755 research outputs found
Quantitative predictions on auxin-induced polar distribution of PIN proteins during vein formation in leaves
The dynamic patterning of the plant hormone auxin and its efflux facilitator
the PIN protein are the key regulator for the spatial and temporal organization
of plant development. In particular auxin induces the polar localization of its
own efflux facilitator. Due to this positive feedback auxin flow is directed
and patterns of auxin and PIN arise. During the earliest stage of vein
initiation in leaves auxin accumulates in a single cell in a rim of epidermal
cells from which it flows into the ground meristem tissue of the leaf blade.
There the localized auxin supply yields the successive polarization of PIN
distribution along a strand of cells. We model the auxin and PIN dynamics
within cells with a minimal canalization model. Solving the model analytically
we uncover an excitable polarization front that triggers a polar distribution
of PIN proteins in cells. As polarization fronts may extend to opposing
directions from their initiation site we suggest a possible resolution to the
puzzling occurrence of bipolar cells, such we offer an explanation for the
development of closed, looped veins. Employing non-linear analysis we identify
the role of the contributing microscopic processes during polarization.
Furthermore, we deduce quantitative predictions on polarization fronts
establishing a route to determine the up to now largely unknown kinetic rates
of auxin and PIN dynamics.Comment: 9 pages, 4 figures, supplemental information included, accepted for
publication in Eur. Phys. J.
The occurrence and characterization of Campylobacter jejuni and C. coli in organic pigs and their outdoor environment
The occurrence and species distribution of thermophilic Campylobacter was investigated in organic outdoor pigs. An increased exposure of outdoor pigs to C. jejuni from the environment may cause a shift from a normal dominance of C. coli to more C. jejuni, which may imply a concern of reduced food safety.
Bacteriological methods for determination of Campylobacter excretion level were combined with colony-blot hybridization and real-time PCR for specific detection of C. jejuni in pigs. Campylobacter was isolated from pigs (n = 47), paddock environment (n = 126) and wildlife (n = 44), identified to species by real-time PCR and sub-typed by serotyping (Penner) and pulse-field gel electrophorsis (PFGE) genotyping.
All pigs excreted Campylobacter (103–107 CFU g1 faeces) from the age of 8–13-weeks old. C. jejuni was found in 29% of pigs in three consecutive trials and always in minority to C. coli (0.3–46%). C. jejuni and C. coli were isolated from 10% and 29% of the environmental samples, respectively, while crow-birds and rats harboured C. jejuni. Individual pigs hosted several strains (up to nine serotypes). The paddock environment was contaminated with C. coli serotypes similar to pig isolates, while most of the C. jejuni serotypes differed. C. jejuni isolates of different origin comprised few similar serotypes, just one identical genotype was common between pigs, environment and birds.
In conclusion, the occurrence of C. jejuni varied considerably between the three groups of outdoor pigs. Furthermore, transfer of C. jejuni to the outdoor pigs from the nearby environment was not predominant according to the subtype dissimilarities of the obtained isolates
The Magnetic Field of the Solar Corona from Pulsar Observations
We present a novel experiment with the capacity to independently measure both
the electron density and the magnetic field of the solar corona. We achieve
this through measurement of the excess Faraday rotation due to propagation of
the polarised emission from a number of pulsars through the magnetic field of
the solar corona. This method yields independent measures of the integrated
electron density, via dispersion of the pulsed signal and the magnetic field,
via the amount of Faraday rotation. In principle this allows the determination
of the integrated magnetic field through the solar corona along many lines of
sight without any assumptions regarding the electron density distribution. We
present a detection of an increase in the rotation measure of the pulsar
J18012304 of approximately 160 \rad at an elongation of 0.95 from
the centre of the solar disk. This corresponds to a lower limit of the magnetic
field strength along this line of sight of . The lack of
precision in the integrated electron density measurement restricts this result
to a limit, but application of coronal plasma models can further constrain this
to approximately 20mG, along a path passing 2.5 solar radii from the solar
limb. Which is consistent with predictions obtained using extensions to the
