Diagnostic accuracy of LAMP, Xpert® MTB/RIF and fluorescence smear microscopy and cost per test at different batch sizes (n = 233).

<p>Diagnostic accuracy of LAMP, Xpert® MTB/RIF and fluorescence smear microscopy and cost per test at different batch sizes (n = 233).</p

Laboratory workflow.

<p>Abbreviations: LAMP = Loop-mediated Isothermal Amplification assay; FM = fluorescence microscopy; MGIT = Mycobacteria Growth Indicator Tube; LJ = Lowenstein Jensen media; NALC-NaOH = n-acetyl-L-cysteine (NALC)—sodium hydroxide (NaOH). ^a Preference was given to investigations for ‘sputum 1’ in case of inadequate volume or salivary specimen of one or more samples, since culture results were the predefined reference standard.</p

Studies of accuracy of LAMP for diagnosis of tuberculosis.

<p>Abbreviations: TP = true positive; FP = false positive; FN = false negative; TN = true negative. Study setting: ¹ Primary care; ² Hospital; ³ University or national reference laboratory. ^a Refers to findings of this study in Malawi.^b Study sites were in Peru, Bangladesh, Tanzania.</p

Sensitivity and specificity of LAMP (compared to MGIT) by HIV status and smear status (n = 233).

<p>Sensitivity and specificity of LAMP (compared to MGIT) by HIV status and smear status (n = 233).</p

Baseline characteristics and tuberculosis and HIV diagnostic outcomes.

<p>Baseline characteristics and tuberculosis and HIV diagnostic outcomes.</p

Sensitivity analysis-impact of misclassification of diabetes on its association with members of households with TB.

Sensitivity analysis-impact of misclassification of diabetes on its association with members of households with TB.</p

Alcohol drinking twice per week or more in members of households with TB compared to those without TB.

Alcohol drinking twice per week or more in members of households with TB compared to those without TB.</p

Association between BMI of people with TB and the same in their household members.

Association between BMI of people with TB and the same in their household members.</p

Proportion of missing data by variable and survey.

Proportion of missing data by variable and survey.</p

Sensitivity analysis- prevalence of NCD/NCD risk factors in members of households with TB compared to those without TB.

Sensitivity analysis- prevalence of NCD/NCD risk factors in members of households with TB compared to those without TB.</p