Development and Characterization of Soy Lecithin and Palm Oil-based Organogels

<div><p>Preparation and characterization of soy lecithin (SL) and palm oil (PO) based organogels have been reported in this study. The optimization of the composition of the organogels was carried out by varying the proportions of SL, PO and water. Microscopic studies suggested the presence of aqueous phase either as spherical droplets or fluid filled fibers or both, depending on the composition of the organogels. FTIR study indicated strong intermolecular hydrogen bonding among the organogel components. The release of metronidazole (model drug, MZ) suggested diffusion mediated drug release. MZ loaded organogels showed good antimicrobial property against <i>B. subtilis</i> and <i>E. coli.</i></p> </div

Preparation, Characterization and Assessment of the Novel Gelatin–tamarind Gum/Carboxymethyl Tamarind Gum-Based Phase-Separated Films for Skin Tissue Engineering Applications

<p>The current study delineates the development of novel gelatin–tamarind gum/carboxymethyl tamarind gum-based phase-separated films for probable skin tissue engineering applications. Polyethylene glycol was used as plasticizer. The films were characterized thoroughly using mechanical tester and impedance analyzer. Cell proliferation ability and drug release properties of the films were investigated. Mechanical studies indicated composition-dependent stress relaxation properties. Polysaccharide containing films supported better proliferation of human keratinocytes as compared to control. Drug-loaded films showed good antimicrobial properties against <i>Escherichia coli</i>. Analysis of the results indicated that the prepared films may be tried as matrices for skin tissue engineering.</p