2,413 research outputs found

    The Adsorption of CHS-1 Resin for Cr (VI) of Low Concentration from Electroplating Wastewater

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    AbstractThe adsorption property of CHS-1 resin for Cr (VI) was investigated by chemical analysis. Experiment results show that CHS-1 resin has the best adsorption ability for Cr (VI) at pH=2-3. The exchange adsorption rate of the resin for Cr (VI) at low concentration is controlled by liquid film diffusion and chemical reaction. The behavior obeys the Freundlich isotherm and Langmuir equation. Its saturated sorption capacity is 347.22mg/g at 298K. The thermodynamic adsorption parameters, enthalpy change ΔH and free energy change ΔG298 of the adsorption are 1.39kJ/mol and -5.3kJ/mol. Cr (VI) adsorbed on CHS-1 resin can be eluted by 5% NaOH -5% NaCl quantitatively without apparent decrease in sorption capacity

    Far-Field Tunable Nano-focusing Based on Metallic Slits Surrounded with Nonlinear-Variant Widths and Linear-Variant Depths of Circular Dielectric Grating

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    In this work, we design a new tunable nanofocusing lens by the linear-variant depths and nonlinear-variant widths of circular grating for far field practical applications. The constructively interference of cylindrical surface plasmon launched by the subwavelength metallic structure can form a subdiffraction-limited focus, and the focal length of the this structures can be adjusted if the each groove depth and width of circular grating are arranged in traced profile. According to the numerical calculation, the range of focusing points shift is much more than other plasmonic lens, and the relative phase of emitting light scattered by surface plasmon coupling circular grating can be modulated by the nonlinear-variant width and linear-variant depth. The simulation result indicates that the different relative phase of emitting light lead to variant focal length. We firstly show a unique phenomenon for the linear-variant depths and nonlinear-variant widths of circular grating that the positive change and negative change of the depths and widths of grooves can result in different of variation trend between relative phases and focal lengths. These results paved the road for utilizing the plasmonic lens in high-density optical storage, nanolithography, superresolution optical microscopic imaging, optical trapping, and sensing.Comment: 14pages,9figure

    Feasibility and effectiveness of heat pipe cooling in end milling operations : thermal, structural static, and dynamic analyses : a new approach

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    In this paper, the feasibility and effectiveness of heat pipe cooling in end milling operations are investigated. A new embedded heat pipe technology was utilized to remove the heat generated at the tool-interface in end milling processes. Numerical studies involved four cases, including dry milling, fluid cooling, heat pipe cooling, and heat pipe cooling with cutting fluid supplied. The thermal, structural static, and dynamic characteristics of the endmill were investigated using a numerical calculation with fast finite element plus solvers based on explicit finite element analysis software. The results demonstrate that the heat pipe end-mill is most feasible and effective in the actual end milling processe

    Structural design of a silicon six-wafer micro-combustor under the effect of heat transfer boundary condition at the outer walls

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    The aim of this investigation was to establish a methodology for designing highly stressed micro fabricated structures by studying the structural design issues associated with a silicon six–wafer micro combustor under the effect of heat transfer boundary condition at the outer walls. Some experimental and numerical simulation results have indicated that the flame can not be sustained in the micro combustor if the poor heat transfer coefficients at the outer wall are present. This could cause the combustor wall temperature higher than the auto ignition temperature of reactants and results in the upstream burning. Since silicon has relatively poor high temperature strength and creep resistance when the temperature is above the brittle to ductile transition temperature (BDTT), e.g. 900K, the combustion in the recirculation jacket could possibly damage the micro combustor due to the high wall temperature

    Experimental analyses to investigate the feasibility and effectiveness in using heat pipe-embedded drills

