气功锻炼对高血压患者作用的研究进展

2007-2008 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Analysis on the epidemiology and community interventions of hypertension

2007-2008 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Development of a culturally sensitive life review program for Chinese patients with advanced cancer

2010-2011 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

社区中年高血压患者认知行为的调查研究

2007-2008 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

高血压病的中医发病观

2007-2008 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

A survey on health-promoting lifestyle among community-dwelling older people with hypertension in Macau

2007-2008 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Daphnia revisited: Local stability and bifurcation theory for physiologically structured population models explained by way of an example

We consider the interaction between a general size-structured consumer population and an unstructured resource. We show that stability properties and bifurcation phenomena can be understood in terms of solutions of a system of two delay equations (a renewal equation for the consumer population birth rate coupled to a delay differetial equation for the resource concentration). As many results for such systems are available, we can draw rigorous conclusions concerning dynamical behaviour from an analysis of a characteristic equation. We derive the characteristic equation for a fairly general class of population models, including those based on the Kooijman-Metz Daphnia model and a model introduced by Gurney-Nisbet and Jones et al., and next obtain various ecological insights by analytical or numerical studies of special cases

Predicting pressure sore risk with the Braden(modified),Norton and WCUMS Scales

2003-2004 > Academic research: refereed > Publication in refereed journalVersion of RecordPublishe

Aflatoxin-Induced TP53 R249S Mutation in HepatoCellular Carcinoma in Thailand: Association with Tumors Developing in the Absence of Liver Cirrhosis

Primary Liver Cancer (PLC) is the leading cause of death by cancer among males in Thailand and the 3rd among females. Most cases are hepatocellular carcinoma (HCC) but cholangiocarcinomas represent between 4 and 80% of liver cancers depending upon geographic area. Most HCC are associated with chronic infection by Hepatitis B Virus while a G→T mutation at codon 249 of the TP53 gene, R249S, specific for exposure to aflatoxin, is detected in tumors for up to 30% of cases. We have used Short Oligonucleotide Mass Analysis (SOMA) to quantify free circulating R249S-mutated DNA in plasma using blood specimens collected in a hospital case:control study. Plasma R249S-mutated DNA was detectable at low concentrations (≥67 copies/mL) in 53 to 64% of patients with primary liver cancer or chronic liver disease and in 19% of controls. 44% of patients with HCC and no evidence of cirrhosis had plasma concentrations of R249S-mutated DNA ≥150 copies/mL, compared to 21% in patients with both HCC and cirrhosis, 22% in patients with cholangiocarcinoma, 12% in patients with non-cancer chronic liver disease and 3% of subjects in the reference group. Thus, plasma concentrations of R249S-mutated DNA ≥150 copies/mL tended to be more common in patients with HCC developing without pre-existing cirrhosis (p = 0.027). Overall, these results support the preferential occurrence of R249S-mutated DNA in HCC developing in the absence of cirrhosis in a context of HBV chronic infection