Hepatitis B Virus Knowledge and Vaccination Status among Health‐care Workers in Calabar, Nigeria

Background and Objectives: The World Health Organization estimates that 2 million health‐care workers (HCWs) are at risk of occupational exposure to hepatitis B virus (HBV), with the majority (90%) of such infections arising in sub-Saharan Africa. This study aimed to determine HBV knowledge and vaccination uptake among HCWs. Materials and Method: This was a cross sectional analytical study conducted among 392 HCWs from two major health institutions in Calabar i.e. the University of Calabar Teaching Hospital (UCTH) and the General Hospital Calabar (GHC), Cross river State. Multi-staged sampling method comprising of two stages was used to recruit participants into the study. The study population comprised of doctors, nurses, laboratory scientists/technologist, and other categories of HCWs such as pharmacists, ward orderlies, and mortuary attendants. A semi-structured self-administered questionnaire was used to obtain data on the socio-demographic characteristics of HCWs, the knowledge of HCWs regarding HBV and vaccine. The analysis of data was done using the Statistical Package for Social Sciences version 20. Study Design: This was a cross-sectional, study of HCWs in Calabar. Sampling Method: Multi-staged sampling method was used to select participants from two major health institutions in Calabar, i.e., the University of Calabar Teaching Hospital (UCTH) and the General Hospital Calabar (GHC). Thereafter, through balloting, simple random sampling technique was used to recruit the participants. Study Population: Three hundred and ninety-two HCWs were recruited from UCTH and GHC under the following categories: doctors, nurses, laboratory scientists/technologist, and other categories of HCWs such as pharmacists, ward orderlies, and mortuary attendants. Data Management: A semi-structured self-administered questionnaire was used to obtain data on the socio-demographic characteristics of HCWs, the knowledge of HCWs regarding HBV and vaccine. The analysis of data was done using the Statistical Package for Social Sciences version 20. Results: Overall, 67.9% of the respondents were found to have adequate knowledge of HBV vaccination and infection. Less than half (43.4%) of HCWs admitted receiving three doses (i.e., full coverage) of the vaccine. Difficulty in accessing the vaccine (48, 23.4%) was identified as the major reason given for suboptimal vaccination. Conclusion: The knowledge of HBV infection and vaccination is quite modest among HCWs in Calabar. Despite this observation, the vaccination status among HCWs is unsatisfactory. The implication of the findings of our study for health policy and practice is to prevent further occupational exposure of HCWs to HBV infection through mandatory vaccination

Prevalence of Helicobacter pylori infection among dyspepsia patients in Calabar

Helicobacter pylori is an ubiquitous organism. It is estimated that more than 50% of the world’s population is infected with the bacteria. The infection is typically acquired in infancy and has been associated with poor living conditions and low socio-economic status. Once helicobacter pylori is acquired, it commonly persists lifelong unless treated. This pathogen has been implicated as a major aetiologic agent in the pathogenesis of peptic ulcer disease and is an established carcinogen. The aim of this study was to determine the prevalence of helicobacter pylori infection among our dyspeptic patients. This was a retrospective study conducted from April 2014 to December 2018. A total of one hundred and fifteen (115) patients who had symptoms of dyspepsia were recruited within this period of time. The presence of helicobacter pylori was determined using urea breath test. The results showed that 42.6% of the patients were positive for helicobacter pylori, while 51.3% of patients had a negative result. A borderline result was seen in 6.1% of patients. The mean age of the studied population was 45.10 years (SD= 12.55), with most patients aged between 41-60 years. This study showed no sex predilection, with an equal sex distribution of the study participants. Reports from other parts of the country also found the prevalence of helicobacter pylori to be highest in individuals between the 4th and 5th decade of life. This study concluded that the prevalence of helicobacter pylori infection is relatively high among patients with dyspepsia in South South Nigeria.Keywords: Helicobacter pylori, dyspepsia, urea breath test, South South Nigeri