3,348 research outputs found

    Z-boson as "the standard candle" for high precision W-boson physics at LHC

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    In this paper we propose a strategy for measuring the inclusive W-boson production processes at LHC. This strategy exploits simultaneously the unique flexibility of the LHC collider in running variable beam particle species at variable beam energies, and the configuration flexibility of the LHC detectors. We propose their concrete settings for a precision measurement of the Standard Model parameters. These dedicated settings optimise the use of the Z boson and Drell-Yan pair production processes as ``the standard reference candles''. The presented strategy allows to factorise and to directly measure those of the QCD effects which affect differently the W and Z production processes. It reduces to a level of 10^{-4} the impact of uncertainties in the partonic distribution functions (PDFs) and in the transverse momentum of the quarks on the measurement precision. Last but not the least, it reduces by a factor of 10 an impact of systematic measurement errors, such as the energy scale and the measurement resolution, on the W-boson production observables.Comment: 20 pages, 4 figure

    Cross Section Ratios between different CM energies at the LHC: opportunities for precision measurements and BSM sensitivity

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    The staged increase of the LHC beam energy provides a new class of interesting observables, namely ratios and double ratios of cross sections of various hard processes. The large degree of correlation of theoretical systematics in the cross section calculations at different energies leads to highly precise predictions for such ratios. We present in this letter few examples of such ratios, and discuss their possible implications, both in terms of opportunities for precision measurements and in terms of sensitivity to Beyond the Standard Model dynamics.Comment: 19 pages, 9 figure

    Spectroscopy at B-factories Using Hard Photon Emission

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    The process of hard photon emission by initial electrons (positrons) at B-factories is discussed. It is shown that studies of the bottomonium spectroscopy will be feasible for the planned integrated luminosity of the B-factory experiments.Comment: 9 pages, Latex, 1 fugure, Submitted to Int.Jour.Mod.Phys.

    Measurement of MW+ - MW- at LHC

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    This paper is the second of the series of papers proposing dedicated strategies for precision measurements of the Standard Model parameters at the LHC. The common feature of these strategies is their robustness with respect to the systematic measurement and modeling error sources. Their impact on the precision of the measured parameters is reduced using dedicated observables and dedicated measurement procedures which exploit flexibilities of the collider and detector running modes. In the present paper we focus our attention on the measurement of the charge asymmetry of the W-boson mass. This measurement is of primordial importance for the LHC experimental program, both as a direct test of the charge-sign-independent coupling of the W-bosons to the matter particles and as a necessary first step towards the precision measurement of the charge-averaged W-boson mass. We propose and evaluate the LHC-specific strategy to measure the mass difference between the positively and negatively charged W-bosons, MW+ - MW-. We show that its present precision can be improved at the LHC by a factor of 20. We argue that such a precision is beyond the reach of the standard measurement and calibration methods imported to the LHC from the Tevatron program.Comment: 39 pages, 8 figure

    Tagged-photon events in polarized DIS process

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    Deep-inelastic events for the scattering of the longitudinally polarized electron by polarized proton with tagged collinear photon radiated from initial-state electron are considered. The corresponding cross-section is derived in the Born approximation. The model-independent radiative corrections to the Born cross-section are also calculated. Obtained result is applied to the case of elastic scattering.Comment: 14 pages, 2 figures, submitted to JET

    ΠšΠ»ΠΈΠ½ΠΈΡ‡Π΅ΡΠΊΠΈΠ΅ аспСкты послСопСрационного ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚Π°, Ρ€Π°Π·Π²ΠΈΠ²ΡˆΠ΅Π³ΠΎΡΡ послС цистэктомии

