The odds ratio for the BAL recovery rate failure was analysed using Pearson’s chi-squared test.

(DOCX)</p

Factors affecting the recovery rate of BAL.

Factors affecting the recovery rate of BAL.</p

Additional file 2 of Characteristics of pleural effusion with a high adenosine deaminase level: a case–control study

Additional file 2: Table S1. The area under the receiver operating characteristic curve of predictive factors for the diagnosis of a target disease compared to all other diseases

Flowchart of the study.

BAL bronchoalveolar lavage fluid.</p

A 3D image analysis system using a SYNAPSE VINCENT volume analyser calculated the area of the bronchial wall and bronchial lumen based on the lung analysis (A), lung volume affiliated bronchus in which BAL was performed based on the lung resection analysis (B), and bifurcation numbers of bronchus based on bronchoscopy simulator (C).

A 3D image analysis system using a SYNAPSE VINCENT volume analyser calculated the area of the bronchial wall and bronchial lumen based on the lung analysis (A), lung volume affiliated bronchus in which BAL was performed based on the lung resection analysis (B), and bifurcation numbers of bronchus based on bronchoscopy simulator (C).</p

S1 Fig -

The area of the bronchial wall did not show significant relationships with COPD (having COPD 13.8 mm2 [11.2–15.3] vs. no COPD 14.2 mm2 [10.9–15.3], p = 0.456) in S1A Fig, a target site of BAL (middle/lingual lobe 14.1 mm2 [10.9–18.5] vs. other lobes 14.3 mm2 [11.6–22.7], p = 0.241) in S1B Fig, sex (male 13.8 mm2 [10.4–17.6] vs. female 14.8 mm2 [11.3–19.2], p = 0.169) in S1C Fig, and age (>71 years old median 14.1 mm2 [10.6–19.1] vs. ≤71 years old median 14.2 mm2 [11.2–18.6], p = 0.877) in S1D Fig. (TIF)</p

Additional file 1 of Characteristics of pleural effusion with a high adenosine deaminase level: a case–control study

Additional file 1. Program code for development of a decision tree

Correlation with the recovery rate of bronchoalveolar lavage fluid.

(DOCX)</p

Comparisons between the failure group and the success group.

Comparisons between the failure group and the success group.</p

ROC of the area of the bronchial wall for predicting BAL recovery rate failure.

The AUC was 0.673 (95% CI 0.572 to 0.775). The cut off value, which was decided by a point of maximum sensitivity and specificity, was 10.6 mm2. ROC: receiver operating characteristic curve, AUC: area under the curve, Cl: confidence interval.</p