2,086 research outputs found
Escalation of error catastrophe for enzymatic self-replicators
It is a long-standing question in origin-of-life research whether the
information content of replicating molecules can be maintained in the presence
of replication errors. Extending standard quasispecies models of non-enzymatic
replication, we analyze highly specific enzymatic self-replication mediated
through an otherwise neutral recognition region, which leads to
frequency-dependent replication rates. We find a significant reduction of the
maximally tolerable error rate, because the replication rate of the fittest
molecules decreases with the fraction of functional enzymes. Our analysis is
extended to hypercyclic couplings as an example for catalytic networks.Comment: 6 pages, 4 figures; accepted at Europhys. Let
Records and sequences of records from random variables with a linear trend
We consider records and sequences of records drawn from discrete time series
of the form , where the are independent and identically
distributed random variables and is a constant drift. For very small and
very large drift velocities, we investigate the asymptotic behavior of the
probability of a record occurring in the th step and the
probability that all entries are records, i.e. that . Our work is motivated by the analysis of temperature time series in
climatology, and by the study of mutational pathways in evolutionary biology.Comment: 21 pages, 7 figure
Bottleneck-induced transitions in a minimal model for intracellular transport
We consider the influence of disorder on the non-equilibrium steady state of
a minimal model for intracellular transport. In this model particles move
unidirectionally according to the \emph{totally asymmetric exclusion process}
(TASEP) and are coupled to a bulk reservoir by \emph{Langmuir kinetics}. Our
discussion focuses on localized point defects acting as a bottleneck for the
particle transport. Combining analytic methods and numerical simulations, we
identify a rich phase behavior as a function of the defect strength. Our
analytical approach relies on an effective mean-field theory obtained by
splitting the lattice into two subsystems, which are effectively connected
exploiting the local current conservation. Introducing the key concept of a
carrying capacity, the maximal current which can flow through the bulk of the
system (including the defect), we discriminate between the cases where the
defect is irrelevant and those where it acts as a bottleneck and induces
various novel phases (called {\it bottleneck phases}). Contrary to the simple
TASEP in the presence of inhomogeneities, many scenarios emerge and translate
into rich underlying phase-diagrams, the topological properties of which are
discussed.Comment: 14 pages, 15 figures, 1 tabl
Kinetic roughening of surfaces: Derivation, solution and application of linear growth equations
We present a comprehensive analysis of a linear growth model, which combines
the characteristic features of the Edwards--Wilkinson and noisy Mullins
equations. This model can be derived from microscopics and it describes the
relaxation and growth of surfaces under conditions where the nonlinearities can
be neglected. We calculate in detail the surface width and various correlation
functions characterizing the model. In particular, we study the crossover
scaling of these functions between the two limits described by the combined
equation. Also, we study the effect of colored and conserved noise on the
growth exponents, and the effect of different initial conditions. The
contribution of a rough substrate to the surface width is shown to decay
universally as , where is
the time--dependent correlation length associated with the growth process,
is the initial roughness and the correlation length of the
substrate roughness, and is the surface dimensionality. As a second
application, we compute the large distance asymptotics of the height
correlation function and show that it differs qualitatively from the functional
forms commonly used in the intepretation of scattering experiments.Comment: 28 pages with 4 PostScript figures, uses titlepage.sty; to appear in
Phys. Rev.
Stretched exponentials and power laws in granular avalanching
We introduce a model for granular avalanching which exhibits both stretched exponential and power law avalanching over its parameter range. Two modes of transport are incorporated, a rolling layer consisting of individual particles and the overdamped, sliding motion of particle clusters. The crossover in behaviour observed in experiments on piles of rice is attributed to a change in the dominant mode of transport. We predict that power law avalanching will be observed whenever surface flow is dominated by clustered motion.
Comment: 8 pages, more concise and some points clarified
Numerical study of a non-equilibrium interface model
We have carried out extensive computer simulations of one-dimensional models
related to the low noise (solid-on-solid) non-equilibrium interface of a two
dimensional anchored Toom model with unbiased and biased noise. For the
unbiased case the computed fluctuations of the interface in this limit provide
new numerical evidence for the logarithmic correction to the subnormal L^(1/2)
variance which was predicted by the dynamic renormalization group calculations
on the modified Edwards-Wilkinson equation. In the biased case the simulations
are in close quantitative agreement with the predictions of the Collective
Variable Approximation (CVA), which gives the same L^(2/3) behavior of the
variance as the KPZ equation.Comment: 15 pages revtex, 4 Postscript Figure
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