Tapered Double Cantilever Beam Fracture Tests of Phenolic-Wood Adhesive Joints: Part II. Effects of Surface Roughness, the Nature of Surface Roughness, and Surface Aging on Joint Fracture Energy

Tapered double cantilever beam specimens were used to test the effect of surface roughness, the nature of surface roughness, and surface aging on the fracture energy of phenolic-wood adhesive joints. The fracture energy and the failure characteristics of the joints were found to depend not only on the surface roughness but also on the method of surface preparation. The fracture energy increased monotonically with surface roughness for specimens derived from hand-sanded surfaces but exhibited a minimum for specimens obtained from machine-sanded surfaces. Generally, joints from hand-sanded surfaces had higher fracture energies than those derived from the machine-sanded surfaces. Within the joints derived from the machine-sanded surfaces, those sanded perpendicular to the direction of crack growth had higher fracture energies than those sanded parallel to the direction of crack growth. Aging surfaces prior to bonding significantly decreased adhesive joint strength.Notwithstanding the differences in roughness, microscopic examination revealed little difference in the appearance of the sanded surfaces. Adhesive did not penetrate hand-sanded surfaces to any appreciable extent, but did deeply penetrate both the vessel and fiber lumens on the machine-sanded surfaces. Microscopic examination of the fractured surfaces did reveal significant differences that related to the fracture toughness of the bond

Characterization of IgA response among women with incident HPV 16 infection

AbstractPrevious studies have characterized the prevalence and duration of serum IgG antibodies to human papillomavirus type 16 (HPV 16) in a well-studied cohort of college women, using viruslike particle- (VLP) based ELISAs. In this study IgA antibodies in cervical secretions and sera were examined using a newly developed capsomer-based ELISA and the patterns observed for serum IgG, serum IgA, and cervical IgA antibodies were compared. The median time to antibody detection from the first detection of HPV 16 DNA was 10.5 months for IgA in cervical secretions and 19.1 months for serum IgA. Serum IgA antibody conversion was observed less frequently and occurred later than IgA conversion in cervical secretions (P = 0.011) or serum IgG conversion (P = 0.051). The median time to antibody reversion, following seroconversion, was 12.0 months for IgA in cervical secretions and 13.6 months for serum IgA, whereas approximately 20% of women with serum IgG antibodies reverted within 36 months. Thus, the duration of IgA in cervical secretions and sera was shorter than the duration of serum IgG (P = 0.007 and 0.001)