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    Background. Surgical morbidities of radical cystectomy, which are, as a rule, complicated intraabdominal infections, appear to be the main causes of repeated surgeries and fatal outcomes. The elimination of the infection Indus and an-timicrobic therapy are the currently accepted standard of treatment for postoperative peritonitis in cancer urology, as well as in general surgery hospital.Objective: defining the most reasonable option of surgical aid for peritonitis developing after cystectomy.Materials and methods. In the time period from 2000 through 2014, 58 cancer patients with postoperative peritonitis developing after cystectomy received indoor treatment at N.N. Alexandrov Republican Research and Practical Center for Oncology and Medical Radiology. Their mean age was 64.9 years, the range 44-90 years, 53 (91.4 %) of them being male. Primary urinary bladder cancer was present in 51 (87.9 %) patients. Peritoneal infection was microbiologically verified in 57 (98.3 %) patients. Each case of fatal outcome was associated with ineffective treatment of peritonitis. Depending on the intraoperative findings (presence or absence of a hollow organ defect) and the surgical approach undertaken (obstructive resection or operation maintaining the continuity of the intestinal and/or urinary tract), the patients were stratified into three groups: group 1 (n = 28), group 2 (n = 20) and group 3 (n = 10). There were no significant differences in the basic parameters specifying peritoneal infection severity between the patients of groups 1 and 2 vs group 3 (p >0.05).Results. Overall mortality amounted to 25.9 %, 15 patients died. Among the 28 (48.3 %) patients (group 1) who underwent obstructive elimination of the peritonitis focus by means of urointestinal reservoir ablation, resection of small or large intestine with ileo- or colostomy, 6 patients