Source Surface models published by Wilcox Solar ObservatoryComment: 16 pages, 4 figures (1 colour): Submitted to Solar Physic
Elasticity-driven interaction between vortices in type-II superconductors
The contribution to the vortex lattice energy which is due to the
vortex-induced strains is calculated covering all the magnetic field range
which defines the vortex state. This contribution is compared with previously
reported ones what shows that, in the most part of the vortex state, it has
been notably underestimated until now. The reason of such underestimation is
the assumption that only the vortex cores induce strains. In contrast to what
is generally assumed, both core and non-core regions are important sources of
strains in high- superconductors.Comment: 10 pages, 1 figure, revtex
Permanent tooth agenesis in non-syndromic Robin sequence and cleft palate: prevalence and patterns
Objectives: Partial tooth agenesis is frequently observed in Robin sequence. Tooth anomalies are increasingly considered as an extended phenotype of the cleft palate population. The study objective was to compare the prevalence and patterns of tooth agenesis in a group of patients with non-syndromic Robin sequence (ns-RS) and a group with non-syndromic cleft palate (ns-CP). Materials and methods: The panoramic radiographs of 115 ns-RS and 191 ns-CP patients were assessed for agenesis of the permanent dentition (excluding third molars) and the patterns recorded using the Tooth Agenesis Code. Results: Partial tooth agenesis was observed in 47.8% of ns-RS and 29.8% of ns-CP patients with a greater prevalence in the mandibula than in the maxilla, particularly in ns-RS. The teeth most frequently absent in both groups were the mandibular second premolars and maxillary lateral incisors. Tooth agenesis was bilateral in two-thirds of affected ns-RS patients and one-half of ns-CP patients. In ns-RS, bilateral agenesis of the mandibular second premolars was more frequently observed in female than that in male patients. Completely symmetrical patterns of hypodontia were found in around 45% of ns-RS patients with tooth agenesis compared to 35% in ns-CP. No association was found between the extent of the palatal cleft and the severity of hypodontia. Conclusion: Tooth agenesis is more prevalent in ns-RS than that in ns-CP, demonstrates a much greater predilection for the mandible in ns-RS, and bears no relation to the extent of the palatal cleft. Clinical relevance: When compared to ns-CP, additional developmental disturbances are likely involved in the etiology of tooth agenesis in ns-RS. Future research could help identify the underlying genetic traits and aid in classifying patients in those with and without expected tooth agenesis in order to facilitate orthodontic management strategies
Phase Dynamics of Nearly Stationary Patterns in Activator-Inhibitor Systems
The slow dynamics of nearly stationary patterns in a FitzHugh-Nagumo model
are studied using a phase dynamics approach. A Cross-Newell phase equation
describing slow and weak modulations of periodic stationary solutions is
derived. The derivation applies to the bistable, excitable, and the Turing
unstable regimes. In the bistable case stability thresholds are obtained for
the Eckhaus and the zigzag instabilities and for the transition to traveling
waves. Neutral stability curves demonstrate the destabilization of stationary
planar patterns at low wavenumbers to zigzag and traveling modes. Numerical
solutions of the model system support the theoretical findings
Current-induced highly dissipative domains in high Tc thin films
We have investigated the resistive response of high Tc thin films submitted
to a high density of current. For this purpose, current pulses were applied
into bridges made of Nd(1.15)Ba(1.85)Cu3O7 and Bi2Sr2CaCu2O8. By recording the
time dependent voltage, we observe that at a certain critical current j*, a
highly dissipative domain develops somewhere along the bridge. The successive
formation of these domains produces stepped I-V characteristics. We present
evidences that these domains are not regions with a temperature above Tc, as
for hot spots. In fact this phenomenon appears to be analog to the nucleation
of phase-slip centers observed in conventional superconductors near Tc, but
here in contrast they appear in a wide temperature range. Under some
conditions, these domains will propagate and destroy the superconductivity
within the whole sample. We have measured the temperature dependence of j* and
found a similar behavior in the two investigated compounds. This temperature
dependence is just the one expected for the depairing current, but the
amplitude is about 100 times smaller.Comment: 9 pages, 9 figures, Revtex, to appear in Phys. Rev.
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