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    This paper presents an experimental investigation to verify the feasibility and effectiveness of heat pipe cooling in drilling operations. The basic idea is to insert a heat pipe at the center of the drill tool with the evaporator close to the drill tip and the condenser at the end of the drill. Consequently, the heat generated at the tool–chip interface can be removed by convection heat transfer. Experimental studies were involved in three cases, including solid drill without coolant, solid drill with coolant, and heat pipe drill. Drilling tests were conducted on a CNC machining center with full immersion cutting. The cast iron square block was used as the workpiece, and the high-speed steel was chosen for the drill tool material. Flank wear is considered as the criterion for tool failure, and the wear was measured using a Hisomet II Toolmaker’s microscope. The tests were conducted until the drill was rejected when an average flank wear greater than 0.10 mm was recorded. The results demonstrate that using a heat pipe in the drilling process can effectively perform thermal management comparable to the flooding coolant cooling used pervasively in the manufacturing industry, extending the tool life of the drill

    Effects of high glucose on expression of OPG and RANKL in rat aortic vascular smooth muscle cells

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    AbstractObjectiveTo explore effect of high glucose on expression of osteoprotegerin (OPG) and receptor activator of NF– κ B ligand (RANKE) in rat aortic vascular smooth muscle cells.MethodsSD rats were intraperitoneally injected with streptozotocin, OPG and RANKL expression in rat thoracic aortas were detected by immunohistochemical staining. In cultured vascular smooth muscle cells (VSMCs) (A7r5), qRT–PCR and Western blot analysis were used to examine the mRNA and protein levels of OPG and RANKL.ResultsOur results demonstrated that OPG expression was increased in hyperglycemic rat aortic VSMCs, while RANKL expression was decreased. Besides, in vitro experiments high glucose induced OPG expression, but depressed RANKL expression by dose– and time–dependent manner in cultured A7r5.ConclusionsOur findings suggested that high glucose could promote the expression of OPG, and inhibit the expression of RANKL in VSMCs, which may be partly be the molecular mechanism of diabetic vascular calcification

    Case report: Primary pericardial angiosarcoma, a rare cause of cardiac tamponade

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    Primary pericardial angiosarcoma is a rare malignancy of the pericardium with variable clinical features and imaging characteristics. Herein, we report a case of histopathologically confirmed pericardial angiosarcoma in a 66-year-old man. The patient developed cardiac tamponade in a short time period. The transthoracic echocardiography showed the presence of multiple irregular echodensities, heterogeneous in echogenicity, encasing the apex of both ventricles in the pericardial space, initially misinterpreted as pericardial effusion. The patient died of cardiogenic shock despite undergoing a surgical pericardiectomy. Pericardial angiosarcoma can manifest as a mass obliterating the pericardial sac, rather than the typical pericardial effusion observed on echocardiography. Multimodality imaging studies aid in diagnosing primary pericardial angiosarcoma, but the final diagnosis relies on tissue histopathology

    Enhanced antitumor immunity by targeting dendritic cells with tumor cell lysate-loaded chitosan nanoparticles vaccine

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    Whole tumor cell lysates (TCL) have been implemented as tumor antigens for cancer vaccine development, although clinical outcomes of TCL-based antitumor immunotherapy remain unsatisfactory. In order to improve the efficacy of TCL-based vaccines, biomaterials have been employed to enhance antigen delivery and presentation. Here, we have developed chitosan nanoparticles (CTS NPs) with surface mannose (Man) moieties for specific dendritic cells (DCs) targeting (Man-CTS NPs). The Man-CTS NPs were then loaded with TCL generated from B16 melanoma cells (Man-CTS-TCL NPs) for in vitro and in vivo assessment. Potency of the Man-CTS-TCL NPs as cancer vaccine was also assessed in vivo by immunization of mice with Man-CTS-TCL NPs followed by re-challenge with B16 melanoma cell inoculation. We have shown here that Man-CTS-TCL NPs promote bone marrow-derived dendritic cells (BMDCs) maturation and antigen presentation in vitro. In vivo evaluation further demonstrated that the Man-CTS-TCL NPs were readily taken up by endogenous DCs within the draining lymph node (DLN) following subcutaneous administration accompanied by increasing in serum IFN-γ and IL-4 levels. Tumor growth was also significantly delayed in mice primed with Man-CTS-TCL NPs vaccine, attributable at least in part to cytotoxic T lymphocytes response. Moreover, Man-CTS-TCL NPs vaccine also exhibited therapeutic effects in mice with melanoma. Thus, we report here the Man-CTS-TCL NPs as effective anti-tumor vaccine for cancer immunotherapy