died, mortality 21.4 %. In the 10 (17.2 %) patients (group 3) who succeeded in preserving the urinary conduit or continuity of the bowels by anastomosis defect closure, resection of enteroentero-anastomosis or urointestinal reservoir with repeated anastomosing or defect closure, mortality was higher (60 %) (p = 0.045); 6 patients died.Conclusion. The most effective option of surgical treatment of postoperative peritonitis developing after cystectomy is obstructive reoperation on the bowels and urinary tracts: compared with the intervention consisting in preserving the urinary conduit and/or continuity of the intestinal tract, this type of surgery caused a 2.8-fold lower mortality.Π’Π²Π΅Π΄Π΅Π½ΠΈΠ΅. Π₯ирургичСскиС ослоТнСния Ρ€Π°Π΄ΠΈΠΊΠ°Π»ΡŒΠ½ΠΎΠΉ цистэктомии, Ρ‚Π°ΠΊΠΈΠ΅ ΠΊΠ°ΠΊ ослоТнСнныС ΠΈΠ½Ρ‚Ρ€Π°Π°Π±Π΄ΠΎΠΌΠΈΠ½Π°Π»ΡŒΠ½Ρ‹Π΅ ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ ΠΈ ΠΊΠΈΡˆΠ΅Ρ‡Π½Π°Ρ Π½Π΅ΠΏΡ€ΠΎΡ…ΠΎΠ΄ΠΈΠΌΠΎΡΡ‚ΡŒ, - основныС ΠΏΡ€ΠΈΡ‡ΠΈΠ½Ρ‹ ΠΏΠΎΠ²Ρ‚ΠΎΡ€Π½Ρ‹Ρ… ΠΎΠΏΠ΅Ρ€Π°Ρ†ΠΈΠΉ ΠΈ Π»Π΅Ρ‚Π°Π»ΡŒΠ½Ρ‹Ρ… исходов. ΠžΠ±Ρ‰Π΅ΠΏΡ€ΠΈΠ½ΡΡ‚Ρ‹ΠΌ стандартом лСчСния послСопСрационного ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚Π° Π² ΠΎΠ½ΠΊΠΎΡƒΡ€ΠΎΠ»ΠΎΠ³ΠΈΠΈ, ΠΊΠ°ΠΊ ΠΈ Π² общСхирургичСском стационарС, ΡΠ²Π»ΡΡŽΡ‚ΡΡ устранСниС ΠΎΡ‡Π°Π³Π° ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ ΠΈ антимикробная тСрапия.ЦСль исслСдования - ΠΎΠΏΡ€Π΅Π΄Π΅Π»ΠΈΡ‚ΡŒ Π½Π°ΠΈΠ±ΠΎΠ»Π΅Π΅ ΠΏΡ€ΠΈΠ΅ΠΌΠ»Π΅ΠΌΡ‹ΠΉ Π²Π°Ρ€ΠΈΠ°Π½Ρ‚ хирургичСского пособия ΠΏΡ€ΠΈ ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚Π΅, Ρ€Π°Π·Π²ΠΈΠ²ΡˆΠ΅ΠΌΡΡ послС цистэктомии.ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹. Π’ ΠΏΠ΅Ρ€ΠΈΠΎΠ΄ с 2000 ΠΏΠΎ 2014 Π³. Π² РСспубликанском Π½Π°ΡƒΡ‡Π½ΠΎ-практичСском Ρ†Π΅Π½Ρ‚Ρ€Π΅ ΠΎΠ½ΠΊΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΈ мСдицинской Ρ€Π°Π΄ΠΈΠΎΠ»ΠΎΠ³ΠΈΠΈ ΠΈΠΌ. Н.