80 research outputs found
Predictive value of the acid fast smear for detection of Mycobacterium tuberculosis in respiratory specimens in a Reference Center of HIV/Aids in Rio de Janeiro, Brazil
Peculiaridades do controle da tuberculose em um cenário de violência urbana de uma comunidade carente do Rio de Janeiro
Publicações na área de tisiologia no Jornal Brasileiro de Pneumologia entre 2004 e 2011: tipos de artigos, modelos de estudo, grau de evidência científica e impacto social
Cost-effectiveness analysis of PCR for the rapid diagnosis of pulmonary tuberculosis
<p>Abstract</p> <p>Background</p> <p>Tuberculosis is one of the most prominent health problems in the world, causing 1.75 million deaths each year. Rapid clinical diagnosis is important in patients who have co-morbidities such as Human Immunodeficiency Virus (HIV) infection. Direct microscopy has low sensitivity and culture takes 3 to 6 weeks <abbrgrp><abbr bid="B1">1</abbr><abbr bid="B2">2</abbr><abbr bid="B3">3</abbr></abbrgrp>. Therefore, new tools for TB diagnosis are necessary, especially in health settings with a high prevalence of HIV/TB co-infection.</p> <p>Methods</p> <p>In a public reference TB/HIV hospital in Brazil, we compared the cost-effectiveness of diagnostic strategies for diagnosis of pulmonary TB: Acid fast bacilli smear microscopy by Ziehl-Neelsen staining (AFB smear) plus culture and AFB smear plus colorimetric test (PCR dot-blot).</p> <p>From May 2003 to May 2004, sputum was collected consecutively from PTB suspects attending the Parthenon Reference Hospital. Sputum samples were examined by AFB smear, culture, and PCR dot-blot. The gold standard was a positive culture combined with the definition of clinical PTB. Cost analysis included health services and patient costs.</p> <p>Results</p> <p>The AFB smear plus PCR dot-blot require the lowest laboratory investment for equipment (US 5,635,760 versus US 50,773 and US 374,778,045 and US$ 110,849,055, respectively.</p> <p>Conclusion</p> <p>AFB smear associated with PCR dot-blot associated has the potential to be a cost-effective tool in the fight against PTB for patients attended in the TB/HIV reference hospital.</p
Participação internacional em estudos colaborativos publicados em revistas de pneumologia: onde está o Jornal Brasileiro de Pneumologia?
Estudo dinâmico da mortalidade por tuberculose no Estado de São Paulo, Brasil: uma abordagem bayesiana
Prevalence of mycobacterium tuberculosis among professionals in a university hospital, Mato Grosso do Sul, 2004
Evolução clínica de um grupo de pacientes com TB multirresistente atendidos em um centro de referência na cidade do Rio de Janeiro
Brazilian Response to Global End TB Strategy : The National Tuberculosis Research Agenda
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