20 research outputs found
A Novel Method for the High-Pressure-Promoted, Uncatalyzed Aza-Michael Reaction of Nitrogen Heterocycles with Enones in Water
Full text linkA Direct Method for ÎČ-Selective Glycosylation with an N-Acetylglucosamine Donor Armed by a 4-O-TBDMS Protecting Group
No full textA new direct method for ÎČ-selective glycosylation with an N-acetylglucosamine (GlcNAc) donor was developed. This substrate, which can be readily prepared from commercially available GlcNAc in two steps, contains a 4-O-tert-butyldimethylsilyl (TBDMS) protecting group as a key component. We found that this functionality could have a favorable effect on the reactivity of the GlcNAc donor. Glycosylation with the armed donor using primary alcohols in the presence of a catalytic amount of trimethylsilyl trifluoromethanesulfonate (TMSOTf) in 1,2-dichloroethane smoothly gave the desired coupling products in good yields with complete ÎČ-selectivity, while sterically hindered acceptors were less efficient
High pressure promoted aza-Michael addition of primary and secondary amines to α-substituted acrylates
No full textInternational audienc
Formylation of amines through catalyst- and solvent-free transamidation reaction
No full textInternational audienc
Trifluoromethanesulfonic Acid, an Unusually Powerful Catalyst for the Michael Addition Reaction of ÎČ-Ketoesters under Solvent-Free Conditions
No full textSynthesis of Novel Chiral Diazole Derivative Ligands for the Enantioselective Addition of Diethylzinc to Benzaldehyde
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Organocatalytic Asymmetric Hetero-Diels-Alder Reaction of Oxindoles under High Pressure
No full textInternational audienc
Effects of scavengers for active oxygen species on photoresponse and photodynamic damages to a pigmented protozoan, Blepharisma
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