Н. АлСксандрова Π½Π° стационарном Π»Π΅Ρ‡Π΅Π½ΠΈΠΈ Π½Π°Ρ…ΠΎΠ΄ΠΈΠ»ΠΈΡΡŒ 58 онкологичСских ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² (ΠΈΠ· Π½ΠΈΡ… 53 (91,4 %) ΠΌΡƒΠΆΡ‡ΠΈΠ½Ρ‹) с послСопСрационным ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚ΠΎΠΌ, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹ΠΉ развился послС цистэктомии. Π‘Ρ€Π΅Π΄Π½ΠΈΠΉ возраст - 64,9 (44-90) Π³ΠΎΠ΄Π°. ΠŸΠ΅Ρ€Π²ΠΈΡ‡Π½Ρ‹ΠΉ Ρ€Π°ΠΊ ΠΌΠΎΡ‡Π΅Π²ΠΎΠ³ΠΎ пузыря зарСгистрирован Ρƒ 51 (87,9 %) ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π°. ΠœΠΈΠΊΡ€ΠΎΠ±ΠΈΠΎΠ»ΠΎΠ³ΠΈΡ‡Π΅ΡΠΊΠΎΠ΅ ΠΏΠΎΠ΄Ρ‚Π²Π΅Ρ€ΠΆΠ΄Π΅Π½ΠΈΠ΅ ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ Π±Ρ€ΡŽΡˆΠΈΠ½Ρ‹ имСлось Ρƒ 57 (98,3 %) ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ². ΠšΠ°ΠΆΠ΄Ρ‹ΠΉ случай Π»Π΅Ρ‚Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ исхода ассоциирован с Π½Π΅ΡΡ„Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒΡŽ лСчСния ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚Π°. Π’ зависимости ΠΎΡ‚ ΠΈΠ½Ρ‚Ρ€Π°ΠΎΠΏΠ΅Ρ€Π°Ρ†ΠΈΠΎΠ½Π½Ρ‹Ρ… Π΄Π°Π½Π½Ρ‹Ρ… (Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ ΠΈΠ»ΠΈ отсутствиС Π΄Π΅Ρ„Π΅ΠΊΡ‚Π° ΠΏΠΎΠ»ΠΎΠ³ΠΎ ΠΎΡ€Π³Π°Π½Π°) ΠΈ прСдпринятой хирургичСской Ρ‚Π°ΠΊΡ‚ΠΈΠΊΠΈ (обструктивная рСзСкция ΠΈΠ»ΠΈ опСрация с сохранСниСм нСпрСрывности ΠΊΠΈΡˆΠ΅Ρ‡Π½ΠΎΠ³ΠΎ ΠΈ/ΠΈΠ»ΠΈ ΠΌΠΎΡ‡Π΅Π²ΠΎΠ³ΠΎ Ρ‚Ρ€Π°ΠΊΡ‚Π°) ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Ρ‹ Π±Ρ‹Π»ΠΈ стратифицированы Π½Π° 3 Π³Ρ€ΡƒΠΏΠΏΡ‹: Π² 1-ю Π³Ρ€ΡƒΠΏΠΏΡƒ вошли 28 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ², Π²ΠΎ 2-ю - 20, Π² 3-ю - 10. БущСствСнных Ρ€Π°Π·Π»ΠΈΡ‡ΠΈΠΉ ΠΏΠΎ основным ΠΏΠ°Ρ€Π°ΠΌΠ΅Ρ‚Ρ€Π°ΠΌ, Ρ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€ΠΈΠ·ΡƒΡŽΡ‰ΠΈΠΌ Ρ‚ΡΠΆΠ΅ΡΡ‚ΡŒ ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½Π΅Π°Π»ΡŒΠ½ΠΎΠΉ ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ, срСди ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² 1-ΠΉ ΠΈ 2-ΠΉ Π³Ρ€ΡƒΠΏΠΏ ΠΏΠΎ ΡΡ€Π°Π²Π½Π΅Π½ΠΈΡŽ с 3-ΠΉ Π½Π΅ Π±Ρ‹Π»ΠΎ (Ρ€ >0,05).Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹. ΠžΠ±Ρ‰Π°Ρ Π»Π΅Ρ‚Π°Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ составила 25,9 %; ΡƒΠΌΠ΅Ρ€Π»ΠΈ 15 Ρ‡Π΅Π»ΠΎΠ²Π΅ΠΊ. Π‘Ρ€Π΅Π΄ΠΈ 28 (48,3 %) ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² 1-ΠΉ Π³Ρ€ΡƒΠΏΠΏΡ‹, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹ΠΌ Π»ΠΈΠΊΠ²ΠΈΠ΄Π°Ρ†ΠΈΡŽ источника ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚Π° ΠΏΡ€ΠΎΠ²ΠΎΠ΄ΠΈΠ»ΠΈ ΠΏΠΎ обструктивному Ρ‚ΠΈΠΏΡƒ ΠΏΡƒΡ‚Π΅ΠΌ удалСния ΠΌΠΎΡ‡Π΅ΠΊΠΈΡˆΠ΅Ρ‡Π½ΠΎΠ³ΠΎ Ρ€Π΅Π·Π΅Ρ€Π²ΡƒΠ°Ρ€Π°, Ρ€Π΅Π·Π΅ΠΊΡ†ΠΈΠ΅ΠΉ Ρ‚ΠΎΠ½ΠΊΠΎΠ³ΠΎ ΠΈΠ»ΠΈ толстого ΠΊΠΈΡˆΠ΅Ρ‡Π½ΠΈΠΊΠ° с ΠΈΠ»Π΅ΠΎ- ΠΈΠ»ΠΈ колостомиСй, ΡƒΠΌΠ΅Ρ€Π»ΠΈ 6 Ρ‡Π΅Π»ΠΎΠ²Π΅ΠΊ; Π»Π΅Ρ‚Π°Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ - 21,4 %. Из 10 (17,2 %) ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² 3-ΠΉ Π³Ρ€ΡƒΠΏΠΏΡ‹, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹ΠΌ ΡƒΠ΄Π°Π»ΠΎΡΡŒ ΡΠΎΡ…Ρ€Π°Π½ΠΈΡ‚ΡŒ ΠΌΠΎΡ‡Π΅Π²ΠΎΠΉ ΠΊΠΎΠ½Π΄ΡƒΠΈΡ‚ ΠΈΠ»ΠΈ Π½Π΅ΠΏΡ€Π΅Ρ€Ρ‹Π²Π½ΠΎΡΡ‚ΡŒ ΠΊΠΈΡˆΠ΅Ρ‡Π½ΠΈΠΊΠ° ΡƒΡˆΠΈΠ²Π°Π½ΠΈΠ΅ΠΌ Π΄Π΅Ρ„Π΅ΠΊΡ‚Π° Π² анастомозС, Ρ€Π΅Π·Π΅ΠΊΡ†ΠΈΠ΅ΠΉ ΠΌΠ΅ΠΆΠΊΠΈΡˆΠ΅Ρ‡Π½ΠΎΠ³ΠΎ ΡΠΎΡƒΡΡ‚ΡŒΡ ΠΈΠ»ΠΈ ΠΌΠΎΡ‡Π΅ΠΊΠΈΡˆΠ΅Ρ‡Π½ΠΎΠ³ΠΎ Ρ€Π΅Π·Π΅Ρ€Π²ΡƒΠ°Ρ€Π° с ΠΏΠΎΠ²Ρ‚ΠΎΡ€Π½Ρ‹ΠΌ анастомозированиСм ΠΈΠ»ΠΈ ΡƒΡˆΠΈΠ²Π°Π½ΠΈΠ΅ΠΌ Π΄Π΅Ρ„Π΅ΠΊΡ‚Π°, Π»Π΅Ρ‚Π°Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ Π±Ρ‹Π»Π° Π²Ρ‹ΡˆΠ΅ - 60 % (Ρ€ = 0,045); ΡƒΠΌΠ΅Ρ€Π»ΠΈ 6 Ρ‡Π΅Π»ΠΎΠ²Π΅ΠΊ.Π—Π°ΠΊΠ»ΡŽΡ‡Π΅Π½ΠΈΠ΅. НаиболСС Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΈΠ²Π½Ρ‹ΠΌ Π²Π°Ρ€ΠΈΠ°Π½Ρ‚ΠΎΠΌ хирургичСского лСчСния послСопСрационного ΠΏΠ΅Ρ€ΠΈΡ‚ΠΎΠ½ΠΈΡ‚Π°, Ρ€Π°Π·Π²ΠΈΠ²ΡˆΠ΅Π³ΠΎΡΡ послС цистэктомии, являСтся обструктивная рСопСрация Π½Π° ΠΊΠΈΡˆΠ΅Ρ‡Π½ΠΈΠΊΠ΅ ΠΈ ΠΌΠΎΡ‡Π΅Π²Ρ‹Ρ… путях. По ΡΡ€Π°Π²Π½Π΅Π½ΠΈΡŽ с Π²ΠΌΠ΅ΡˆΠ°Ρ‚Π΅Π»ΡŒΡΡ‚Π²ΠΎΠΌ, состоящим Π² сохранСнии ΠΌΠΎΡ‡Π΅Π²ΠΎΠ³ΠΎ ΠΊΠΎΠ½Π΄ΡƒΠΈΡ‚Π° ΠΈ/ΠΈΠ»ΠΈ нСпрСрывности ΠΊΠΈΡˆΠ΅Ρ‡Π½ΠΎΠ³ΠΎ Ρ‚Ρ€Π°ΠΊΡ‚Π°, ΠΏΡ€ΠΈ Π΄Π°Π½Π½ΠΎΠΌ Ρ‚ΠΈΠΏΠ΅ ΠΎΠΏΠ΅Ρ€Π°Ρ†ΠΈΠΈ Π»Π΅Ρ‚Π°Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ Π±Ρ‹Π»Π° Π² 2,8 Ρ€Π°Π·Π° Π½ΠΈΠΆΠ΅

