11 research outputs found

    Detection of HPV16/18 neutralizing antibodies.

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    <p>Presence of antibodies to HPV types 16 and 18 by a VLP-based competitive Luminex immunoassay (cLIA). Results are presented as percentage of total number of available blood samples (N = 160).</p

    Prevalence of HPV 16 and 18 in women with cervical cancer.

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    <p><b>A</b>. Percentage of positive samples for HPV 16 and 18 by PCR (n = 166). Untyped samples were negative for both HPV 16 and 18. <b>B</b>. Percentage of positive samples for HPV 16 only, HPV 18 only (mono-infection) or both HPV 16 and 18 (co-infection) by PCR (n = 135). <b>C</b>. Repartition into age groups of positive samples for HPV 16 or HPV 18 (mono-infection) or for both (co-infection) by PCR. For mono- and co-infections, lighter shades represent the percentage of infected women within the co- or mono-infected group aged 49 years or younger; darker shades represent the percentage of infected women aged 50 years or older.</p

    Willingness to participate and who would give permission for participation in a HPV vaccine trial.

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    <p>The percentage of women willing to participate in a HPV vaccine trial is represented by age group with the line. The bars represent the number of women answering the question who would give permission to participate to a HPV vaccine trial per age group. The answers were myself only (dark blue), husband and myself (purple), husband only (pink), father, husband and myself (light blue), parents, husband and myself (light green), mother only (dark green), or no answer (grey). In the oldest age group, the * asterix indicates data that only includes 3 patients.</p

    Willingness to participate in vaccination.

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    <p><i>Note. HPV = human papillomavirus, USD = United States dollars</i>.</p>9<p>All participants were asked this question. This question was hypothetical for those without children.</p>10<p>Percentages do not equal 100% due to rounding.</p>11<p>Converted from CFA using an exchange rate of 539.4CFA/USD.</p

    Data_Sheet_1_A story-telling cloth approach to motivating cervical cancer screening in Mali.docx

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    Ninety percent of deaths from Cervical cancer (CC) caused by Human Papilloma Virus (HPV) occur in low- and middle-income countries. CC is the 2nd most common cause of cancer in women in West Africa, where 12,000 women develop cervical cancer and more than 6,000 die from the disease, annually. While HPV vaccination and CC screening have dramatically reduced the incidence of CC and mortality from CC in developed countries, prevention of CC in West Africa is often limited to visual inspection of the cervix and surgical intervention. In previous studies of CC in Mali, we demonstrated that knowledge about the link between HPV and CC is limited, and that screening for CC is often delayed until women are symptomatic. For this intervention, a story-telling cloth (West African-style printed pagne) was designed for use as a starting point for educational sessions run by community health workers. Community outreach using the cloth during 6 months of 2015 resulted in a 5-fold higher uptake of cervical cancer screening and increased awareness of the potential to vaccinate adolescents against CC. 3,271 women were motivated to visit one of five participating clinics for CC screening, where a mere 600 women had been screened during the previous year. This study shows that a comprehensive, visual, community-centered education campaign coupled with coordinated support for local clinics improves uptake of CC screening.</p
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