Protokół terapeutyczny w dokumentowaniu procesu napromieniania pacjentów w zakładzie radioterapii

SummaryA decision to start radiotherapy should be based on at least two documents:1.Written standards of obligatory clinical procedures which are in fact radiotherapeutic schemes.2.Therapeutic protocols describing all mandatory procedures performed to ensure a safe and proper treatment of the patient.The range of activities described in the therapeutic protocol is very wide.It includes all initial procedures implemented in the simulation room, the CT scanner, in the treatment planning system and the mould- room, and it describes the verification process of the treatment plan, mandatory to start radiotherapy.The therapeutic protocol describes in details what and how should be checked by an internal control system and it qualifies the demands required to sum up the treatment and its’ accordance with the planned radiotherapy scheme.All the activities performed are recorded in a QA protocol, which is an integral part of the therapeutic protocol.In this paper we present the therapeutic protocol in force in the Regional Oncological Hospital in Szczecin and the QA and in-vivo protocols, which assure safe radiotherapy of the patient

A radiotherapy protocol to document the process of irradiation of patients at the radiotherapy department

A decision to start radiotherapy should be based on at least two documents:1.Written standards of obligatory clinical procedures which are in fact radiotherapeutic schemes.2.Therapeutic protocols describing all mandatory procedures performed to ensure a safe and proper treatment of the patient.The range of activities described in the therapeutic protocol is very wide.It includes all initial procedures implemented in the simulation room, the CT scanner, in the treatment planning system and the mould- room, and it describes the verification process of the treatment plan, mandatory to start radiotherapy.The therapeutic protocol describes in details what and how should be checked by an internal control system and it qualifies the demands required to sum up the treatment and its’ accordance with the planned radiotherapy scheme.All the activities performed are recorded in a QA protocol, which is an integral part of the therapeutic protocol.In this paper we present the therapeutic protocol in force in the Regional Oncological Hospital in Szczecin and the QA and in-vivo protocols, which assure safe radiotherapy of the patient

Small cell carcinoma with neuroendocrine differentiation of subglottic larynx- a case report

Small cell cancer (SCC) is a neuroendocrine neoplasm, which is most frequently found in the lungs. Extrapulmonary location of SCC is rare and may involve 2.5-5% of SCCs. We present a case of a 31-year-old male patient with an extremely uncommon subglottic SCC. The patient was qualified for a radical sequential chemoradiotherapy. After treatment, patient’s condition suggested complete remission. Recurrence was detected one year later, and the disease rapidly progressed, despite a second line chemotherapy. The patient died 29 months after initial diagnosis. This case aims to raise awareness on the aggressive laryngeal SCC and its good response to first line chemotherapy composed of cisplatin and etoposide, followed by radiotherapy

Zastosowanie wewnątrznosowej operacji zatok w leczeniu paliatywnym raka zatoki szczękowej – doniesienie wstępne

The authors present a case of 64 years old woman treated with palliative radiotherapy due to maxillary sinus cancer – non-operative stage. The cancer-relative pain couldn’t be released after radiotherapy and with pain killers. She used NSAIDs and opioid drugs. Before chemiotherapy she was undertaken intranasal sinus operation as a palliative operation. Maxillary sinus was opened. The pain after operation diminished significantly. She died 2 and a half months later, during chemiotherapy, but free of pain

Przyśpieszona pooperacyjna radioterapia u chorych na zaawansowanego raka krtani

Aim: The aim of study was test effi cacy of accelerated postoperative radiotherapy – concomitant boost in patients with advanced larynx cancer. Methods and Materials: The prospective study included 112 patients with advanced larynx cancer after radical surgical treatment. Patients had postoperative radiation therapy, conventional (C) or accelerated (CB). Results: The 3-year overall survival in CB was 59%, in C – 58% (p=0,2), 3-year locoregional control in CB – 83%, in C – 75% (p=0.01), the 3-year disease free survival was in CB – 72%, C – 66% (p=0.1). Conclusion: Concomitant boost postoperative radition therapy did not improove overall survival, loco-regional control, disease free survival. Patients with close surgical margins, longer interval between surgery and radiation, high level of hemoglobin, T4 had benefi t from accelerated radiotherapy

Outcome of a multimodal therapy of a recurrent adenocarcinoma arising from Caesarean section scar endometriosis—A case report

BackgroundEndometriosis occurring in surgical scars is a well-described entity. Malignant transformation of endometriosis is a rare event, with most cases belonging to adenocarcinoma. The initial surgical treatment is a method of choice. Due to lack of therapeutic recommendations, adjuvant therapy and recurrence management are a great challenge for oncologists.AimThe aim of this paper was to present a long-term survival as the outcome of multimodal therapy in the patient with recurrent adenocarcinoma arising from Caesarean section scar endometriosis.CaseWe present the case of a woman with recurrent adenocarcinoma arising from Caesarean section scar endometriosis. The disease was first diagnosed in September 1997 at age 43. The patient underwent abdominal hysterectomy with tumour excision. Due to a local recurrence after 4 years, tumour excision with abdominal wall repair using a plastic mesh, regional lymphadenectomy, bilateral salpingo-ovariectomy and adjuvant radiotherapy for the pelvic region with local boost were performed; in addition hormontherapy with medroxyprogesterone was started. Because of a recurrent pelvic tumour, chemotherapy, further local palliative radiotherapy and brachytherapy were administered. Subsequently distant metastases in bilateral axillary lymph nodes were diagnosed and palliative radiotherapy was performed. The patient died of morbus neoplasmaticus generalisatus in September 2008. The follow-up period had been 132 months.ConclusionThis paper is, to our knowledge, the only report in literature that presents a long-term survival as the outcome of multimodal therapy in the patient with this rare diagnosis. Further reports of new cases can help establish optimal treatment guidelines

Analiza czynników rokowniczych u chorych z miejscowo zaawansowanym rakiem krtani

Purpose. Results of treatment of locally advanced larynx cancer T3-4No-4 are unsatisfied. The aim of study is analysis of risk factors. Methods and Materials. 112 patients with larynx cancer after radical surgical treatment had postoperative radiotherapy (conventional or accelarated). Results. The 3-year overall survival (OS) was 58%. Margin status and numer of risk factors had impast on OS. The 3-year locoregional control (LRC) was 80%. Number of risk factors, level of hemoglobin, overall treatment time and dose were significantly associated with LRC. Incidence of distant metastases was asssociated with G3 suamous cell carcinoma and index of nalignancy H. Glanz

A rare mutation in a rare tumor-SMARCB1-deficient malignant glomus tumor

status: publishe