    Роль Π½Π°ΡƒΡ‡Π½Ρ‹Ρ… исслСдований Π² ΡƒΠ»ΡƒΡ‡ΡˆΠ΅Π½ΠΈΠΈ онкологичСской слуТбы ΠΈ направлСния дальнСйшСго ΡΠΎΠ²Π΅Ρ€ΡˆΠ΅Π½ΡΡ‚Π²ΠΎΠ²Π°Π½ΠΈΡ мСдицинской Π½Π° ΡƒΠΊΠΈ

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    This paper deals with the analysis of current trends in world cancer science and with a search for ways to intensify the development of RussianΒ oncology. It summarizes the results of the development of cancer science in the last 10 years and formulates main problems and handicaps onΒ the way of its further development in order to make reasoned decisions to reform the system and to create a development strategy for the nextΒ decade.ΠŸΡƒΠ±Π»ΠΈΠΊΠ°Ρ†ΠΈΡ посвящСна Π°Π½Π°Π»ΠΈΠ·Ρƒ соврСмСнных Ρ‚Π΅Π½Π΄Π΅Π½Ρ†ΠΈΠΉ Π² ΠΌΠΈΡ€ΠΎΠ²ΠΎΠΉ онкологичСской Π½Π°ΡƒΠΊΠ΅ ΠΈ поиску ΠΏΡƒΡ‚Π΅ΠΉ интСнсификации развития отСчСствСнной ΠΎΠ½ΠΊΠΎΠ»ΠΎΠ³ΠΈΠΈ. ΠŸΠΎΠ΄Π²Π΅Π΄Π΅Π½Ρ‹ ΠΈΡ‚ΠΎΠ³ΠΈ развития онкологичСской Π½Π°ΡƒΠΊΠΈ Π·Π° послСдниС 10 Π»Π΅Ρ‚, Π° Ρ‚Π°ΠΊΠΆΠ΅ сформулированы основныС ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΡ‹ ΠΈ прСпятствия Π½Π° ΠΏΡƒΡ‚ΠΈ Π΅Π΅ дальнСйшСго развития с Ρ†Π΅Π»ΡŒΡŽ принятия обоснованных Ρ€Π΅ΡˆΠ΅Π½ΠΈΠΉ ΠΏΠΎ Ρ€Π΅Ρ„ΠΎΡ€ΠΌΠΈΡ€ΠΎΠ²Π°Π½ΠΈΡŽΒ ΡΠΈΡΡ‚Π΅ΠΌΡ‹ ΠΈ Ρ„ΠΎΡ€ΠΌΠΈΡ€ΠΎΠ²Π°Π½ΠΈΡŽ стратСгии развития Π½Π° ΡΠ»Π΅Π΄ΡƒΡŽΡ‰Π΅Π΅ дСсятилСтиС

