Oral Medications to Treat Toenail Fungal Infection

Which oral antifungal medication is associated with the highest clinical (ie, normal appearance of the toenail) and mycological (negative culture, microscopy, or both) cure rates vs placebo or other antifungals when used to treat fungal infections?Both terbinafine and azole-based medications were associated with higher clinical and mycological cure rates compared with placebo (high-quality evidence). Azoles were associated with lower cure rates than terbinafine when compared directly

Chewing the fat over statins: Consumer concerns about lipid-lowering medication

Background and objectiv

Your questions about complementary medicines answered

This is the first article in a series providing evidence-based answers to common questions about complementary medicines from consumers and healthcare professionals

Treating chronic fatigue syndrome:A study into the scientific evidence for pharmacological treatments

Background : Chronic fatigue syndrome, or myalgic encephalomyelitis (CFS), is a severe disabling condition. Patients with CFS usually trial many different medicines, both conventional and complementary. An overview of the pharmacological treatments used by CFS patients and the available evidence underpinning the use of these treatments would be of great value to both patients and their healthcare providers. Methods : Ninety-four CFS patients recruited into an Australian study investigating immunological biomarkers filled out a questionnaire assessing the medicines they were taking. Evidence from randomised clinical trials was sought in biomedical databases. Results : The 94 CFS patients used 474 different medicines and supplements. The most commonly used medicines were antidepressants, analgesics, sedatives, and B vitamins. We identified 20 randomised controlled trials studying these medicines in CFS patients. Conclusion : While conventional and complementary medicines are widely used by CFS patients, the evidence for effectiveness in CFS is very limited

Your questions about complementary medicines answered: Ginkgo biloba

This is the fourth article in a series providing evidence-based answers to common questions about complementary medicines from consumers and healthcare professionals