29 research outputs found
Development of engineering solutions for air drilling at Dulisminsk oilfield, Irkutsk oblast
The article presents the analysis of disastrous mud loss achieved during casing at Dulisminsk oil and gas condensate field (DOGCF) and comparative evaluation of geological structure of DOGCF and Naryksko-Ostashkinsk area of Kemerovo oblast, where the same problem was solved successfully. On the basis of the analysis, an engineering solution is proposed to prevent mud loss in the conditions of DOGCF
Magnetic gap of fe-doped BiSbTe<sub>2</sub>Se bulk single crystals detected by tunneling spectroscopy and gate-controlled transports
Topological insulators with broken time-reversal symmetry and the Fermi level within the magnetic gap at the Dirac cone provides exotic topological magneto-electronic phenomena. Here, we introduce an improved magnetically doped topological insulator, Fe-doped BiSbTe2Se (Fe-BSTS) bulk single crystal, with an ideal Fermi level. Scanning tunneling microscopy and spectroscopy (STM/STS) measurements revealed that the surface state possesses a Dirac cone with the Dirac point just below the Fermi level by 12 meV. The normalized dI/dV spectra suggest a gap opening with Δmag ~55 meV, resulting in the Fermi level within the opened gap. Ionic-liquid gated-transport measurements also support the Dirac point just below the Fermi level and the presence of the magnetic gap. The chemical potential of the surface state can be fully tuned by ionic-liquid gating, and thus the Fe-doped BSTS provides an ideal platform to investigate exotic quantum topological phenomena.</p
High-mobility compensated semimetals, orbital magnetization, and umklapp scattering in bilayer graphene moire superlattices
Twist-controlled moire superlattices (MS) have emerged as a versatile platform in which to realize artificial systems with complex electronic spectra. Bernal-stacked bilayer graphene (BLG) and hexagonal boron nitride (hBN) form an interesting example of the MS that has recently featured a set of unexpected behaviors, such as unconventional ferroelectricity and electronic ratchet effect. Yet, the understanding of the BLG/hBN MS electronic properties has, at present, remained fairly limited. Here we develop a multi-messenger approach that combines standard magnetotransport techniques with low-energy sub-THz excitation to get insights into the properties of this MS. We show that BLG/hBN lattice alignment results in the emergence of compensated semimetals at some integer fillings of the moire bands separated by van Hove singularities where Lifshitz transition occurs. A particularly pronounced semimetal develops when 8 electrons reside in the moire unit cell, where coexisting high-mobility electron and hole systems feature a strong magnetoresistance reaching 2350 % already at B=0.25 T. Next, by measuring the THz-driven Nernst effect in remote bands, we observe valley splitting, pointing to an orbital magnetization characterized by a strongly enhanced effective g-factor of 340. Last, using THz photoresistance measurements, we show that the high-temperature conductivity of the BLG/hBN MS is limited by electron-electron umklapp processes. Our multi-facet analysis introduces THz-driven magnetotransport as a convenient tool to probe the band structure and interaction effects in vdW materials and provides a comprehension of the BLG/hBN MS
Simulations of M87 and Sgr A* imaging with the Millimetron Space Observatory on near-Earth orbits
High resolution imaging of supermassive black holes shadows is a direct way
to verify the theory of general relativity at extreme gravity conditions. Very
Long Baseline Interferometry (VLBI) observations at millimeter/sub-millimeter
wavelengths can provide such angular resolution for supermassive black holes,
located in Sgr A* and M87. Recent VLBI observations of M87 with the Event
Horizon Telescope (EHT) has shown such capabilities. The maximum obtainable
spatial resolution of EHT is limited by Earth diameter and atmospheric phase
variations. In order to improve the image resolution longer baselines are
required. Radioastron space mission has successfully demonstrated the
capabilities of Space-Earth VLBI with baselines much larger than Earth
diameter. Millimetron is a next space mission of the Russian Space Agency that
will operate at millimeter wavelengths. Nominal orbit of the observatory will
be located around Lagrangian L2 point of the Sun-Earth system. In order to
optimize the VLBI mode, we consider a possible second stage of the mission that
could use near-Earth high elliptical orbit (HEO). In this contribution a set of
near-Earth orbits is used for the synthetic space-ground VLBI observations of
Sgr A* and M87 in joint Millimetron and EHT configuration. General-relativistic
magnetohydrodynamic models (GRMHD) for black hole environment of Sgr A* and M87
are used for static and dynamic imaging simulations at 230 GHz. A comparison
preformed between ground and space-ground baselines demonstrates that joint
observations with Millimetron and EHT significantly improve the image
resolution and allow the EHT+Millimetron to obtain snapshot images of Sgr A*
probing dynamics at fast timescales.Comment: 12 pages, 6 figure
Immunosuppressive potential of human amnion epithelial cells in the treatment of experimental autoimmune encephalomyelitis
BACKGROUND: Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system (CNS). In recent years, it has been found that cells such as human amnion epithelial cells (hAECs) have the ability to modulate immune responses in vitro and in vivo and can differentiate into multiple cell lineages. Accordingly, we investigated the immunoregulatory effects of hAECs as a potential therapy in an MS-like disease, EAE (experimental autoimmune encephalomyelitis), in mice. METHODS: Using flow cytometry, the phenotypic profile of hAECs from different donors was assessed. The immunomodulatory properties of hAECs were examined in vitro using antigen-specific and one-way mixed lymphocyte proliferation assays. The therapeutic efficacy of hAECs was examined using a relapsing-remitting model of EAE in NOD/Lt mice. T cell responsiveness, cytokine secretion, T regulatory, and T helper cell phenotype were determined in the peripheral lymphoid organs and CNS of these animals. RESULTS: In vitro, hAECs suppressed both specific and non-specific T cell proliferation, decreased pro-inflammatory cytokine production, and inhibited the activation of stimulated T cells. Furthermore, T cells retained their naïve phenotype when co-cultured with hAECs. In vivo studies revealed that hAECs not only suppressed the development of EAE but also prevented disease relapse in these mice. T cell responses and production of the pro-inflammatory cytokine interleukin (IL)-17A were reduced in hAEC-treated mice, and this was coupled with a significant increase in the number of peripheral T regulatory cells and naïve CD4+ T cells. Furthermore, increased proportions of Th2 cells in the peripheral lymphoid organs and within the CNS were observed. CONCLUSION: The therapeutic effect of hAECs is in part mediated by inducing an anti-inflammatory response within the CNS, demonstrating that hAECs hold promise for the treatment of autoimmune diseases like MS
Immunosuppressive potential of human amnion epithelial cells in the treatment of experimental autoimmune encephalomyelitis
Forward-angle values of polarization-transfer (pt) coefficients for the 16O (p,p) 16O (4-, T=1) and 28 Si (p,p) 28Si(6-, T=1) reactions
Section II. Experimental Investigations of Nuclear Reactions Mechanism