    ЀАКВОРЫ ΠŸΠ ΠžΠ“ΠΠžΠ—Π Π‘Π˜Π‘Π’Π•ΠœΠΠžΠ“Πž ΠŸΠ ΠžΠ“Π Π•Π‘Π‘Π˜Π ΠžΠ’ΠΠΠ˜Π― РАКА ΠŸΠ Π•Π”Π‘Π’ΠΠ’Π•Π›Π¬ΠΠžΠ™ Π–Π•Π›Π•Π—Π« Π£ ΠŸΠΠ¦Π˜Π•ΠΠ’ΠžΠ’ Π‘ Π‘Π˜ΠžΠ₯Π˜ΠœΠ˜Π§Π•Π‘ΠšΠ˜Πœ Π Π•Π¦Π˜Π”Π˜Π’ΠžΠœ ΠŸΠžΠ‘Π›Π• Π ΠΠ”Π˜ΠšΠΠ›Π¬ΠΠžΠ™ ПРОБВАВЭКВОМИИ

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    The impact of different prognostics factors on the probability of development local and systemic relups in patient with biochemical recurrence following prostatectomy was studied. By multivariable analysis, predictors of systemic progression were seminal vesicle invasion (pT3b) (p = 0,005), trigger prostate-specific antigen level greater than 2 ng/mL (p = 0,03), prostate-specific antigen doubling time of 6 months or less (p = 0,002) and prostate-specific antigen velocity greater than 0,1 ng/mL per month (p < 0,0001). The rate of systemic progression in patient with not greater than one unfavorable predictor was 6,3 %, with two or greater predictors – 88,9 % (p < 0,001).Π˜Π·ΡƒΡ‡Π°Π»ΠΎΡΡŒ влияниС Ρ€Π°Π·Π»ΠΈΡ‡Π½Ρ‹Ρ… прогностичСских Ρ„Π°ΠΊΡ‚ΠΎΡ€ΠΎΠ² Π½Π° Π²Π΅Ρ€ΠΎΡΡ‚Π½ΠΎΡΡ‚ΡŒ выявлСния ΠΈΠ·ΠΎΠ»ΠΈΡ€ΠΎΠ²Π°Π½Π½ΠΎΠ³ΠΎ мСстного Ρ€Π΅Ρ†ΠΈΠ΄ΠΈΠ²Π° ΠΈΠ»ΠΈ систСмного прогрСссирования Ρ€Π°ΠΊΠ° ΠΏΡ€Π΅Π΄ΡΡ‚Π°Ρ‚Π΅Π»ΡŒΠ½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с биохимичСским Ρ€Π΅Ρ†ΠΈΠ΄ΠΈΠ²ΠΎΠΌ послС Ρ€Π°Π΄ΠΈΠΊΠ°Π»ΡŒΠ½ΠΎΠΉ простатэктомии. Π’ ΠΌΡƒΠ»ΡŒΡ‚ΠΈΠ²Π°Ρ€ΠΈΠ°Π½Ρ‚Π½ΠΎΠΌ Π°Π½Π°Π»ΠΈΠ·Π΅ Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ ΠΈΠ½Π²Π°Π·ΠΈΠΈ сСмСнных ΠΏΡƒΠ·Ρ‹Ρ€ΡŒΠΊΠΎΠ² ΠΏΠΎ Π΄Π°Π½Π½Ρ‹ΠΌ послСопСрационного морфологичСского исслСдования, ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ простатспСцифичСского Π°Π½Ρ‚ΠΈΠ³Π΅Π½Π° (ПБА) Π½Π° ΠΌΠΎΠΌΠ΅Π½Ρ‚ провСдСния обслСдования > 2 Π½Π³/ΠΌΠ», ΡΠΊΠΎΡ€ΠΎΡΡ‚ΡŒ прироста ПБА > 0,1 Π½Π³/ΠΌΠ» Π² мСсяц ΠΈ врСмя Π΅Π³ΠΎ удвоСния ≀ 6 мСс ΡΠ²Π»ΡΡŽΡ‚ΡΡ нСзависимыми Ρ„Π°ΠΊΡ‚ΠΎΡ€Π°ΠΌΠΈ, ассоциированными с высокой Π²Π΅Ρ€ΠΎΡΡ‚Π½ΠΎΡΡ‚ΡŒΡŽ наличия систСмного распространСния заболСвания Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с бСссимптомным ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½ΠΈΠ΅ΠΌ ПБА послС Ρ€Π°Π΄ΠΈΠΊΠ°Π»ΡŒΠ½ΠΎΠΉ простатэктомии (p < 0,05). Частота выявлСния систСмного распространСния процСсса ΠΏΡ€ΠΈ Π½Π°Π»ΠΈΡ‡ΠΈΠΈ Π΄Π²ΡƒΡ… ΠΈ Π±ΠΎΠ»Π΅Π΅ нСблагоприятных Ρ„Π°ΠΊΡ‚ΠΎΡ€ΠΎΠ² составила 88,9 %, ΠΏΡ€ΠΈ Π½Π°Π»ΠΈΡ‡ΠΈΠΈ Π½Π΅ Π±ΠΎΠ»Π΅Π΅ ΠΎΠ΄Π½ΠΎΠ³ΠΎ Ρ„Π°ΠΊΡ‚ΠΎΡ€Π° – 6,3 % (p < 0,001)

    Measurement and application of electron stripping of ultrarelativistic 208Pb81+^{208}\textrm{Pb}^{81+}

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    New measurements of the stripping cross-section for ultrarelativistic hydrogen-like lead ions passing through aluminium and silicon have been performed at the Advanced Wakefield experiment at CERN. Agreement with existing measurements and theory has been obtained. Improvements in terms of electron beam quality and ion beam diagnostic capability, as well as further applications of such an electron beam, are discussed
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