Coronary angiographic abnormalities in patients of diabetes mellitus and metabolic syndrome

Background: Diabetes mellitus and Metabolic syndrome, both are established risk factors for CAD. In our study, we tried to compare the effects of these two diseases individually as well as their combined effect.Methods: we performed an Observational, cross-sectional, hospital-based, single center study on 240 patients presenting at our hospital with chest pain. we assessed the severity of CAD with Syntax score and divided the study population into three groups with SS of =33.Results: statistically significant difference was found in each of the first three groups of combined MS plus DM, only MS without DM, only DM without MS when compared with the fourth group of nondiabetics nonmetabolic syndrome patients. Strongest difference was found between patients with combined diabetes and metabolic syndrome with those who had none of these (<0.001). Thus, complexity of CAD is much severe in patients who have diabetes and/or metabolic syndrome.Conclusions: Patients having diabetes mellitus and/or metabolic syndrome are found to have more severe form of coronary artery disease than those who don’t have either of these. However, presence of both diabetes and metabolic syndrome has not been found to impose any significant additional risk than their isolated presence

A study to find out relationship in between ankle brachial index and severity of coronary artery disease as assessed by SYNTAX score

Background: Peripheral arterial disease and coronary artery disease shares common risk factors for Etiopathogenesis. Present study is designed to find out relationship between ankle brachial index (ABI) and SYNTAX Score.Methods: Total 100 consecutive patients of stable coronary artery disease in whom angiography was indicated were taken for the study. ABI was measured by using 8 MHz vascular Doppler before coronary angiography and SYNTAX SCORE was calculated by using online SYNTAX score calculator. Statistical analysis was done by SPSS 21 software.Results: There was significant correlation in between low ABI and presence of triple vessel disease in comparison to presence of single or double vessel disease for which it was not significant. (P&lt;0.001) There was significant correlation in between high SYNTAX score &gt;32 and low ABI group (P=0.005) although this relationship was not seen in case of low and intermediate SYNTAX Score and low ABI.Conclusions: presence of low ABI signifies presence of high SYNTAX Score and presence of triple vessel disease