Occupational allergic respiratory diseases - occupational asthma

Introduction and objective: Occupational diseases, most often caused by allergens or irritants in the workplace, lead to a deterioration in the quality of life of employees and, in some cases, the inability to continue working in a specific position.It is important to prevent respiratory diseases, which will allow for earlier detection of changes and appropriate treatment. The aim of the study is to present the knowledge about occupational asthma on the basis of available scientific data, and to indicate appropriate preventive measures to reduce the incidence of this disease entity. Review methods:While writing the thesis, a database was used, ie Pubmed and Google Scholar. Brief description of the stage of knowledge: The group of the most common obstructive pulmonary diseases is bronchial asthma. This disease affects over a dozen percent of the population of civilized countries, and it affects various age groups and various social strata. Bronchial asthma can be mild, severe, and even fatal [1]. Occupational asthma is caused by inhaling antigens, which are abundant in the working environment of farmers, bakers and millers, including protozoa and airborne fungi. Summary: Allergic respiratory diseases are a significant problem in the work environment. In addition, an increase in these diseases has been observed in recent years. It is related to the improvement of diagnostic methods, as well as their more frequent occurrence [2]. The frequency and type of allergy occurrence depends on many factors. These factors include genetics, exposure to aeroallergens, and the type of work performed. Certain professions are associated with a particularly high risk of allergic respiratory disease. Such occupations include a baker, miller, and employees in the transport industry [3]

Extrinsic allergic pneumonitis - classification, pathogenesis, diagnosis

Introduction and objective: Extrinsic allergic pneumonitis (AZPP) is an inflammatory disease of the lung parenchyma and bronchioles, caused by inhalation of organic and inorganic antigens. The pathhomechanism of the disease is based on the binding of the antigen with precipitins to form immune complexes that are responsible for the formation of acute inflammation in the lung tissue. The resulting inflammation is a type III and type IV hypersensitivity reaction. In the clinical course, azpp is divided into acute, subacute and chronic phases. The course of the disease varies depending on the type and duration of exposure to the antigen. It is most often manifested by shortness of breath, coughing and the progression of the disease leads to respiratory failure. Review methods: While writing the thesis, a database was used, ie Pubmed and Google Scholar. Brief description of the stage of knowledge: Extrinsic allergic pneumonitis requires a thorough differential diagnosis, which includes laboratory tests, functional tests, imaging tests, inhalation provocation tests and lung biopsy. The mainstay of treatment is to avoid exposure to the antigen. In severe disease, systemic corticosteroid therapy is indicated. Summary: Correct diagnosis is a big problem because of the differences in symptoms and the severity of the disease among patients. Expanding the knowledge about the clinical course of the disease or its pathogenesis will affect the effectiveness of diagnostics and help to develop new methods of treatment. &nbsp