave of the pandemic. It contributes to the literature on the effects of the pandemic on the global airline industry. Further, it also provides practical explanations to the investors on how the airline stocks react to the persistence of the pandemi

Direct Analysis in Real Time by Mass Spectrometric Technique for Determining the Variation in Metabolite Profiles of Cinnamomum tamala Nees and Eberm Genotypes

Cinnamomum tamala Nees & Eberm. is an important traditional medicinal plant, mentioned in various ancient literatures such as Ayurveda. Several of its medicinal properties have recently been proved. To characterize diversity in terms of metabolite profiles of Cinnamomum tamala Nees and Eberm genotypes, a newly emerging mass spectral ionization technique direct time in real time (DART) is very helpful. The DART ion source has been used to analyze an extremely wide range of phytochemicals present in leaves of Cinnamomum tamala. Ten genotypes were assessed for the presence of different phytochemicals. Phytochemical analysis showed the presence of mainly terpenes and phenols. These constituents vary in the different genotypes of Cinnamomum tamala. Principal component analysis has also been employed to analyze the DART data of these Cinnamomum genotypes. The result shows that the genotype of Cinnamomum tamala could be differentiated using DART MS data. The active components present in Cinnamomum tamala may be contributing significantly to high amount of antioxidant property of leaves and, in turn, conditional effects for diabetic patients

Paternal imprinting of the SLC22A1LS gene located in the human chromosome segment 11p15.5

BACKGROUND: Genomic imprinting is an epigenetic chromosomal modification in the gametes or zygotes that results in a non-random monoallelic expression of specific autosomal genes depending upon their parent of origin. Approximately 44 human genes have been reported to be imprinted. A majority of them are clustered, including some on chromosome segment 11p15.5. We report here the imprinting status of the SLC22A1LS gene from the human chromosome segment 11p15.5 RESULTS: In order to test for allele specific expression patterns, PCR primer sets from the SLC22A1LS gene were used to look for heterozygosity in DNA samples from 17 spontaneous abortuses using PCR-SSCP and DNA sequence analyses. cDNA samples from different tissues of spontaneous abortuses showing heterozygosity were subjected to PCR-SSCP analysis to determine the allele specific expression pattern. PCR-SSCP analysis revealed heterozygosity in two of the 17 abortuses examined. DNA sequence analysis showed that the heterozygosity is caused by a G>A change at nucleotide position 473 (c.473G>A) in exon 4 of the SLC22A1LS gene. PCR-SSCP analysis suggested that this gene is paternally imprinted in five fetal tissues examined. CONCLUSIONS: This study reports the imprinting status of the SLC22A1LS gene for the first time. The results suggest imprinting of the paternal allele of this gene in five fetal tissues: brain, liver, placenta, kidneys and lungs

Technique for crossing and advancing multiple generations for mungbean (Vigna radiata L.)

Mungbean (Vigna radiata L.) Wilczek (2n=2×=22) is an important grain legume cultivated in South-east Asia, Africa, South America and Australia (Shanmugasundram 2007). About 90% of mungbean production occurs in South Asia, where India is the largest producer. It is consumed in various forms like, seed as a good source of easily digested dietary proteins and amino acids. Young pods and sprouts are consumed as vegetable for vitamin and mineral supplement (Engel 1977). Its plant parts are used as fodder for animal and green manure to improve soil health in rice-wheat cropping system (Sharma et al. 1995; Bhuiyan et al. 2009; Yaqub et al. 2010). It is grown as a sole crop as well as a major component in various cropping systems owing to its ability to fix atmospheric nitrogen, rapid growth, and early maturity. Mungbean being a photo insensitive crop is grown in a wide range of climatic variations (Tiwari and Ramanujam 1976) and ideal for catch, inter and relay cropping in many countries (Ali et al. 2000). Because of wide adoptability at various temperature ranges, this crop is likely to be most suitable under currently rising global temperatur

Haemoglobinopathies- thalassaemias and abnormal haemoglobins in Eastern Uttar Pradesh and adjoining districts of neighbouring states

The haemoglobinopathies- thalassaemias and abnormal haemoglobins- constitute a major burden of genetic diseases in India. Our study, based on index cases from 120 families detected between May 1999 and May 2003, highlights the ethnic distribution of haemoglobinopathies in regions in and around Varanasi comprising 8-10 districts of eastern Uttar Pradesh and adjoining districts of Bihar, Jharkhand, Chhattisgarh and Madhya Pradesh. Homozygous and heterozygous β-thalassaemia was the most common (66.9%), with thalassaemic haemoglobinopathies HbE-β-thalassaemia (15.9%) and HbS-β-thalasseamia (7.8%) contributing to almost a quarter of the cases. Along with HbSS disease (4.3%), the results indicate a confluence of β-thalassaemia, HbS and HbE in this region. IVS1-5 nt was the most common mutation in the few carriers analysed for mutation detection. The significance of the study lies in the demonstration of wide prevalence of β-thalassaemia across all castes and communities of this region, with migrant population groups of Sindhis and Punjabis comprising only 5.8% of the index cases. Also, HbE seems to have a much higher presence in this region than so far believed and HbS has a significant presence in general castes as well