Additional file 1: Table S1. of Longitudinal alterations in health-related quality of life and its impact on the clinical course of patients with advanced hepatocellular carcinoma receiving sorafenib treatment

Changes in HRQOL domain scores in the 12 months prior to death. Table S2. Changes in HRQOL domain scores in patients who survived >1 year (n = 13). Figure S1. Graphical display of the distribution of sorafenib-related adverse events (n = 54). Figure S2. Graphical representation of HRQOL domain score changes of patients receiving sorafenib over the course of one year (n = 13). Figure S3. Graphical representation of HRQOL domain score changes with/without grade 3 adverse events. Figure S4. Cumulative discontinuation incidence curves stratified by factors associated with treatment duration: social functioning (SF) scores. (DOCX 553 kb