sweeping the forest floor of frequencies

sweeping the forest floor of frequencies is a Master of Fine Art thesis project comprised of the dossier and the exhibition presented at the Artlab Gallery July 27 - August 11, 2023. My writing and multidisciplinary work foreground sonic, visual, and imperceptible signals as search modes for grounding and interconnectedness. The Comprehensive Artist Statement is the first chapter of the dossier and focuses on drawing, listening, and exploring forms of language as three dominant modes of my practice that reflect my fragmented life between three countries. In its form, the writing embraces fragmentation and iterative growth through refragmentation, drawing on my embodied experience and methods of creation in the studio. The second chapter of the dossier is an interview with Anna Friz at Wave Farm in Acra, NY that includes discussions on radio and transmission art, process-based iterative art practice, engagement of discarded materials and technology in installations, and interdisciplinary research. The third chapter includes selections from the documentation of the exhibition at the Artlab

Effect of AGM and Fetal Liver-Derived Stromal Cell Lines on Globin Expression in Adult Baboon (P. anubis) Bone Marrow-Derived Erythroid Progenitors

This study was performed to investigate the hypothesis that the erythroid micro-environment plays a role in regulation of globin gene expression during adult erythroid differentiation. Adult baboon bone marrow and human cord blood CD34+ progenitors were grown in methylcellulose, liquid media, and in co-culture with stromal cell lines derived from different developmental stages in identical media supporting erythroid differentiation to examine the effect of the micro-environment on globin gene expression. Adult progenitors express high levels of γ-globin in liquid and methylcellulose media but low, physiological levels in stromal cell co-cultures. In contrast, γ-globin expression remained high in cord blood progenitors in stromal cell line co-cultures. Differences in γ-globin gene expression between adult progenitors in stromal cell line co-cultures and liquid media required cell-cell contact and were associated with differences in rate of differentiation and γ-globin promoter DNA methylation. We conclude that γ-globin expression in adult-derived erythroid cells can be influenced by the micro-environment, suggesting new potential targets for HbF induction

Transmitted antiretroviral drug resistance in New York State, 2006-2008: results from a new surveillance system.

HIV transmitted drug resistance (TDR) is a public health concern because it has the potential to compromise antiretroviral therapy (ART) at the population level. In New York State, high prevalence of TDR in a local cohort and a multiclass resistant case cluster led to the development and implementation of a statewide resistance surveillance system.We conducted a cross-sectional analysis of the 13,109 cases of HIV infection that were newly diagnosed and reported in New York State between 2006 and 2008, including 4,155 with HIV genotypes drawn within 3 months of initial diagnosis and electronically reported to the new resistance surveillance system. We assessed compliance with DHHS recommendations for genotypic resistance testing and estimated TDR among new HIV diagnoses.Of 13,109 new HIV diagnoses, 9,785 (75%) had laboratory evidence of utilization of HIV-related medical care, and 4,155 (43%) had a genotype performed within 3 months of initial diagnosis. Of these, 11.2% (95% confidence interval [CI], 10.2%-12.1%) had any evidence of TDR. The proportion with mutations associated with any antiretroviral agent in the NNRTI, NRTI or PI class was 6.3% (5.5%-7.0%), 4.3% (3.6%-4.9%) and 2.9% (2.4%-3.4%), respectively. Multiclass resistance was observed in <1%. TDR did not increase significantly over time (p for trend = 0.204). Men who have sex with men were not more likely to have TDR than persons with heterosexual risk factor (OR 1.0 (0.77-1.30)). TDR to EFV+TDF+FTC and LPV/r+TDF+FTC regimens was 7.1% (6.3%-7.9%) and 1.4% (1.0%-1.8%), respectively.TDR appears to be evenly distributed and stable among new HIV diagnoses in New York State; multiclass TDR is rare. Less than half of new diagnoses initiating care received a genotype per DHHS guidelines

Frequency of ARV drug resistance testing within 3 months of HIV diagnosis, New York State 2006–2008^†.

†<p>Excludes persons aged 12 years or younger and persons perinatally infected.</p>*<p>Multivariate logistic regression excludes cases with missing data except for missing VL and missing risk which is categorized as “No identifiable risk”.</p>**<p>Represents total after removal of 3324 cases missing CD4, VL and/or genotype within three months of diagnosis.</p

Top 10 mutations by drug class.

<p>Top 10 mutations by drug class.</p

Frequency of TDR genotypes by demographic characteristics, New York State 2006–2008.

*<p>Multivariate logistic regression excludes cases with missing data except for missing risk which is categorized at “No identifiable risk”.</p

Reference values for local arterial stiffness. Part A: carotid artery

Non-invasive measures of common carotid artery properties, such as diameter and distension, and pulse pressure, have been widely used to determine carotid artery distensibility coefficient - a measure of carotid stiffness (stiffness ∼1/distensibility coefficient). Carotid stiffness has been associated with incident cardiovascular disease (CVD) and may therefore be a useful intermediate marker for CVD. We aimed to establish age and sex-specific reference intervals of carotid stiffness