11 research outputs found
Differences in cytokine levels between T1D patients with and without IA2A.
<p>Compared to T1D patients without IA2A, T1D patients with IA2A showed a tendency for higher GM-CSF (<b>A</b>), IL-1β (<b>B</b>), TNF-ɑ (<b>C</b>), IFN-γ (<b>D</b>), and IL-10 (<b>E</b>) levels Bonferroni correction<sup>*</sup>. Lines represent median and interquartile range values. <sup>*</sup> P-values ≤ 0.0025 were considered statistically significant after Bonferroni correction in Mann–Whitney <i>U</i>-test.</p
Cytokine associations with age and gender in the whole study group.
<p>Cytokine associations with age and gender in the whole study group.</p
Differences in cytokine levels between T1D patients with and without ZnT8A.
<p>Compared to T1D patients without ZnT8A, T1D patients with ZnT8A showed a tendency for higher GM-CSF (A) and IL-1β (B) levels after Bonferroni correction*. Lines represent median and interquartile range values. * P-values 0.05–0.0025 were considered as a tendency after Bonferroni correction in Mann–Whitney U-test.</p
Minimal detectable concentrations and percentage rates of detection for investigated cytokines.
<p>Minimal detectable concentrations and percentage rates of detection for investigated cytokines.</p
The correlation matrix of peripheral blood cytokine levels in T1D patients (part A) and control group (part B).
<p>The correlation matrix of peripheral blood cytokine levels in T1D patients (part A) and control group (part B).</p
Cytokine levels among controls and T1D patients.
<p>Cytokine levels among controls and T1D patients.</p
Differences in cytokine levels between T1D patients with and without ketoacidosis.
<p>Compared to T1D patients without ketoacidosis, patients with ketoacidosis had a tendency for higher IL-8 (A) and IL-10 levels after Bonferroni correction* (B). Lines represent median and interquartile range values. * P-values ≤ 0.0025 were considered statistically significant after Bonferroni correction in Mann-Whitney U-test.</p
Association of time between T1D diagnosis and blood sampling with cytokine levels.
<p>After the Bonferroni correction, the levels of IL-7 (A), TNF-ɑ (B), IL-8 (C), and IL-13 (D) showed a tendency to decrease with an increasing number of days between T1D diagnosis and blood sampling. Spearman’s rank correlation test was used.</p
Patients with multiple sclerosis (MS) characteristics.
<p><sup>1</sup> Interferon β i.e Betaferon®, Rebif® or Avonex®</p><p><sup>2</sup> Glatiramer acetate i.e Copaxone®</p><p><sup>3</sup> Cytostatics includes mitoxantrone and cyclophosphamide</p><p>Patients with multiple sclerosis (MS) characteristics.</p
Average BAFF plasma levels and disease-modifying treatments (DMT).
<p>Bee Swarm plot of BAFF level in untreated (UT), IFN-β, glatiramer acetate (GA) and immunosuppressant (IS)-treated groups were shown. Means and the results of Tukey HSD test are shown. *Average BAFF values during treatment were used. In case of medication change, the new average BAFF was analysed separately.</p