Does celiac disease impair coronary microvascular circulation: Coronary flow velocity reserve of patients with celiac disease

Background Celiac disease (CD) is an enteropathy characterized with immune reaction to gliadin protein. Aim In this study, we aimed to assess effect of CD on coronary microvascular circulation and the association between coronary flow velocity reserve (CFVR) and hs-CRP/Albumin ratio. Material and Methods Study was conducted between March 2017 and November 2018 with CD at Umraniye Training and Research Hospital Gastroenterology Clinic. CFVR was defined as the ratio of hyperemic to baseline diastolic peak velocities. CFVR >= 2.0 was considered normal. C-reactive protein/albumin ratio (CAR) was calculated as hs-CRP/albumin. Results Serum albumin (4.27 +/- 0.56 vs 4.50 +/- 0.34; P value: .04) level was significantly lower in celiac group but higher Hs-CRP (2.44 +/- 1.24 vs 1.82 +/- 1.29; P value < .01), hs-CRP/albumin ratio (0.57 +/- 0.30 vs 0.41 +/- 0.31; P value: .03) were recorded in celiac group. Both hyperemic flow and CFVR substantially lower in the celiac group compared to controls. In univariate analysis; age, hs-CRP, and hs-CRP/albumin ratio were associated with low CFVR and hs-CRP/albumin level was an accurate predictor of low CFVR at the ROC curve. Conclusion In this study, we found that in patients with CD, coronary flow reserve is impaired

Does celiac disease impair coronary microvascular circulation: Coronary flow velocity reserve of patients with celiac disease

Background Celiac disease (CD) is an enteropathy characterized with immune reaction to gliadin protein. Aim In this study, we aimed to assess effect of CD on coronary microvascular circulation and the association between coronary flow velocity reserve (CFVR) and hs-CRP/Albumin ratio. Material and Methods Study was conducted between March 2017 and November 2018 with CD at Umraniye Training and Research Hospital Gastroenterology Clinic. CFVR was defined as the ratio of hyperemic to baseline diastolic peak velocities. CFVR >= 2.0 was considered normal. C-reactive protein/albumin ratio (CAR) was calculated as hs-CRP/albumin. Results Serum albumin (4.27 +/- 0.56 vs 4.50 +/- 0.34; P value: .04) level was significantly lower in celiac group but higher Hs-CRP (2.44 +/- 1.24 vs 1.82 +/- 1.29; P value < .01), hs-CRP/albumin ratio (0.57 +/- 0.30 vs 0.41 +/- 0.31; P value: .03) were recorded in celiac group. Both hyperemic flow and CFVR substantially lower in the celiac group compared to controls. In univariate analysis; age, hs-CRP, and hs-CRP/albumin ratio were associated with low CFVR and hs-CRP/albumin level was an accurate predictor of low CFVR at the ROC curve. Conclusion In this study, we found that in patients with CD, coronary flow reserve is impaired

HOW DO WE FOLLOW THE GUIDELINES IN THE TREATMENT OF PATIENTS WITH TYPE 2 DIABETES?

Objective: We aimed to retrospectively investigate compliance with guidelines in order to increase the awareness of physicians towards current treatment approaches and goals in Type 2 diabetes mellitus (DM)

Lipid profile, atherogenic indices, and their relationship with epicardial fat thickness and carotid intima-media thickness in celiac disease

OBJECTIVE: In this study, we aimed to investigate the presence of subclinical atherosclerosis by measuring epicardial fat thickness (EFT) and carotid intima-media thickness (cIMT), evaluate low-level inflammation with high-sensitivity C-reactive protein (hsCRP), and evaluate whether there is a relationship among lipid profile, atherogenic indices, and hsCRP with these subclinical atherosclerosis markers in patients with celiac disease (CD)