MOA: Massive Online Analysis, a framework for stream classification and clustering.

Massive Online Analysis (MOA) is a software environment for implementing algorithms and running experiments for online learning from evolving data streams. MOA is designed to deal with the challenging problem of scaling up the implementation of state of the art algorithms to real world dataset sizes. It contains collection of offline and online for both classification and clustering as well as tools for evaluation. In particular, for classification it implements boosting, bagging, and Hoeffding Trees, all with and without Naive Bayes classifiers at the leaves. For clustering, it implements StreamKM++, CluStream, ClusTree, Den-Stream, D-Stream and CobWeb. Researchers benefit from MOA by getting insights into workings and problems of different approaches, practitioners can easily apply and compare several algorithms to real world data set and settings. MOA supports bi-directional interaction with WEKA, the Waikato Environment for Knowledge Analysis, and is released under the GNU GPL license

Distanz zeigen, Nähe erzeugen

Between 1585 and 1600, Maerten de Vos, in cooperation with Jan and Raphael Sadeler and Adriaen Collaert, all active in the Antwerp print trade, published five series of engravings that show hermits in their hermitages. The 132 images in total put forward variations of one subject: the body techniques of asceticism pursued in places of isolation from everyday life. They create a paradoxical effect of making these distant places accessible and bringing them close to an audience. Through an in-depth analysis of the history and aesthetics of these prints, this article examines the reception of this outstanding project of early modern print culture. It shows how the series subtly convey a sense of the desert by visual means, thereby involving the viewers closely in the remote hermitages

Reliability of low-flow vasoreactivity in the brachial artery of adolescents

This is the author accepted manuscript. The final version is available from Wiley via the DOI in this recordPurpose: Macrovascular endothelial function is commonly assessed using flow-mediated dilation (FMD) and is nitric oxide (NO) dependent. However, the vasoreactivity to low flow during the FMD protocol may complement FMD interpretation. This study aimed to investigate in adolescents: (1) the day-to-day reliability of low-flow-mediated constriction (L-FMC) and composite vessel reactivity (CVR); and (2) the relationship between L-FMC and FMD. Methods: A retrospective analysis of data on 27 adolescents (14.3 ± 0.6 year, 12 males) was performed. Participants had two repeat measures, on separate days, of macrovascular function using high-resolution ultrasound for assessment of L-FMC, FMD, and CVR. Results: On average, the L-FMC response was vasoconstriction on both days (−0.59 ± 2.22% and −0.16 ± 1.50%, respectively). In contrast, an inconsistent response to low flow (vasoconstriction, dilation, or no change) was observed on an individual level. Cohen's Kappa revealed poor agreement for classifying the L-FMC measurement between visits (k = 0.04, P >.05). Assessment of the actual vessel diameter was robust with a coefficient of variation of 1.7% (baseline and peak) and 2.7% (low-flow). The between-day correlation coefficient between measures was r =.18, r =.96 and r =.52 for L-FMC, FMD, and CVR, respectively. No significant correlation between FMD and L-FMC was observed for either visit (r = −.06 and r = −.07, respectively; P >.05). Conclusion: In adolescents, the low-flow vasoreactivity is inconsistent between days. Whereas the actual vessel diameter is reproducible, the measurement of L-FMC and CVR has poor between-day reliability compared to FMD. Finally, L-FMC, and FMD are not significantly correlated

Effects of exercise intensity on vascular and autonomic components of the baroreflex following glucose ingestion in adolescents.

This is the final version. Available from the publisher via the DOI in this record.PURPOSE: To investigate the effects of an oral glucose tolerance test (OGTT) on baroreflex sensitivity (BRS) in a sample of healthy adolescents, and how acute exercise bouts of different intensities alter the effects of the OGTT on BRS. METHODS: Thirteen male adolescents (14.0 ± 0.5 years) completed three conditions on separate days in a counterbalanced order: (1) high-intensity interval exercise (HIIE); (2) moderate-intensity interval exercise (MIIE); and (3) resting control (CON). At ~ 90 min following the conditions, participants performed an OGTT. Supine heart rate and blood pressure were monitored continuously at baseline, 60 min following the conditions, and 60 min following the OGTT. A cross-spectral method (LFgain) was used to determine BRS gain. Arterial compliance (AC) was assessed as the BRS vascular component. LFgain divided by AC (LFgain/AC) was used as the autonomic component. RESULTS: Although non-significant, LFgain moderately decreased post-OGTT when no exercise was performed (pre-OGTT = 24.4 ± 8.2 ms mmHg- 1; post-OGTT = 19.9 ± 5.6 ms mmHg- 1; ES = 0.64, P > 0.05). This was attributed to the decrease in LFgain/AC (pre-OGTT = 1.19 ± 0.5 ms µm- 1; post-OGTT = 0.92 ± 0.24 ms µm- 1; ES = 0.69, P > 0.05). Compared to CON (Δ = - 4.4 ± 8.7 ms mmHg- 1), there were no differences for the pre-post-OGTT delta changes in LF/gain for HIIE (Δ = - 3.5 ± 8.2 ms mmHg- 1) and MIIE (Δ = 1.3 ± 9.9 ms mmHg- 1) had no effects on BRS following the OGTT (all ES < 0.5). Similarly, compared to CON (Δ = - 0.23 ± 0.40 ms µm- 1) there were no differences for the pre-post-OGTT delta changes in LF/gain for HIIE (Δ = - 0.22 ± 0.49 ms µm- 1) and MIIE (Δ = 0.13 ± 0.36 ms µm- 1). CONCLUSION: A moderate non-significant decrease in BRS was observed in adolescents following a glucose challenge with no apparent effects of exercise.Science Without Border

Trília: um jogo mobile de auxílio a depressivos

O trabalho aqui apresentado compreende o desenvolvimento tanto do game design quanto do projeto gráfico de Trília, um jogo mobile criado com o intuito de auxiliar pessoas com depressão ao longo de sua luta contra o transtorno. Este foi elaborado de forma a trabalhar concomitantemente aos tratamentos psicológicos e psiquiátricos comumente indicados a partir da aplicação de mecânicas baseadas em propostas de suporte social e de mudanças no estilo de vida dos jogadores em prol de uma melhoria em sua saúde física e mental