    Numerical simulation on the aerodynamic performance of the high-speed train under crosswinds

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    With the continuously increased speed of the high-speed train, the lateral aerodynamic performance of high-speed trains has attracted more and more attention. Under strong crosswinds, the aerodynamic performance of trains deteriorate and air drag, lift and lateral forces borne by trains quickly increase, which has an impact on the lateral stability of trains and even leads to train derailment. This paper adopted computational fluid dynamics theory to establish an aerodynamic model for a high-speed train, computed aerodynamic forces and moments acting on the high-speed train and obtained the unsteady flow field of the high-speed train. In the meanwhile, this paper combined with multi-body system dynamics theory to establish a system dynamics model for the train and analyzed the safe aerodynamic performance of the high-speed train under cross winds. Computational results showed: Under cross winds, the aerodynamic performance of the high-speed train had a random fluctuation. When wind direction angle was 90°, aerodynamic forces (drag, lift and lateral forces) and moments (overturning moment, shaking moment and nodding moment) borne by the high-speed train were the largest; train speed was a main factor affecting the size of positive pressures of train and cross wind velocity had no obvious impacts on the positive and negative pressures of train body; the aerodynamic forces and moments of the high-speed train had a random fluctuation within a certain range with time; the frequency for the peak value of power spectral density of lateral forces of head train was within 25 Hz and the peak value of power spectral density was the largest when the main frequency was 1.6 Hz; the frequency for the peak value of power spectral density of overturning moment of head train was within 20 Hz and main frequency was 0.57 Hz. When the cross wind speed was 15 m/s, all safety indexes of the high-speed train running at the speed of 250 km/h were within the range of limited values and satisfied design requirements. Aerodynamic performance of the high-speed train with the suction chamber under the cross wind was computed and compared with original results. Aerodynamic force and force moments of the high-speed train under cross wind will be reduced obviously and running safety of the high-speed train can be improved through application of the suction chamber

    Bacterial Community Diversity and Screening of Growth-Affecting Bacteria From Isochrysis galbana Following Antibiotic Treatment

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    Algal cultures are generally co-cultures of algae and bacteria, especially when considering outdoor cultivation. However, the effects of associated bacteria on algal growth remain largely unexplored, particularly in the context of Isochrysis galbana. In the present study, we investigated the effects of antibiotic on the growth of I. galbana and its associated bacterial community. We found advantageous responses of I. galbana to antibiotic exposure, evidenced by the increased growth, and the maximal photochemical efficiency of PSII (Fv/Fm). Since antibiotics can cause major disturbances within bacterial community, we further conducted 16S rDNA amplicon sequencing to determine the changes of bacterial community diversity following antibiotic treatment. We found that antibiotic treatment considerably and negatively affected the abundance and diversity of bacterial community, and 17 significantly decreased bacterial species in the antibiotic-treated medium, including Pseudomonas stutzeri, were identified. Further co-culture experiments revealed that P. stutzeri inhibited the growth of I. galbana, and the inhibitory activity was retained in the cell-free bacterial filtrate. These results indicated that the negative effect of bacteria was not exclusively transmitted through contact with I. galbana but could be also mediated via secretory compounds. Taken together, our findings not only fully characterized the bacterial community associated with I. galbana and how the bacterial community changed in response to antibiotic perturbations, but also provided a valuable information about the interactions between I. galbana and its associated bacteria, which might help improve the yield, and quality of I. galbana during its cultivation processes
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