Sucrose and cocaine self-administration data set

<p>This data set includes raw data for sucrose intake and cocaine self-administration experiments for all three rat strains used in our study – Trpc4-KO, wild-type and heterozygous animals. The sucrose intake data is over a 10-day period, while the cocaine self-administration data is 13 days. Both data sets include averages for the first 3 days and last three days of experiments, also shown in Figure 2. Catheter patency tests and lever press data is also included. Catheter patency was tested and recorded daily. Lever press data shows the total lever presses (inactive and active) for each animal, which will differ from number of drug infusions due to the time-out period between infusions.</p

Cocaine infusions earned before and during the dose-response challenge

<p>This data set represents the number of cocaine infusions each subject earned for the last two days preceding (2a), and for the two consecutive sessions during (2b), the dose-response challenge for mice of each genotype. TRPC5 +/+ = wild-type; TRPC5 -/- = knock-down; "-2" = second to last day leading up to dose-response challenge; "-1" = last day leading up to dose-response challenge; S(0.05) = session with dose 0.05 mg/kg/infusion; S(0.1) = session with dose 0.1 mg/kg/infusion; S(0.75) = session with dose 0.75 mg/kg/infusion; S(2.0) = session with does 2.0 mg/kg/infusion; S1 = first daily session with respective dose; S2 = second daily session with respective dose</p