Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) in association with an adenocarcinoma: a case report

<p>Abstract</p> <p>Introduction</p> <p>Diffuse idiopathic pulmonary neuroendocrine cell hyperplasia (DIPNECH) is a rare disorder and information on this disease is limited, especially with regard to its management and prognosis. It has become generally accepted that DIPNECH is a precursor lesion to pulmonary carcinoid tumors.</p> <p>Case presentation</p> <p>Here we report on a 60-year-old female patient with DIPNECH and an associated pulmonary adenocarcinoma.</p> <p>Conclusion</p> <p>This case contributes to a better understanding of the disorder and its associated pathologies.</p

Final risk prediction model of in-hospital mortality after pneumonectomy in the discovery set based on data from 542 consecutive pneumonectomies that were performed between 2003 to 2007.

<p>CI = confidence interval.</p><p>¶ High leukocyte counts were not considered “yes” if related to steroids or immunosuppression with no clinical signs of infection.</p><p>Final risk prediction model of in-hospital mortality after pneumonectomy in the discovery set based on data from 542 consecutive pneumonectomies that were performed between 2003 to 2007.</p

Characteristics of 232 consecutive pneumonectomies from 2008 to 2010 (validation set).

<p>ASA = American Association of Anesthesiologists.</p><p>Characteristics of 232 consecutive pneumonectomies from 2008 to 2010 (validation set).</p

Characteristics of 542 consecutive pneumonectomies from 2003 to 2007 (discovery set).

<p>ASA = American Association of Anesthesiologists. FEV1 = median forced expiratory volume in 1 second. FVC = median forced vital capacity.</p><p>*Pneumonectomies with resections of the atrium, diaphragm, chest wall or superior vena cava were defined as other extensions.</p><p>Characteristics of 542 consecutive pneumonectomies from 2003 to 2007 (discovery set).</p

Definitions of the comorbidities according to the International Classification of Diseases (ICD) version 10.

<p>Definitions of the comorbidities according to the International Classification of Diseases (ICD) version 10.</p

Selected studies of preoperative risk factors for mortality after pneumonectomy.

<p>FEV1/ FVC = forced expiratory volume in 1 second/ forced vital capacity; DLCO = diffusion capacity of lung to carbon monoxide.</p><p>Selected studies of preoperative risk factors for mortality after pneumonectomy.</p