How Economic Situation Effect on Career Anchors of IT Personnel?

The paper examines how ITP (IT personnel) turnover intention is influenced by career satisfaction, and perceived job alternatives. What considerations lead an IT professional to switch jobs when they are currently satisfied; i.e. when their career anchors are satisfied

KINEMATICAL ANALYSIS OF TWO DIFFERENT FOREHAND BADMINTON DROP SHOTS TECHNIQUES

The purpose of this study was to compare the kinematics variables between badminton forehand regular and reverse slice drop shots. The participants were eight elite male players. Eight Vicon Motion T20s System cameras (300Hz) were used to record the 3D kinematic data, which were computed by Visual 3D software. All the variables were tested by Wilcoxon rank analysis of variance nonparametric statistical test with the significant level at a = .05. The results showed that there was significant difference between the two forehand drop shots in the racket pan angle. The strategy of two drop shots seems different. That might because the reverse slice drop was with greater shoulder abduction movement than the regular drop shot. The players performed reverse slice drop shot might because that the abduction movement was similar with the smash

USCID fourth international conference

Presented at the Role of irrigation and drainage in a sustainable future: USCID fourth international conference on irrigation and drainage on October 3-6, 2007 in Sacramento, California.In addition to increasingly frequent water shortage problems, agricultural water sector is also challenged by environmental issues. The objective of this article is to summarize, as well as propose sustainable strategies for agricultural sector in response to current environmental challenges. For water shortage problems, which are becoming more and more frequent worldwide including Taiwan, measures for irrigation water, such as extending irrigation periods, decreasing number of irrigation application times, or rotational irrigation, are introduced and discussed. When borrowing or transfer of water among sectors is needed in Taiwan, it is usually from agricultural irrigation water to other sectors in almost all cases. The maintenance of water right, and compensation to farmers for their income loss, are the two major issues. As for environmental changes, the impact of the accession of Taiwan to WTO (World Trade Organization) is discussed specifically in this article, and a management scheme in order to save irrigation water, which could be used for other purposes, is suggested in this article

Engineering of Escherichia coli protein expression process development

It almost 30% protein drugs are expression by Escherichia coli, because of rapid growth and high production yield. We have developed E.coli base system for recombinant protein expression, scFv, Fab and vaccine. In this study we introduce example about process development for nutrient components selection. Shaker flasks were used for different nitrogen and carbon components screening by DoE. Seven media formulations for E. coli fermentation were used in this study. By changing nitrogen and carbon source ratio, product titer of target protein could be optimized, at least 1.4 folds increased. The best result from shaker flask was used in 250 mL parallel fermenter and pH, dissolved oxygen, feeding/induction strategy were evaluated. The processes from seed culture to harvest only require 64 hours. The optimized time was reduced to 32 hours. The result showed that both target protein expression and cell density value were comparable, but the total process time was significantly reduced by half Please click Additional Files below to see the full abstract

Nonlinear photoacoustic microscopy via a loss modulation technique: from detection to imaging

In order to achieve high-resolution deep-tissue imaging, multi-photon fluorescence microscopy and photoacoustic tomography had been proposed in the past two decades. However, combining the advantages of these two imaging systems to achieve optical-spatial resolution with an ultrasonic-penetration depth is still a field with challenges. In this paper, we investigate the detection of the two-photon photoacoustic ultrasound, and first demonstrate background-free two-photon photoacoustic imaging in a phantom sample. To generate the background-free two-photon photoacoustic signals, we used a high-repetition rate femtosecond laser to induce narrowband excitation. Combining a loss modulation technique, we successfully created a beating on the light intensity, which not only provides pure sinusoidal modulation, but also ensures the spectrum sensitivity and frequency selectivity. By using the lock-in detection, the power dependency experiment validates our methodology to frequency-select the source of the nonlinearity. This ensures our capability of measuring the background-free two-photon photoacoustic waves by detecting the 2nd order beating signal directly. Furthermore, by mixing the nanoparticles and fluorescence dyes as contrast agents, the two-photon photoacoustic signal was found to be enhanced and detected. In the end, we demonstrate subsurface two-photon photoacoustic bio-imaging based on the optical scanning mechanism inside phantom samples

Sorafenib for hepatocellular carcinoma patients beyond Milan criteria after orthotopic liver transplantation: a case control study

<p>Abstract</p> <p>Background</p> <p>Orthotopic liver transplantation (OLT) is one of the most effective treatments for patients with hepatocellular carcinoma (HCC) within the Milan criteria. However, for patients beyond these criteria, the recurrence rate is higher and the prognosis is worse. Sorafenib is the only drug showing survival benefits in advanced HCC patients; however, its role in patients beyond the Milan criteria after OLT remains unclear and requires further investigation.</p> <p>Methods</p> <p>As a case-control study, we retrospectively analyzed 17 Chinese patients beyond Milan criteria undergoing OLT for HCC. These patients were stratified into adjuvant (n = 5), palliative (n = 6), and control groups (n = 6).</p> <p>Results</p> <p>Nine of 11 patients who received sorafenib after OLT needed dose reduction due to more than grade 2 side effects. The disease-free survival rates for patients with or without adjuvant sorafenib were 100% versus 37.5% (p = 0.034) at 6 months, 66.7% versus 9.4% (p = 0.026) at 12 months, and 66.7% versus 0.0% (p = 0.011) at 18 months, respectively. The overall survival rates for patients in palliative and control groups were 66.7% versus 40.0% (p = 0.248) at 6 months, 66.7% versus 40.0% (p = 0.248) at 12 months, and 50.0% versus 20.0% (p = 0.17) at 18 months, respectively. Patients in the adjuvant group had better overall survival rates than those in the palliative and control groups (p = 0.031) at 24-month follow-up.</p> <p>Conclusions</p> <p>Adjuvant sorafenib could possibly extend both disease-free and overall survival for HCC patients beyond Milan criteria after OLT.</p